Abstract 1222A: Identification and targeting of CD34+CD176+IL1RAP+ chronic myeloid leukemia stem cells with bi-specific antibodies

Abstract Leukemia Stem Cells (LSCs) quiescence in Chronic Myeloid Leukemia (CML) plays a major role in therapeutic resistance and disease progression calling for the need for identifying and targeting such cells (1). LSCs belong to the primitive population; CD34+CD38-Lin-, which can’t distinguish no...

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Published inCancer research (Chicago, Ill.) Vol. 79; no. 13_Supplement; pp. 1222 - 1222A
Main Authors Elsawi, Raghda E., Wu, ChengXiang, Younes, Soha, Mohammed, Eman Abdel-Momen, Robinson, James E., Badr, Fouad Mohammed, Braun, Stephen E.
Format Journal Article
LanguageEnglish
Published 01.07.2019
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