Abstract 924: In vitro study of the potential antineoplastic effect of synthetic naphthoquinones in cisplatin-resistant ovarian cancer lineage

• Published in: Cancer research (Chicago, Ill.) Vol. 72; no. 8_Supplement; p. 924
• Main Authors: Daltoé, Renata D., Madeira, Klesia P., Herlinger, Alice L., Allochio-Filho, João F., Rezende, Lucas CD, Cerri, Murilo F., Guimarães, Isabella S., Valadão, Iuri C., Teixeira, Sarah F., Greco, Sandro J., Rangel, Leticia BA
• Format: Journal Article
• Language: English
• Published: 15.04.2012

Abstract Background: Cancer development has been associated with alterations in polyamine biosynthesis and metabolism, which induce cell proliferation, angiogenesis, expression of genes related to tumor invasion and metastasis; whereas inhibit apoptosis. Based on the strong rational to develop novel...