Metastatic Medullary Thyroid Carcinoma without Evident Thyroid Nodules: A Rare Presentation

Introduction: Uncommon thyroid and neuroendocrine tumor; medullary thyroid carcinoma (MTC) is a rare, aggressive malignancy, with a 10-year survival rate of roughly 50%. Clinical presentation of MTC differs from sporadic to familial variety, but frequently it is showcased as a painless thyroid nodul...

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Published inScholars Journal of Medical Case Reports Vol. 11; no. 9; pp. 1685 - 1689
Main Authors Rizkou, Fatima Ezzahra, Moufannane, Malak, Benhoummad, Othmane, Rochdi, Youssef, Raji, Abdelaziz
Format Journal Article
LanguageEnglish
Published 15.09.2023
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Abstract Introduction: Uncommon thyroid and neuroendocrine tumor; medullary thyroid carcinoma (MTC) is a rare, aggressive malignancy, with a 10-year survival rate of roughly 50%. Clinical presentation of MTC differs from sporadic to familial variety, but frequently it is showcased as a painless thyroid nodule. Metastatic medullar carcinoma without nodules is scanty, adding to the unpredictable behaviors of this entity. Case Presentation: Thus; the report of this rare presentation in 57-year-old patient with cervical metastatic lymphadenopathy, and a normal sized thyroid and no distant metastases, to which the patient underwent a chemo/ radiotherapy because the encompassment of the vascular axis. Conclusion: Metastasis medullary thyroid carcinoma with normal-size thyroid is somehow unheard of in the literature, as this rare aggressive tumor is usually diagnostic at a stage where the thyroid nodule is accompanied with lymph node metastases.
AbstractList Introduction: Uncommon thyroid and neuroendocrine tumor; medullary thyroid carcinoma (MTC) is a rare, aggressive malignancy, with a 10-year survival rate of roughly 50%. Clinical presentation of MTC differs from sporadic to familial variety, but frequently it is showcased as a painless thyroid nodule. Metastatic medullar carcinoma without nodules is scanty, adding to the unpredictable behaviors of this entity. Case Presentation: Thus; the report of this rare presentation in 57-year-old patient with cervical metastatic lymphadenopathy, and a normal sized thyroid and no distant metastases, to which the patient underwent a chemo/ radiotherapy because the encompassment of the vascular axis. Conclusion: Metastasis medullary thyroid carcinoma with normal-size thyroid is somehow unheard of in the literature, as this rare aggressive tumor is usually diagnostic at a stage where the thyroid nodule is accompanied with lymph node metastases.
Author Moufannane, Malak
Raji, Abdelaziz
Benhoummad, Othmane
Rochdi, Youssef
Rizkou, Fatima Ezzahra
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  surname: Rochdi
  fullname: Rochdi, Youssef
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  givenname: Abdelaziz
  surname: Raji
  fullname: Raji, Abdelaziz
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