The omega‐6 fatty acid derivative 15‐deoxy‐Δ 12,14 ‐prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress

• Published in: The Journal of physiology Vol. 590; no. 11; pp. 2739 - 2750
• Main Authors: Abdo, Hind, Mahé, Maxime M., Derkinderen, Pascal, Bach‐Ngohou, Kalyane, Neunlist, Michel, Lardeux, Bernard
• Format: Journal Article
• Language: English
• Published: 01.06.2012

Key points Enteric glial cells play a major role in the regulation of enteric neuronal functions. 15‐Deoxy‐Δ 12,14 ‐prostaglandin J2 (15d‐PGJ2) is an omega‐6 fatty acid derivative that was recently identified as a novel glial‐derived mediator involved in the control of the proliferation and differen...