Rare chromosomal deletions and duplications increase risk of schizophrenia
Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90% (ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have...
Saved in:
| Published in | Nature Vol. 455; no. 7210; pp. 237 - 241 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
11.09.2008
Nature Publishing Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90% (ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have been identified in individual patients with schizophrenia and also in neurodevelopmental disorders, but large-scale genome-wide surveys have not been performed. Here we report a genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high-density microarrays. For CNVs that were observed in less than 1% of the sample and were more than 100 kilobases in length, the total burden is increased 1.15-fold in patients with schizophrenia in comparison with controls. This effect was more pronounced for rarer, single-occurrence CNVs and for those that involved genes as opposed to those that did not. As expected, deletions were found within the region critical for velo-cardio-facial syndrome, which includes psychotic symptoms in 30% of patients. Associations with schizophrenia were also found for large deletions on chromosome 15q13.3 and 1q21.1. These associations have not previously been reported, and they remained significant after genome-wide correction. Our results provide strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome-wide and at specific loci. |
|---|---|
| AbstractList | Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90%. Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have been identified in individual patients with schizophrenia and also in neurodevelopmental disorders, but large-scale genome-wide surveys have not been performed. Here we report a genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high-density microarrays. For CNVs that were observed in less than 1% of the sample and were more than 100 kilobases in length, the total burden is increased 1.15-fold in patients with schizophrenia in comparison with controls. This effect was more pronounced for rarer, single-occurrence CNVs and for those that involved genes as opposed to those that did not. As expected, deletions were found within the region critical for velo-cardio- facial syndrome, which includes psychotic symptoms in 30% of patients. Associations with schizophrenia were also found for large deletions on chromosome 15q13.3 and 1q21.1. These associations have not previously been reported, and they remained significant after genome-wide correction. Our results provide strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome-wide and at specific loci. Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90% (ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have been identified in individual patients with schizophrenia and also in neurodevelopmental disorders, but large-scale genome-wide surveys have not been performed. Here we report a genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high-density microarrays. For CNVs that were observed in less than 1% of the sample and were more than 100 kilobases in length, the total burden is increased 1.15-fold in patients with schizophrenia in comparison with controls. This effect was more pronounced for rarer, single-occurrence CNVs and for those that involved genes as opposed to those that did not. As expected, deletions were found within the region critical for velo-cardio-facial syndrome, which includes psychotic symptoms in 30% of patients. Associations with schizophrenia were also found for large deletions on chromosome 15q13.3 and 1q21.1. These associations have not previously been reported, and they remained significant after genome-wide correction. Our results provide strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome-wide and at specific loci. [PUBLICATION ABSTRACT] Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90% (ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have been identified in individual patients with schizophrenia and also in neurodevelopmental disorders, but large-scale genome-wide surveys have not been performed. Here we report a genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high-density microarrays. For CNVs that were observed in less than 1% of the sample and were more than 100 kilobases in length, the total burden is increased 1.15-fold in patients with schizophrenia in comparison with controls. This effect was more pronounced for rarer, single-occurrence CNVs and for those that involved genes as opposed to those that did not. As expected, deletions were found within the region critical for velo-cardio-facial syndrome, which includes psychotic symptoms in 30% of patients. Associations with schizophrenia were also found for large deletions on chromosome 15q13.3 and 1q21.1. These associations have not previously been reported, and they remained significant after genome-wide correction. Our results provide strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome-wide and at specific loci. The genetics of schizophrenia The genetics of schizophrenia and other mental disorders are complex and poorly understood, and made even harder to study because reduced reproduction rates result in negative selection pressure on risk alleles. To date, some copy number variations have been linked to schizophrenia but the studies have been relatively small. Now two independent large-scale genome-wide studies of thousands of patients and controls by two international consortia confirm a previously identified locus but also reveal novel associations. In the first study, a collaboration between SGENE and partners, de novo (spontaneous) copy number variants are reported on chromosomes 1 and 15. In the second study, by the International Schizophrenia Consortium, deletions were also reported on these chromosomes, as was greater overall frequency of copy number variation in the genome. The genetics of schizophrenia and other mental disorders are complex and poorly understood, and made even harder to study due to reduced reproduction resulting in negative selection pressure on risk alleles. Two independent large-scale genome wide studies of thousands of patients and controls by two international consortia confirm a previously identified locus, but also reveal novel associations. In this study, deletions were reported on chromosomes 1 and 15, as well as a greater overall frequency of copy number variation in the genome. Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73–90% (ref. 1 ). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have been identified in individual patients with schizophrenia 2 , 3 , 4 , 5 , 6 , 7 and also in neurodevelopmental disorders 8 , 9 , 10 , 11 , but large-scale genome-wide surveys have not been performed. Here we report a genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high-density microarrays. For CNVs that were observed in less than 1% of the sample and were more than 100 kilobases in length, the total burden is increased 1.15-fold in patients with schizophrenia in comparison with controls. This effect was more pronounced for rarer, single-occurrence CNVs and for those that involved genes as opposed to those that did not. As expected, deletions were found within the region critical for velo-cardio-facial syndrome, which includes psychotic symptoms in 30% of patients 12 . Associations with schizophrenia were also found for large deletions on chromosome 15q13.3 and 1q21.1. These associations have not previously been reported, and they remained significant after genome-wide correction. Our results provide strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome-wide and at specific loci. Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73 - 90% ( ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants ( CNVs) have been identified in individual patients with schizophrenia(2-7) and also in neurodevelopmental disorders(8-11), but large- scale genome- wide surveys have not been performed. Here we report a genome- wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high- density microarrays. For CNVs that were observed in less than 1% of the sample and were more than 100 kilobases in length, the total burden is increased 1.15- fold in patients with schizophrenia in comparison with controls. This effect was more pronounced for rarer, single- occurrence CNVs and for those that involved genes as opposed to those that did not. As expected, deletions were found within the region critical for velo- cardio- facial syndrome, which includes psychotic symptoms in 30% of patients(12). Associations with schizophrenia were also found for large deletions on chromosome 15q13.3 and 1q21.1. These associations have not previously been reported, and they remained significant after genome- wide correction. Our results provide strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome- wide and at specific loci. |
| Audience | Academic |
| Author | Stone, Jennifer L. Craddock, Nick J. Kirov, George K. Purcell, Shaun M. O'Donovan, Michael C. McQuillin, Andrew Blackwood, Douglas H. R. Sullivan, Patrick F. Gill, Michael Corvin, Aiden Gurling, Hugh Ruderfer, Douglas M. Owen, Michael J. Sklar, Pamela St Clair, David Lichtenstein, Paul Hultman, Christina M. Pato, Carlos N. |
| Author_xml | – sequence: 1 givenname: Jennifer L. surname: Stone fullname: Stone, Jennifer L. – sequence: 2 givenname: Michael C. surname: O'Donovan fullname: O'Donovan, Michael C. – sequence: 3 givenname: Hugh surname: Gurling fullname: Gurling, Hugh – sequence: 4 givenname: George K. surname: Kirov fullname: Kirov, George K. – sequence: 5 givenname: Douglas H. R. surname: Blackwood fullname: Blackwood, Douglas H. R. – sequence: 6 givenname: Aiden surname: Corvin fullname: Corvin, Aiden – sequence: 7 givenname: Nick J. surname: Craddock fullname: Craddock, Nick J. – sequence: 8 givenname: Michael surname: Gill fullname: Gill, Michael – sequence: 9 givenname: Christina M. surname: Hultman fullname: Hultman, Christina M. organization: Psykiatri, Akademiska sjukhuset – sequence: 10 givenname: Paul surname: Lichtenstein fullname: Lichtenstein, Paul – sequence: 11 givenname: Andrew surname: McQuillin fullname: McQuillin, Andrew – sequence: 12 givenname: Carlos N. surname: Pato fullname: Pato, Carlos N. – sequence: 13 givenname: Douglas M. surname: Ruderfer fullname: Ruderfer, Douglas M. – sequence: 14 givenname: Michael J. surname: Owen fullname: Owen, Michael J. – sequence: 15 givenname: David surname: St Clair fullname: St Clair, David – sequence: 16 givenname: Patrick F. surname: Sullivan fullname: Sullivan, Patrick F. – sequence: 17 givenname: Pamela surname: Sklar fullname: Sklar, Pamela – sequence: 18 givenname: Shaun M. surname: Purcell fullname: Purcell, Shaun M. |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20618806$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/18668038$$D View this record in MEDLINE/PubMed https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109079$$DView record from Swedish Publication Index http://kipublications.ki.se/Default.aspx?queryparsed=id:117547471$$DView record from Swedish Publication Index |
| BookMark | eNp9k8uP0zAQhyO0iH3AiTsKSIAQZLETx44vSFV5LVqBtCxwtFxnkno3sbN2wuuvx1VLm6IW-RBr5vvNTGY8x9GBsQai6D5GpxhlxUsj-8EBYmnGb0VHmDCaEFqwg-gIobRIUJHRw-jY-yuEUI4ZuRMd4oLSImiPog8X0kGs5s621ttWNnEJDfTaGh9LU8bl0DVayaVBG-VAeoid9texrWKv5vq37eYOjJZ3o9uVbDzcW31Poi9v31xO3yfnn96dTSfnieI56RMMVUFDYUUBPCUkz6sCyjyUTxmFnFIsqUzLWaYkSnPGZmSWFoRyxkpcwqzC2UmULOP6H9ANM9E53Ur3S1ipxcp0HW4gcpoGWeD5Xr5zttyI_goxZjlhhC1yvdirfa2_ToR1tRgGgRFHjAf81RIPbAulAtM72Wxn3PIYPRe1_S4yjsNfLmp9ugrg7M0Avhet9gqaRhqwgxeMZCQ0LcsD-eS_ZIo4SxFZgI_-Aa_s4EyYkFj4U8ZTvulpLRsQ2lQ2lKdqMBCqDM-t0sE8wWFonLNiFHSLV52-EWPodAcUTgmtVjujPtsSBKaHn30tB-_F2eeLbfb5fnZy-W36cSetnPXeQbWeCUZisUVitEWBfjAe44ZdrU0AHq8A6ZVsKieN0n7NpYiG1IiOnk9wmRrcpve78z5c4kvjOt6Y-QOAekEK |
| CODEN | NATUAS |
| CitedBy_id | crossref_primary_10_1111_bpa_12517 crossref_primary_10_1016_j_biopsych_2012_01_020 crossref_primary_10_1016_j_eurpsy_2013_06_002 crossref_primary_10_1002_ajmg_a_35601 crossref_primary_10_1016_j_biopsych_2016_08_014 crossref_primary_10_1016_j_neuron_2011_09_030 crossref_primary_10_1038_s41398_017_0008_3 crossref_primary_10_1093_schbul_sbp137 crossref_primary_10_1212_WNL_0b013e3181e0f147 crossref_primary_10_1186_s12916_021_02039_9 crossref_primary_10_1016_j_conb_2008_08_010 crossref_primary_10_1042_BST0380445 crossref_primary_10_1038_mp_2009_101 crossref_primary_10_1038_ejhg_2012_165 crossref_primary_10_1038_jhg_2008_7 crossref_primary_10_1016_j_neuint_2010_08_013 crossref_primary_10_1111_bdi_12125 crossref_primary_10_1080_13546800902978417 crossref_primary_10_1016_j_bpsc_2021_11_008 crossref_primary_10_1016_j_neuron_2015_01_010 crossref_primary_10_1016_j_yebeh_2012_07_005 crossref_primary_10_1136_jmedgenet_2013_102064 crossref_primary_10_1038_npp_2014_95 crossref_primary_10_1007_s40473_015_0041_6 crossref_primary_10_3109_10673220903523532 crossref_primary_10_1016_j_neures_2013_10_009 crossref_primary_10_1093_schbul_sbp153 crossref_primary_10_1093_hmg_ddr603 crossref_primary_10_1016_j_biopsych_2009_01_003 crossref_primary_10_1186_s40246_021_00318_3 crossref_primary_10_1016_j_schres_2016_11_031 crossref_primary_10_1016_j_schres_2011_01_011 crossref_primary_10_1186_s12864_018_4573_5 crossref_primary_10_1007_s10803_016_2758_9 crossref_primary_10_1007_s11910_009_0029_2 crossref_primary_10_1038_mp_2016_98 crossref_primary_10_1038_ng_481 crossref_primary_10_1038_srep25986 crossref_primary_10_1371_journal_pgen_1003333 crossref_primary_10_1016_j_neuropharm_2011_01_024 crossref_primary_10_1371_journal_pgen_1003332 crossref_primary_10_1371_journal_pgen_1001154 crossref_primary_10_1016_j_jns_2009_04_034 crossref_primary_10_1186_s12888_015_0594_7 crossref_primary_10_1016_j_neulet_2009_11_003 crossref_primary_10_1038_ng_3725 crossref_primary_10_1097_YPG_0000000000000275 crossref_primary_10_1016_S0140_6736_21_01730_X crossref_primary_10_1016_j_biopsych_2014_05_011 crossref_primary_10_1097_YPG_0000000000000032 crossref_primary_10_3390_genes3040759 crossref_primary_10_1038_npp_2014_65 crossref_primary_10_1002_ajmg_a_33692 crossref_primary_10_1055_s_0029_1223481 crossref_primary_10_1016_j_neuropharm_2011_01_030 crossref_primary_10_1038_mp_2016_88 crossref_primary_10_1038_ng_474 crossref_primary_10_1186_1471_2105_12_205 crossref_primary_10_1016_j_biopsych_2011_07_011 crossref_primary_10_1017_S0033291709991139 crossref_primary_10_1038_jhg_2014_13 crossref_primary_10_1093_schbul_sbn187 crossref_primary_10_1097_YPG_0b013e328353ae3d crossref_primary_10_1007_s12041_023_01427_9 crossref_primary_10_1038_mp_2017_115 crossref_primary_10_2337_db10_0192 crossref_primary_10_1371_journal_pone_0016339 crossref_primary_10_3390_genes14030689 crossref_primary_10_3389_fncel_2022_939143 crossref_primary_10_1038_nrg2612 crossref_primary_10_1038_ng_237 crossref_primary_10_1111_bph_13938 crossref_primary_10_1007_s12016_009_8170_x crossref_primary_10_1002_em_21943 crossref_primary_10_1007_s11126_021_09937_4 crossref_primary_10_1126_science_aaa8954 crossref_primary_10_1016_j_nicl_2016_08_020 crossref_primary_10_1371_journal_pone_0089776 crossref_primary_10_1038_mp_2009_149 crossref_primary_10_1101_gr_107680_110 crossref_primary_10_1038_ng_3903 crossref_primary_10_1017_S1462399411001955 crossref_primary_10_1186_gb_2012_13_1_237 crossref_primary_10_1002_ana_22673 crossref_primary_10_1186_1866_1955_4_15 crossref_primary_10_1016_j_psc_2009_12_005 crossref_primary_10_1016_j_psc_2009_12_003 crossref_primary_10_1016_j_schres_2011_01_001 crossref_primary_10_3389_fncir_2021_769969 crossref_primary_10_1038_tp_2012_76 crossref_primary_10_1007_s10803_012_1713_7 crossref_primary_10_1097_YPG_0b013e32833a9b7a crossref_primary_10_1371_journal_pone_0023087 crossref_primary_10_1016_j_psc_2009_12_006 crossref_primary_10_1186_s13041_017_0335_6 crossref_primary_10_1097_CCO_0b013e328333dca4 crossref_primary_10_1016_j_intell_2013_11_005 crossref_primary_10_1007_s00439_012_1261_4 crossref_primary_10_1002_ajmg_c_31327 crossref_primary_10_1186_1471_2164_14_191 crossref_primary_10_1002_em_21722 crossref_primary_10_1038_s41398_018_0216_5 crossref_primary_10_1093_hmg_ddv199 crossref_primary_10_1111_j_1469_1809_2011_00660_x crossref_primary_10_1016_j_cell_2013_06_049 crossref_primary_10_1016_j_gde_2009_04_003 crossref_primary_10_1093_bib_bbaa381 crossref_primary_10_1038_srep39941 crossref_primary_10_1007_s00406_009_0025_1 crossref_primary_10_1002_wps_20274 crossref_primary_10_1111_epi_13748 crossref_primary_10_1093_hmg_ddp413 crossref_primary_10_1016_j_neuroscience_2009_03_080 crossref_primary_10_1038_mp_2015_7 crossref_primary_10_1371_journal_pone_0135931 crossref_primary_10_1073_pnas_1802610115 crossref_primary_10_1111_j_1752_4571_2010_00156_x crossref_primary_10_1016_j_schres_2016_12_012 crossref_primary_10_1038_ejhg_2012_194 crossref_primary_10_1016_j_coph_2011_08_003 crossref_primary_10_1016_S1016_3190_09_60039_2 crossref_primary_10_1093_bioinformatics_btp606 crossref_primary_10_1038_npp_2014_290 crossref_primary_10_1111_epi_12078 crossref_primary_10_1016_S0140_6736_09_60995_8 crossref_primary_10_1016_j_biopsych_2013_08_014 crossref_primary_10_1038_mp_2008_133 crossref_primary_10_1038_mp_2008_135 crossref_primary_10_1002_ajmg_b_32148 crossref_primary_10_1016_j_schres_2014_01_038 crossref_primary_10_1186_1749_8104_9_6 crossref_primary_10_1002_ajmg_b_31063 crossref_primary_10_1186_1741_7007_9_77 crossref_primary_10_1016_j_schres_2014_01_030 crossref_primary_10_1038_mp_2008_131 crossref_primary_10_1186_1741_7007_9_76 crossref_primary_10_1038_tp_2017_106 crossref_primary_10_1016_j_neuroimage_2009_11_030 crossref_primary_10_31766_revpsij_v35n4a7 crossref_primary_10_1002_ajmg_a_35214 crossref_primary_10_1177_0269881116653109 crossref_primary_10_1371_journal_pone_0104396 crossref_primary_10_1002_ajmg_b_31045 crossref_primary_10_1002_ajmg_b_32135 crossref_primary_10_1016_j_biopsych_2022_04_003 crossref_primary_10_1038_mp_2008_126 crossref_primary_10_1371_journal_pone_0064035 crossref_primary_10_3389_fgene_2020_00577 crossref_primary_10_1146_annurev_med_100708_204735 crossref_primary_10_1038_mp_2015_107 crossref_primary_10_1038_s41380_017_0010_4 crossref_primary_10_1002_ana_22645 crossref_primary_10_1038_ng_415 crossref_primary_10_1007_s11689_011_9089_0 crossref_primary_10_1016_j_jaac_2013_02_008 crossref_primary_10_1371_journal_pgen_1001318 crossref_primary_10_1111_j_1747_0803_2011_00582_x crossref_primary_10_1016_j_pharmthera_2008_11_002 crossref_primary_10_1111_j_1399_0004_2009_01231_2_x crossref_primary_10_1093_schbul_sbx006 crossref_primary_10_1111_j_1365_2796_2009_02096_x crossref_primary_10_1016_j_gde_2013_02_015 crossref_primary_10_1101_gr_086660_108 crossref_primary_10_1016_j_biopsych_2012_10_013 crossref_primary_10_1038_mp_2008_108 crossref_primary_10_1159_000452416 crossref_primary_10_7554_eLife_58430 crossref_primary_10_1371_journal_pone_0270506 crossref_primary_10_1038_nature08979 crossref_primary_10_1016_j_cell_2008_12_044 crossref_primary_10_1016_j_ando_2009_07_003 crossref_primary_10_1038_nrg3786 crossref_primary_10_1038_npp_2013_293 crossref_primary_10_1093_bfgp_elv014 crossref_primary_10_1371_journal_pone_0128369 crossref_primary_10_1016_j_bcp_2011_06_018 crossref_primary_10_1016_j_tins_2008_11_002 crossref_primary_10_1002_ajmg_b_32121 crossref_primary_10_3389_fgene_2018_00434 crossref_primary_10_1016_j_conb_2012_04_007 crossref_primary_10_1093_bfgp_elv017 crossref_primary_10_1016_j_neuroscience_2009_04_038 crossref_primary_10_1074_jbc_M112_393439 crossref_primary_10_1017_S0954579412000740 crossref_primary_10_1371_journal_pgen_1003797 crossref_primary_10_1002_ajmg_b_32189 crossref_primary_10_1016_S2173_5050_10_70013_3 crossref_primary_10_1016_j_biopsych_2015_02_025 crossref_primary_10_3390_genes11050525 crossref_primary_10_1038_srep19088 crossref_primary_10_1016_j_jaac_2010_06_007 crossref_primary_10_1016_j_schres_2011_11_004 crossref_primary_10_1016_j_ajhg_2011_11_025 crossref_primary_10_1016_j_ajhg_2009_03_008 crossref_primary_10_1111_j_1749_6632_2008_03608_x crossref_primary_10_1016_j_psychres_2012_01_016 crossref_primary_10_1016_j_tig_2008_12_002 crossref_primary_10_1097_GIM_0b013e3181e3914a crossref_primary_10_1038_nature09884 crossref_primary_10_1101_gr_083501_108 crossref_primary_10_1371_journal_pgen_1002692 crossref_primary_10_1002_ajmg_b_31093 crossref_primary_10_1038_srep14613 crossref_primary_10_1038_nn_3276 crossref_primary_10_1038_nrg2437 crossref_primary_10_2139_ssrn_3192031 crossref_primary_10_1212_WNL_0000000000001345 crossref_primary_10_1586_ern_12_145 crossref_primary_10_1016_j_tins_2008_12_005 crossref_primary_10_1038_nature07458 crossref_primary_10_1093_hmg_ddu025 crossref_primary_10_1586_erm_09_59 crossref_primary_10_1038_nature07454 crossref_primary_10_1007_s00439_011_1082_x crossref_primary_10_1371_journal_pgen_1002687 crossref_primary_10_1038_mp_2017_161 crossref_primary_10_1016_j_biopsych_2017_11_015 crossref_primary_10_1016_j_psc_2009_10_001 crossref_primary_10_1016_j_gde_2012_02_011 crossref_primary_10_1016_j_jpsychires_2013_07_002 crossref_primary_10_1111_epi_14678 crossref_primary_10_1016_j_biopsych_2011_04_019 crossref_primary_10_1038_mp_2017_166 crossref_primary_10_1007_BF03033803 crossref_primary_10_1523_JNEUROSCI_1312_12_2012 crossref_primary_10_1016_j_pneurobio_2011_05_006 crossref_primary_10_1093_schbul_sbv029 crossref_primary_10_1016_j_biopsych_2013_07_022 crossref_primary_10_1038_npjgenmed_2016_26 crossref_primary_10_1073_pnas_1000274107 crossref_primary_10_1371_journal_pone_0101093 crossref_primary_10_3389_fgene_2014_00053 crossref_primary_10_1093_brain_awp332 crossref_primary_10_1016_j_gde_2020_12_012 crossref_primary_10_1089_cmb_2011_0161 crossref_primary_10_1016_j_neuroscience_2011_07_051 crossref_primary_10_3389_fgene_2022_1009390 crossref_primary_10_1016_j_ejmg_2015_01_002 crossref_primary_10_1002_gepi_22269 crossref_primary_10_1016_j_psychres_2012_01_020 crossref_primary_10_1016_j_schres_2018_07_017 crossref_primary_10_1002_ajmg_b_32156 crossref_primary_10_1002_da_20623 crossref_primary_10_1038_nrneurol_2014_62 crossref_primary_10_1038_nrendo_2012_251 crossref_primary_10_1186_1755_8794_6_10 crossref_primary_10_1002_ajmg_b_32160 crossref_primary_10_1002_ajmg_b_31073 crossref_primary_10_1017_S1461145713000606 crossref_primary_10_1371_journal_pone_0013422 crossref_primary_10_1371_journal_pone_0014511 crossref_primary_10_3389_fnins_2021_614142 crossref_primary_10_4161_epi_6_7_16353 crossref_primary_10_1097_YPG_0b013e32835fe51d crossref_primary_10_1038_mp_2011_8 crossref_primary_10_1111_j_1471_0528_2009_02470_x crossref_primary_10_3389_fncel_2017_00359 crossref_primary_10_1093_cercor_bhaa266 crossref_primary_10_3390_genes12121899 crossref_primary_10_1038_ejhg_2008_189 crossref_primary_10_1016_j_neuropharm_2011_04_011 crossref_primary_10_1111_j_1751_7893_2010_00253_x crossref_primary_10_1016_j_brainres_2009_07_041 crossref_primary_10_1016_j_pharmthera_2014_02_003 crossref_primary_10_1111_gbb_12628 crossref_primary_10_1038_mp_2012_34 crossref_primary_10_1002_ajmg_b_32426 crossref_primary_10_1017_S0033291709991929 crossref_primary_10_1016_j_biopsych_2012_05_035 crossref_primary_10_1016_j_ijdevneu_2016_03_006 crossref_primary_10_1186_1744_9081_6_40 crossref_primary_10_1038_nn_3484 crossref_primary_10_1111_j_1440_1819_2011_02314_x crossref_primary_10_1038_s41398_018_0114_x crossref_primary_10_1038_tp_2016_96 crossref_primary_10_1101_gr_201160_115 crossref_primary_10_1007_s00439_009_0655_4 crossref_primary_10_1093_carcin_bgt344 crossref_primary_10_4236_ojmp_2014_32019 crossref_primary_10_1038_mp_2012_23 crossref_primary_10_1016_j_brainres_2010_03_035 crossref_primary_10_1093_hmg_ddr162 crossref_primary_10_1371_journal_pone_0107705 crossref_primary_10_1016_j_conb_2010_09_008 crossref_primary_10_1016_j_gde_2009_02_008 crossref_primary_10_1093_schbul_sbu045 crossref_primary_10_1186_gm546 crossref_primary_10_16946_kjsr_2014_17_1_12 crossref_primary_10_1016_j_schres_2019_04_026 crossref_primary_10_1159_000438788 crossref_primary_10_5042_jpmh_2010_0324 crossref_primary_10_29001_2073_8552_2021_36_4_37_44 crossref_primary_10_1002_ajmg_b_32406 crossref_primary_10_1016_j_psychres_2012_09_024 crossref_primary_10_3390_ijms241813671 crossref_primary_10_1016_j_biopsych_2015_11_012 crossref_primary_10_1038_mp_2012_58 crossref_primary_10_1016_j_encep_2009_12_003 crossref_primary_10_1080_15622975_2017_1395072 crossref_primary_10_1002_ajmg_b_32402 crossref_primary_10_1038_s41380_023_02103_1 crossref_primary_10_1517_17460440902895446 crossref_primary_10_1093_schbul_sbu016 crossref_primary_10_1186_1471_2105_15_2 crossref_primary_10_3109_09540261_2012_709178 crossref_primary_10_1371_journal_pone_0004906 crossref_primary_10_1002_per_836 crossref_primary_10_1038_s41398_020_0723_z crossref_primary_10_1111_j_1751_7893_2011_00272_x crossref_primary_10_1002_ajmg_b_32637 crossref_primary_10_1016_j_mrrev_2024_108509 crossref_primary_10_1002_ajmg_b_32638 crossref_primary_10_1093_bmb_ldp017 crossref_primary_10_1038_s41398_017_0011_8 crossref_primary_10_1038_ng_909 crossref_primary_10_1038_news_2008_994 crossref_primary_10_1371_journal_pone_0095604 crossref_primary_10_1093_schbul_sbt174 crossref_primary_10_1016_j_ajhg_2022_02_010 crossref_primary_10_1038_tp_2017_159 crossref_primary_10_1016_j_pnpbp_2019_03_009 crossref_primary_10_1016_j_ajhg_2010_07_013 crossref_primary_10_31887_DCNS_2010_12_4_amlindenberg crossref_primary_10_1080_13576500802536439 crossref_primary_10_1038_mp_2012_73 crossref_primary_10_1016_j_celrep_2017_05_002 crossref_primary_10_1016_j_jaac_2010_08_009 crossref_primary_10_1002_ajmg_b_32225 crossref_primary_10_1007_s11357_010_9155_7 crossref_primary_10_1007_s00213_016_4265_2 crossref_primary_10_1089_scd_2019_0217 crossref_primary_10_1093_gbe_evad115 crossref_primary_10_1038_ng_902 crossref_primary_10_1126_science_aad6469 crossref_primary_10_1056_NEJMra1114194 crossref_primary_10_1093_hmg_ddt540 crossref_primary_10_1371_journal_pgen_1002734 crossref_primary_10_1093_brain_awp262 crossref_primary_10_1111_pcn_13474 crossref_primary_10_1038_mp_2012_69 crossref_primary_10_1016_j_biopsych_2014_07_011 crossref_primary_10_1016_j_isci_2021_102894 crossref_primary_10_1007_s11920_011_0183_5 crossref_primary_10_1111_j_1399_0004_2012_01925_x crossref_primary_10_1371_journal_pone_0071434 crossref_primary_10_1016_j_conb_2010_08_009 crossref_primary_10_1038_s41380_019_0517_y crossref_primary_10_4062_biomolther_2016_061 crossref_primary_10_3390_ijms23116118 crossref_primary_10_1038_nrg3240 crossref_primary_10_1126_scisignal_293pe66 crossref_primary_10_1152_physiolgenomics_00157_2009 crossref_primary_10_1016_j_pscychresns_2014_10_006 crossref_primary_10_1002_ajmg_b_32204 crossref_primary_10_1016_j_stem_2014_05_003 crossref_primary_10_3390_ijms22115811 crossref_primary_10_1016_j_ajhg_2010_06_010 crossref_primary_10_1002_ajmg_b_31117 crossref_primary_10_1093_nar_gku345 crossref_primary_10_1007_s40484_018_0137_6 crossref_primary_10_31887_DCNS_2010_12_1_aneed crossref_primary_10_1016_j_gde_2021_05_002 crossref_primary_10_1038_s41398_021_01460_1 crossref_primary_10_1016_j_mgene_2015_07_002 crossref_primary_10_1159_000381585 crossref_primary_10_1016_j_psychres_2016_12_040 crossref_primary_10_1016_j_paid_2011_12_019 crossref_primary_10_1016_j_pnpbp_2020_109973 crossref_primary_10_1016_j_cell_2018_05_046 crossref_primary_10_1002_ajmg_b_32439 crossref_primary_10_1016_j_ajhg_2018_01_006 crossref_primary_10_1371_journal_pgen_1002713 crossref_primary_10_1371_journal_pgen_1000531 crossref_primary_10_1093_hmg_ddq298 crossref_primary_10_1016_j_ygeno_2013_04_004 crossref_primary_10_1093_hmg_dds476 crossref_primary_10_1038_mp_2008_144 crossref_primary_10_1371_journal_pone_0021685 crossref_primary_10_1146_annurev_genom_082509_141640 crossref_primary_10_1038_mp_2008_149 crossref_primary_10_1038_455178a crossref_primary_10_3109_08039488_2011_552734 crossref_primary_10_1016_j_chc_2013_04_005 crossref_primary_10_1093_schbul_sbr197 crossref_primary_10_1517_14728222_2013_736498 crossref_primary_10_1093_schbul_sbs047 crossref_primary_10_2478_s11756_012_0026_9 crossref_primary_10_1186_1744_9081_6_75 crossref_primary_10_1038_ejhg_2014_228 crossref_primary_10_1038_jhg_2010_19 crossref_primary_10_1038_s41598_018_32837_w crossref_primary_10_1111_j_1601_183X_2012_00832_x crossref_primary_10_1186_s13148_016_0171_z crossref_primary_10_1146_annurev_genom_091212_153408 crossref_primary_10_1017_S0033291721000441 crossref_primary_10_1186_s13059_021_02275_5 crossref_primary_10_1016_S1474_4422_13_70011_5 crossref_primary_10_1146_annurev_clinpsy_3_022806_091532 crossref_primary_10_1002_gepi_20636 crossref_primary_10_1097_DBP_0b013e31826052ae crossref_primary_10_1016_j_biopsych_2011_08_009 crossref_primary_10_1016_j_neuron_2017_11_007 crossref_primary_10_1007_s00115_017_0330_2 crossref_primary_10_3389_fpsyt_2019_00270 crossref_primary_10_1093_schbul_sbr161 crossref_primary_10_1159_000324366 crossref_primary_10_1038_s41467_018_05714_3 crossref_primary_10_3390_ijms22179464 crossref_primary_10_1038_s41398_018_0132_8 crossref_primary_10_1093_hmg_ddq009 crossref_primary_10_1038_mp_2014_42 crossref_primary_10_1186_1471_2393_12_61 crossref_primary_10_1016_j_ajhg_2008_12_014 crossref_primary_10_1038_mp_2014_40 crossref_primary_10_1093_nar_gky538 crossref_primary_10_1016_j_conb_2014_12_001 crossref_primary_10_1016_j_euroneuro_2016_07_011 crossref_primary_10_1016_j_pneurobio_2015_09_002 crossref_primary_10_1111_jnc_14970 crossref_primary_10_1038_ng_2565 crossref_primary_10_1016_j_schres_2014_04_004 crossref_primary_10_1586_14737175_9_1_47 crossref_primary_10_1111_j_1467_8624_2012_01757_x crossref_primary_10_1093_schbul_sbq080 crossref_primary_10_1016_j_brainresbull_2011_09_007 crossref_primary_10_1038_tp_2011_16 crossref_primary_10_1073_pnas_1615719114 crossref_primary_10_3109_10673229_2012_694321 crossref_primary_10_1038_tp_2015_151 crossref_primary_10_1186_gm397 crossref_primary_10_1016_j_neubiorev_2013_06_005 crossref_primary_10_1016_j_neuron_2015_11_036 crossref_primary_10_1016_j_schres_2014_04_032 crossref_primary_10_1016_j_jpsychires_2013_10_022 crossref_primary_10_1038_tp_2013_101 crossref_primary_10_1038_ng_3200 crossref_primary_10_1016_j_semcdb_2021_08_007 crossref_primary_10_1093_hmg_ddr340 crossref_primary_10_1038_jhg_2010_55 crossref_primary_10_1002_gepi_20604 crossref_primary_10_1111_j_1755_5949_2010_00155_x crossref_primary_10_1016_j_mcn_2016_01_003 crossref_primary_10_1093_hmg_ddq259 crossref_primary_10_1038_nature08186 crossref_primary_10_1038_nature08185 crossref_primary_10_31887_DCNS_2010_12_1_mnoethen crossref_primary_10_1038_ng1208_1392 crossref_primary_10_1001_jamapsychiatry_2021_3392 crossref_primary_10_1016_j_biopsych_2013_10_028 crossref_primary_10_1371_journal_pgen_1000962 crossref_primary_10_1016_j_nbd_2013_01_011 crossref_primary_10_1371_journal_pone_0037385 crossref_primary_10_1016_j_nicl_2018_10_008 crossref_primary_10_1016_j_pharma_2009_02_009 crossref_primary_10_1111_j_1399_0004_2009_01342_x crossref_primary_10_1186_s13073_017_0472_7 crossref_primary_10_1002_aur_1502 crossref_primary_10_1097_YPG_0b013e3283207ff6 crossref_primary_10_1038_tp_2011_24 crossref_primary_10_1016_j_jpsychires_2019_04_007 crossref_primary_10_1371_journal_pone_0051674 crossref_primary_10_1038_ng_292 crossref_primary_10_1016_j_jpsychores_2009_06_006 crossref_primary_10_1002_dneu_22542 crossref_primary_10_1093_schbul_sbq036 crossref_primary_10_1038_ejhg_2010_191 crossref_primary_10_1002_ajmg_a_33917 crossref_primary_10_1111_acer_12364 crossref_primary_10_1038_s41398_020_0771_4 crossref_primary_10_1111_j_1600_0447_2010_01623_x crossref_primary_10_1038_tp_2011_30 crossref_primary_10_1016_j_pnpbp_2017_12_001 crossref_primary_10_1177_10738584090150010301 crossref_primary_10_1016_j_biopsych_2011_09_034 crossref_primary_10_1124_dmd_109_026856 crossref_primary_10_1016_j_gde_2021_03_004 crossref_primary_10_1016_j_jad_2019_02_028 crossref_primary_10_1093_schbul_sbq004 crossref_primary_10_1016_j_biopsych_2011_09_032 crossref_primary_10_1159_000506858 crossref_primary_10_1016_S0140_6736_10_61192_0 crossref_primary_10_1016_j_fertnstert_2016_11_002 crossref_primary_10_1016_j_neulet_2012_04_037 crossref_primary_10_1007_s10709_011_9577_x crossref_primary_10_1097_01_NT_0000339426_38806_5c crossref_primary_10_1111_cge_12111 crossref_primary_10_1016_j_neuron_2010_10_013 crossref_primary_10_1038_s41380_020_0820_7 crossref_primary_10_1126_scitranslmed_aat6912 crossref_primary_10_1111_gbb_12650 crossref_primary_10_1002_dneu_22567 crossref_primary_10_1371_journal_pone_0007799 crossref_primary_10_1111_pcn_12528 crossref_primary_10_1111_epi_12920 crossref_primary_10_1016_j_neuron_2011_05_002 crossref_primary_10_3109_15622975_2013_838641 crossref_primary_10_1016_j_biopsych_2019_04_031 crossref_primary_10_1016_j_gene_2020_144901 crossref_primary_10_3390_ijms242115818 crossref_primary_10_1038_ng_279 crossref_primary_10_1111_cogs_12230 crossref_primary_10_1016_j_schres_2014_06_016 crossref_primary_10_1038_jhg_2011_108 crossref_primary_10_1093_hmg_ddp311 crossref_primary_10_1007_s12035_011_8183_3 crossref_primary_10_1038_mp_2011_154 crossref_primary_10_1093_schbul_sbp017 crossref_primary_10_1038_s41598_021_93555_4 crossref_primary_10_1038_s41537_019_0072_1 crossref_primary_10_1517_14656566_2016_1149164 crossref_primary_10_1038_mp_2010_107 crossref_primary_10_1093_schbul_sbp020 crossref_primary_10_1097_YPG_0000000000000177 crossref_primary_10_1177_0269881111434623 crossref_primary_10_1097_YPG_0000000000000172 crossref_primary_10_1038_ejhg_2012_287 crossref_primary_10_1093_cercor_bhaa313 crossref_primary_10_1016_j_ajhg_2012_07_004 crossref_primary_10_1111_gbb_12066 crossref_primary_10_1016_j_phrs_2023_106783 crossref_primary_10_1016_j_biopsych_2018_12_009 crossref_primary_10_1038_ejhg_2010_35 crossref_primary_10_1016_j_ajhg_2013_02_006 crossref_primary_10_1073_pnas_0906222107 crossref_primary_10_12688_f1000research_16574_1 crossref_primary_10_31887_DCNS_2010_12_1_ddick crossref_primary_10_1038_srep03807 crossref_primary_10_1073_pnas_1309475110 crossref_primary_10_1016_j_tig_2009_05_005 crossref_primary_10_1007_s11920_017_0807_5 crossref_primary_10_1016_S2215_0366_19_30520_6 crossref_primary_10_1016_j_cell_2012_12_041 crossref_primary_10_1371_journal_pgen_1005403 crossref_primary_10_1016_j_cell_2012_03_028 crossref_primary_10_2174_1567205017666201130111424 crossref_primary_10_1016_j_bbi_2016_11_026 crossref_primary_10_1523_JNEUROSCI_5640_11_2012 crossref_primary_10_1080_15622970902898980 crossref_primary_10_1186_s13073_017_0488_z crossref_primary_10_1038_ejhg_2010_211 crossref_primary_10_1016_S0140_6736_09_60249_X crossref_primary_10_14789_jmj_63_8 crossref_primary_10_2967_jnumed_109_066076 crossref_primary_10_1093_nar_gkw281 crossref_primary_10_1016_j_schres_2009_02_007 crossref_primary_10_1111_gbb_12043 crossref_primary_10_1186_1471_2350_10_144 crossref_primary_10_1016_j_ejmg_2009_08_002 crossref_primary_10_1186_s13059_014_0483_2 crossref_primary_10_1038_mp_2011_144 crossref_primary_10_1002_ajmg_a_35754 crossref_primary_10_3724_SP_J_1206_2008_00881 crossref_primary_10_1016_j_ejmg_2010_03_010 crossref_primary_10_1111_cge_13537 crossref_primary_10_1093_schbul_sbp006 crossref_primary_10_1073_pnas_1114042108 crossref_primary_10_1089_cap_2017_0068 crossref_primary_10_1016_j_ajhg_2012_08_005 crossref_primary_10_1016_j_semcdb_2013_02_003 crossref_primary_10_1002_ajmg_b_32088 crossref_primary_10_1038_s41380_022_01937_5 crossref_primary_10_3389_fgene_2021_728816 crossref_primary_10_1007_s00406_011_0206_6 crossref_primary_10_1017_S0033291712001286 crossref_primary_10_1371_journal_pone_0112745 crossref_primary_10_1002_jcp_30581 crossref_primary_10_1007_s12017_012_8198_6 crossref_primary_10_47102_annals_acadmedsg_V38N5p436 crossref_primary_10_1016_j_ajhg_2012_08_003 crossref_primary_10_1111_j_1399_0004_2010_01456_x crossref_primary_10_1371_journal_pgen_1001097 crossref_primary_10_1016_j_cell_2012_11_052 crossref_primary_10_1586_ern_09_133 crossref_primary_10_1017_S0033291711001607 crossref_primary_10_1038_nature07744 crossref_primary_10_1051_medsci_2009253219 crossref_primary_10_1093_hmg_ddu199 crossref_primary_10_1038_s41398_019_0538_y crossref_primary_10_47102_annals_acadmedsg_V38N5p425 crossref_primary_10_1002_ajpa_23965 crossref_primary_10_1038_srep24327 crossref_primary_10_1016_j_schres_2012_03_013 crossref_primary_10_1146_annurev_genom_091212_153431 crossref_primary_10_3389_fgene_2021_622886 crossref_primary_10_1038_ejhg_2010_221 crossref_primary_10_1080_15513815_2017_1324547 crossref_primary_10_1017_S003329171000070X crossref_primary_10_1016_j_biopsych_2021_11_019 crossref_primary_10_1146_annurev_med_072010_091100 crossref_primary_10_1124_pr_113_008581 crossref_primary_10_1007_s11920_014_0502_8 crossref_primary_10_1038_ejhg_2010_87 crossref_primary_10_1093_hmg_ddn351 crossref_primary_10_1534_g3_111_000174 crossref_primary_10_1016_j_rbmo_2013_09_010 crossref_primary_10_1016_j_schres_2012_10_010 crossref_primary_10_1038_nature09915 crossref_primary_10_1017_S1462399410001390 crossref_primary_10_1073_pnas_1110574108 crossref_primary_10_1111_j_1346_8138_2012_01504_x crossref_primary_10_1007_s11910_012_0266_7 crossref_primary_10_3390_ijms25020946 crossref_primary_10_1002_humu_21398 crossref_primary_10_3389_fneur_2014_00238 crossref_primary_10_1038_ng_327 crossref_primary_10_1080_15622975_2016_1183043 crossref_primary_10_1016_j_bcp_2015_07_018 crossref_primary_10_3390_cells9020366 crossref_primary_10_1038_mp_2011_183 crossref_primary_10_1038_s41380_020_00912_2 crossref_primary_10_3390_ijms17060842 crossref_primary_10_1097_WCO_0b013e328344062f crossref_primary_10_1016_j_ajhg_2018_12_018 crossref_primary_10_1093_hmg_ddx241 crossref_primary_10_1586_ern_11_84 crossref_primary_10_2217_epi_12_20 crossref_primary_10_3109_15622975_2011_565073 crossref_primary_10_1016_j_biopsych_2009_08_034 crossref_primary_10_1016_j_cobeha_2014_07_001 crossref_primary_10_1016_j_nbd_2012_02_016 crossref_primary_10_1002_ajmg_a_34237 crossref_primary_10_1016_j_jpsychires_2010_03_007 crossref_primary_10_1002_cne_24554 crossref_primary_10_1371_journal_pone_0055208 crossref_primary_10_1002_ajmg_b_32266 crossref_primary_10_1073_pnas_0908584106 crossref_primary_10_1093_hmg_ddv253 crossref_primary_10_1016_j_jpsychires_2012_11_007 crossref_primary_10_1016_j_tig_2012_03_002 crossref_primary_10_1038_mp_2009_11 crossref_primary_10_3389_fgene_2022_1084974 crossref_primary_10_1038_ng_302 crossref_primary_10_1016_j_ajhg_2014_09_013 crossref_primary_10_1016_j_schres_2011_06_023 crossref_primary_10_1186_1471_2350_12_154 crossref_primary_10_4236_ojpsych_2013_31008 crossref_primary_10_1016_j_schres_2010_01_023 crossref_primary_10_1016_j_biopsych_2012_06_014 crossref_primary_10_1002_ajhb_21132 crossref_primary_10_1007_s00439_013_1263_x crossref_primary_10_1016_j_cell_2012_02_039 crossref_primary_10_1016_j_amp_2013_01_036 crossref_primary_10_1016_j_ajhg_2010_10_004 crossref_primary_10_1016_j_ajhg_2010_10_007 crossref_primary_10_1016_j_ajhg_2012_05_005 crossref_primary_10_1097_YPG_0b013e328353fb63 crossref_primary_10_1371_journal_pone_0014456 crossref_primary_10_1038_ng_534 crossref_primary_10_1586_erm_11_32 crossref_primary_10_1007_s11920_009_0024_y crossref_primary_10_1016_j_neuropharm_2015_02_006 crossref_primary_10_1371_journal_pgen_1002521 crossref_primary_10_1134_S1019331610030135 crossref_primary_10_1002_ajmg_b_31157 crossref_primary_10_1002_ajmg_b_32005 crossref_primary_10_1038_mp_2010_36 crossref_primary_10_1016_j_schres_2013_09_010 crossref_primary_10_1038_s41398_019_0414_9 crossref_primary_10_1038_s41380_024_02513_9 crossref_primary_10_3389_fnmol_2017_00204 crossref_primary_10_1002_dev_21043 crossref_primary_10_1016_j_pnpbp_2011_01_004 crossref_primary_10_1038_nature08855 crossref_primary_10_1016_j_gde_2011_01_001 crossref_primary_10_1038_mp_2009_53 crossref_primary_10_1002_ajmg_b_32232 crossref_primary_10_1016_j_tins_2020_06_001 crossref_primary_10_1016_j_bcp_2015_06_012 crossref_primary_10_1016_j_gde_2011_01_007 crossref_primary_10_1016_j_jaac_2014_04_022 crossref_primary_10_1093_hmg_ddn307 crossref_primary_10_1101_gr_129635_111 crossref_primary_10_5698_1535_7511_15_4_197 crossref_primary_10_1016_j_ajhg_2012_06_018 crossref_primary_10_1002_ajmg_a_33185 crossref_primary_10_1093_schbul_sbv195 crossref_primary_10_1177_0883073810377658 crossref_primary_10_3390_ijms21197332 crossref_primary_10_1016_j_ajhg_2014_09_005 crossref_primary_10_1016_j_ijdevneu_2010_09_007 crossref_primary_10_1016_j_nlm_2013_06_006 crossref_primary_10_1002_ajmg_a_34034 crossref_primary_10_1002_mgg3_12 crossref_primary_10_1016_j_brainresbull_2010_04_007 crossref_primary_10_1016_j_brainresbull_2010_04_009 crossref_primary_10_1038_ng1008_1151 crossref_primary_10_1016_j_schres_2017_05_011 crossref_primary_10_1101_gr_094987_109 crossref_primary_10_1038_ejhg_2012_81 crossref_primary_10_1038_s41431_023_01379_9 crossref_primary_10_1093_hmg_dds180 crossref_primary_10_1038_s41586_020_2371_0 crossref_primary_10_1146_annurev_genom_082410_101459 crossref_primary_10_1080_15622975_2016_1268715 crossref_primary_10_1016_j_cell_2018_03_051 crossref_primary_10_1016_j_schres_2012_05_015 crossref_primary_10_1016_j_biopsych_2018_07_004 crossref_primary_10_1016_j_fertnstert_2011_01_018 crossref_primary_10_1016_j_psychres_2009_05_014 crossref_primary_10_1007_s40142_015_0078_6 crossref_primary_10_1038_s41467_018_07766_x crossref_primary_10_1038_mp_2009_57 crossref_primary_10_1016_j_cell_2011_09_008 crossref_primary_10_1038_mp_2016_227 crossref_primary_10_1073_pnas_1309324111 crossref_primary_10_1371_journal_pgen_1002334 crossref_primary_10_1002_jnr_23970 crossref_primary_10_1016_j_gde_2013_04_013 crossref_primary_10_1098_rstb_2015_0051 crossref_primary_10_1371_journal_pcbi_1002821 crossref_primary_10_1007_s00127_014_0823_2 crossref_primary_10_1017_S0033291709005431 crossref_primary_10_1038_nrg2554 crossref_primary_10_3390_biom9110680 crossref_primary_10_1242_dmm_003996 crossref_primary_10_1016_j_cell_2011_09_011 crossref_primary_10_1523_JNEUROSCI_3967_14_2015 crossref_primary_10_16946_kjsr_2013_16_1_5 crossref_primary_10_1038_nbt1109_1001 crossref_primary_10_1186_1471_2105_13_130 crossref_primary_10_1002_ajmg_a_35780 crossref_primary_10_1038_mp_2010_7 crossref_primary_10_1038_nrn2841 crossref_primary_10_1017_S0033291717003440 crossref_primary_10_1093_hmg_ddt056 crossref_primary_10_1093_hmg_ddt297 crossref_primary_10_1016_j_cca_2015_07_028 crossref_primary_10_1016_j_neubiorev_2012_07_005 crossref_primary_10_1038_mp_2009_84 crossref_primary_10_3899_jrheum_100758 crossref_primary_10_1017_S0033291708004583 crossref_primary_10_1038_ejhg_2012_6 crossref_primary_10_1016_j_pnpbp_2009_06_001 crossref_primary_10_1111_acel_12407 crossref_primary_10_1002_ajmg_b_32053 crossref_primary_10_1007_s00702_014_1309_9 crossref_primary_10_1038_s41537_020_0097_5 crossref_primary_10_4264_numa_71_369 crossref_primary_10_1111_j_1600_0447_2009_01465_x crossref_primary_10_1016_j_bcp_2010_11_009 crossref_primary_10_1186_1471_2105_13_S7_S12 crossref_primary_10_1038_s41467_023_44116_y crossref_primary_10_1371_journal_pone_0220389 crossref_primary_10_1038_mp_2009_93 crossref_primary_10_1038_mp_2009_96 crossref_primary_10_1016_j_celrep_2024_113946 crossref_primary_10_1002_ajmg_b_32034 crossref_primary_10_1016_j_cell_2018_02_006 crossref_primary_10_1002_stem_762 crossref_primary_10_1038_nn_4267 crossref_primary_10_1097_GIM_0b013e3181f0c5f3 crossref_primary_10_1186_s41065_016_0025_x crossref_primary_10_1002_ajmg_b_31191 crossref_primary_10_1080_01621459_2014_908777 crossref_primary_10_1002_ajmg_b_32285 crossref_primary_10_1038_ng0908_1042 crossref_primary_10_3389_fncel_2015_00386 crossref_primary_10_1093_schbul_sbu064 crossref_primary_10_1016_j_tins_2013_11_005 crossref_primary_10_1111_gbb_12096 crossref_primary_10_3389_fpsyt_2020_593233 crossref_primary_10_1002_ajmg_b_32307 crossref_primary_10_1016_j_ajhg_2011_10_014 crossref_primary_10_1371_journal_pone_0019073 crossref_primary_10_1111_ejn_12489 crossref_primary_10_3389_fgene_2021_699510 crossref_primary_10_1093_schbul_sbab032 crossref_primary_10_1534_g3_112_003061 crossref_primary_10_3390_genes14112054 crossref_primary_10_1038_mp_2011_65 crossref_primary_10_1016_j_pneurobio_2009_10_008 crossref_primary_10_1093_schbul_sbt066 crossref_primary_10_3389_fphar_2022_1005702 crossref_primary_10_1111_j_1467_9868_2012_01028_x crossref_primary_10_1002_ajmg_b_32550 crossref_primary_10_1111_acps_12317 crossref_primary_10_1146_annurev_genom_9_081307_164217 crossref_primary_10_1038_nature08494 crossref_primary_10_1002_ajmg_a_37351 crossref_primary_10_1038_s41467_021_27601_0 crossref_primary_10_1186_s12881_016_0289_z crossref_primary_10_31887_DCNS_2016_18_3_aneed crossref_primary_10_1016_j_ajhg_2011_09_011 crossref_primary_10_1002_aur_1834 crossref_primary_10_31887_DCNS_2010_12_1_jgelernter crossref_primary_10_1016_j_mrrev_2010_04_002 crossref_primary_10_1111_ejn_14436 crossref_primary_10_1111_j_1399_5618_2011_00961_x crossref_primary_10_1093_hmg_ddr283 crossref_primary_10_1128_MCB_00652_15 crossref_primary_10_1186_s13059_016_1041_x crossref_primary_10_1523_JNEUROSCI_2331_12_2013 crossref_primary_10_1007_s00439_021_02291_2 crossref_primary_10_1002_ajmg_b_32781 crossref_primary_10_1093_schbul_sbw102 crossref_primary_10_1016_j_ejmg_2015_10_008 crossref_primary_10_1038_nature12975 crossref_primary_10_1136_jmedgenet_2017_104913 crossref_primary_10_1016_j_neubiorev_2015_01_016 crossref_primary_10_1111_j_1399_0004_2011_01773_x crossref_primary_10_1093_hmg_dds164 crossref_primary_10_1038_456018a crossref_primary_10_1007_s40142_017_0129_2 crossref_primary_10_1038_ejhg_2014_88 crossref_primary_10_1186_1423_0127_17_2 crossref_primary_10_3389_fnhum_2017_00322 crossref_primary_10_1002_ajmg_b_32770 crossref_primary_10_1016_j_ajhg_2008_09_011 crossref_primary_10_1192_bjo_2021_14 crossref_primary_10_1016_j_gene_2013_09_110 crossref_primary_10_1017_S0033291717001970 crossref_primary_10_1093_schbul_sbt041 crossref_primary_10_1017_S1121189X00000944 crossref_primary_10_1016_j_jneuroling_2009_08_003 crossref_primary_10_1016_j_cellsig_2015_06_003 crossref_primary_10_1101_gr_092981_109 crossref_primary_10_1016_j_neubiorev_2011_09_001 crossref_primary_10_1016_j_biopsych_2024_06_015 crossref_primary_10_1101_gr_275488_121 crossref_primary_10_1007_s10519_013_9587_9 crossref_primary_10_1038_s41398_021_01496_3 crossref_primary_10_1038_nature09792 crossref_primary_10_1016_j_schres_2018_02_034 crossref_primary_10_1007_s12268_011_0081_8 crossref_primary_10_1111_age_12402 crossref_primary_10_1186_s11689_016_9175_4 crossref_primary_10_1016_j_ajhg_2009_11_003 crossref_primary_10_1038_mp_2013_127 crossref_primary_10_31887_DCNS_2010_12_3_atiwari crossref_primary_10_1534_genetics_110_125070 crossref_primary_10_1016_j_bbr_2012_07_024 crossref_primary_10_1016_j_brainres_2015_11_009 crossref_primary_10_1074_jbc_M111_276014 crossref_primary_10_1586_eci_11_97 crossref_primary_10_1038_nature09146 crossref_primary_10_1038_s41467_019_08503_8 crossref_primary_10_1016_j_gene_2012_07_008 crossref_primary_10_1038_ejhg_2008_264 crossref_primary_10_1093_hmg_ddq154 crossref_primary_10_1186_s13148_024_01660_8 crossref_primary_10_1212_WNL_0b013e3182a95829 crossref_primary_10_1371_journal_pone_0110198 crossref_primary_10_1007_s00439_016_1705_3 crossref_primary_10_1016_j_biopsych_2011_02_015 crossref_primary_10_1111_gbb_12719 crossref_primary_10_1038_mp_2015_143 crossref_primary_10_1093_schbul_sbr095 crossref_primary_10_1016_j_jaac_2013_01_003 crossref_primary_10_3390_brainsci11020275 crossref_primary_10_1038_s41537_017_0029_1 crossref_primary_10_1002_ajmg_a_36471 crossref_primary_10_1371_journal_pone_0059685 crossref_primary_10_1007_s00415_009_5401_2 crossref_primary_10_1016_S0140_6736_10_61109_9 crossref_primary_10_1007_s10803_011_1184_2 crossref_primary_10_1093_nar_gkv319 crossref_primary_10_3390_ijms23073463 crossref_primary_10_1002_ajmg_b_31231 crossref_primary_10_1002_ajmg_b_32321 crossref_primary_10_31857_S0016675823100107 crossref_primary_10_1016_j_neuropharm_2012_06_040 crossref_primary_10_1159_000450726 crossref_primary_10_1038_nature08035 crossref_primary_10_1016_j_biopsych_2021_09_012 crossref_primary_10_1101_gr_152454_112 crossref_primary_10_7554_eLife_10782 crossref_primary_10_1016_j_rpsm_2010_09_002 crossref_primary_10_1371_journal_pone_0019011 crossref_primary_10_1177_0269881114564096 crossref_primary_10_1017_S0033291717002860 crossref_primary_10_1038_ng_3120 crossref_primary_10_1038_mp_2013_50 crossref_primary_10_1111_j_1460_9568_2011_07875_x crossref_primary_10_1002_ajmg_b_31225 crossref_primary_10_1016_j_pnpbp_2012_04_015 crossref_primary_10_1038_mp_2013_59 crossref_primary_10_1097_YCO_0b013e328325a598 crossref_primary_10_1038_455274b crossref_primary_10_1016_j_mcn_2010_12_014 crossref_primary_10_1016_j_biopsych_2011_12_017 crossref_primary_10_1073_pnas_1012764107 crossref_primary_10_1161_CIRCGENETICS_109_848754 crossref_primary_10_1007_s00439_012_1149_3 crossref_primary_10_1111_j_1399_0004_2010_01374_x crossref_primary_10_1016_j_neuron_2011_11_007 crossref_primary_10_1371_journal_pbio_1000543 crossref_primary_10_7861_clinmedicine_10_6_584 crossref_primary_10_1002_humu_22384 crossref_primary_10_1038_ejhg_2008_228 crossref_primary_10_1093_hmg_ddq366 crossref_primary_10_1016_j_biopsych_2013_05_040 crossref_primary_10_1186_s12864_015_1991_5 crossref_primary_10_2217_14622416_9_12_1809 crossref_primary_10_1016_j_biopsych_2009_07_027 crossref_primary_10_1016_j_tcmj_2012_05_007 crossref_primary_10_1080_21642850_2014_927738 crossref_primary_10_1093_bfgp_elp017 crossref_primary_10_1002_humu_21042 crossref_primary_10_1002_humu_21284 crossref_primary_10_1093_hmg_ddq356 crossref_primary_10_1186_s12915_021_01080_7 crossref_primary_10_1038_nn_3506 crossref_primary_10_1002_emmm_200900007 crossref_primary_10_1007_s12264_014_1494_4 crossref_primary_10_1007_s40142_014_0046_6 crossref_primary_10_1523_JNEUROSCI_0018_15_2015 crossref_primary_10_3928_00485718_20100127_04 crossref_primary_10_1038_s41380_019_0416_2 crossref_primary_10_1155_2016_2173748 crossref_primary_10_1093_brain_awab096 crossref_primary_10_1002_elps_200800755 crossref_primary_10_1016_j_cll_2010_07_007 crossref_primary_10_1093_schbul_sbp079 crossref_primary_10_1101_gr_191338_115 crossref_primary_10_18632_oncotarget_21381 crossref_primary_10_1007_s00018_009_0130_3 crossref_primary_10_1016_j_cll_2010_07_002 crossref_primary_10_1016_j_cll_2010_07_001 crossref_primary_10_1016_j_ejmg_2015_11_004 crossref_primary_10_1016_j_pnpbp_2018_12_019 crossref_primary_10_1073_pnas_1607014113 crossref_primary_10_1016_j_biopsych_2014_11_006 crossref_primary_10_1016_j_psychres_2012_12_009 crossref_primary_10_1093_nar_gks1363 crossref_primary_10_1172_JCI66031 crossref_primary_10_1586_17512433_1_6_773 crossref_primary_10_1016_j_biopsych_2011_01_034 crossref_primary_10_1038_s41380_018_0292_1 crossref_primary_10_1016_j_jad_2019_10_039 crossref_primary_10_1038_mp_2013_98 crossref_primary_10_1093_hmg_ddac115 crossref_primary_10_1093_hmg_ddp043 crossref_primary_10_1126_scitranslmed_3002917 crossref_primary_10_1542_peds_2011_2337 crossref_primary_10_1016_j_biopsych_2010_06_031 crossref_primary_10_1038_mp_2013_92 crossref_primary_10_1371_journal_pone_0052865 crossref_primary_10_1016_j_schres_2015_05_002 crossref_primary_10_1016_j_med_2015_08_004 crossref_primary_10_1371_journal_pone_0077906 crossref_primary_10_1017_S0033291710001510 crossref_primary_10_1051_medsci_20173304010 crossref_primary_10_1016_j_yebeh_2012_09_006 crossref_primary_10_1002_0471142905_hg0723s81 crossref_primary_10_1371_journal_pgen_1003041 crossref_primary_10_1038_mp_2014_172 crossref_primary_10_1093_schbul_sbr031 crossref_primary_10_1002_hipo_20887 crossref_primary_10_1016_j_tins_2009_02_003 crossref_primary_10_1093_schbul_sbr030 crossref_primary_10_1016_j_schres_2019_10_039 crossref_primary_10_1134_S1022795423100101 crossref_primary_10_1093_schbul_sbad066 crossref_primary_10_1016_j_schres_2017_09_025 crossref_primary_10_1016_j_bbr_2009_04_001 crossref_primary_10_1186_2040_2392_4_47 crossref_primary_10_1371_journal_pone_0030860 crossref_primary_10_1002_gepi_21643 crossref_primary_10_1001_jamapsychiatry_2019_0566 crossref_primary_10_1038_s41380_019_0438_9 crossref_primary_10_1002_ajmg_a_62104 crossref_primary_10_1016_j_schres_2013_03_004 crossref_primary_10_1159_000488679 crossref_primary_10_1371_journal_pone_0061365 crossref_primary_10_1371_journal_pone_0088602 crossref_primary_10_3109_09553002_2010_518214 crossref_primary_10_1002_ajmg_b_32502 crossref_primary_10_1038_mp_2012_157 crossref_primary_10_1021_cb500560h crossref_primary_10_3961_jpmph_2009_42_6_356 crossref_primary_10_1242_jcs_137604 crossref_primary_10_1093_femsyr_foaa012 crossref_primary_10_1097_YCO_0b013e32835d8329 crossref_primary_10_1016_j_rcp_2015_11_001 crossref_primary_10_1016_j_neuron_2015_04_022 crossref_primary_10_1007_s12031_017_1003_0 crossref_primary_10_1371_journal_pbio_1000579 crossref_primary_10_4018_jitr_2012010103 crossref_primary_10_1002_gepi_21631 crossref_primary_10_1146_annurev_genom_092010_110715 crossref_primary_10_1016_j_jocn_2015_01_031 crossref_primary_10_1038_jhg_2011_42 crossref_primary_10_1177_2050313X241233184 crossref_primary_10_1146_annurev_genet_102209_163544 crossref_primary_10_1007_s10803_016_2807_4 crossref_primary_10_1016_j_chc_2019_08_007 crossref_primary_10_1016_j_brainres_2010_03_109 crossref_primary_10_1002_wrna_1411 crossref_primary_10_1038_s41380_020_00944_8 crossref_primary_10_1097_BOR_0b013e328336474d crossref_primary_10_1073_pnas_0906080106 crossref_primary_10_1016_j_tig_2009_10_006 crossref_primary_10_1093_hmg_ddp011 crossref_primary_10_1097_WNR_0000000000000838 crossref_primary_10_1016_j_cell_2019_09_021 crossref_primary_10_1016_j_tig_2009_10_004 crossref_primary_10_1038_nn_2647 crossref_primary_10_2217_epi_09_13 crossref_primary_10_1021_pr500656z crossref_primary_10_1038_mp_2012_138 crossref_primary_10_3109_15622975_2010_601760 crossref_primary_10_1111_j_1755_5949_2010_00187_x crossref_primary_10_1126_science_adi5199 crossref_primary_10_1016_j_schres_2010_07_002 crossref_primary_10_1038_clpt_2012_51 crossref_primary_10_1007_s12035_019_01727_1 crossref_primary_10_1016_j_cell_2010_03_032 crossref_primary_10_1096_fj_09_152611 crossref_primary_10_1038_mp_2015_76 crossref_primary_10_1111_j_1601_183X_2011_00710_x crossref_primary_10_1242_dmm_043877 crossref_primary_10_1016_j_pharmthera_2012_08_012 crossref_primary_10_1002_ajmg_a_33810 crossref_primary_10_1371_journal_pone_0111462 crossref_primary_10_1093_schbul_sbq135 crossref_primary_10_1093_schbul_sbad028 crossref_primary_10_1038_mp_2017_19 crossref_primary_10_1111_cge_12242 crossref_primary_10_1016_j_ejmg_2015_12_010 crossref_primary_10_1007_s00439_009_0703_0 crossref_primary_10_1007_s10897_013_9685_0 crossref_primary_10_1038_s41380_023_01978_4 crossref_primary_10_1080_00949655_2020_1732379 crossref_primary_10_1016_j_npbr_2014_11_003 crossref_primary_10_1016_j_brainresbull_2009_08_018 |
| Cites_doi | 10.1126/science.1138659 10.1016/S0168-9525(98)01555-8 10.1002/ajmg.a.32249 10.1093/hmg/ddi489 10.1126/science.288.5466.678 10.1086/318788 10.1093/hmg/9.4.489 10.1016/S0074-7742(06)73001-X 10.1016/j.cell.2007.11.037 10.1016/j.neuron.2006.09.027 10.1086/519795 10.1038/ng1862 10.1002/ajmg.b.30306 10.1001/archpsyc.60.12.1187 10.1056/NEJMoa075974 10.1016/j.bbrc.2006.03.156 10.1016/S0168-9525(02)02592-1 10.1016/S0166-2236(96)10022-9 10.1126/science.1155174 10.1038/ng.93 10.1073/pnas.94.2.587 10.1016/j.ajhg.2007.12.009 10.1073/pnas.92.17.7612 10.1002/ajmg.1549 10.1093/hmg/ddm323 10.1038/sj.mp.4002049 10.1101/gr.5986507 10.1038/nature07229 |
| ContentType | Journal Article |
| Contributor | Holmans, Peter A Fraser, Gillian Thelander, Emma F Pickard, Ben Puri, Vinay Krasucki, Robert Walker, Nicholas Gurling, Hugh St Clair, David Datta, Susmita O'Donovan, Michael C Pato, Michele T Visscher, Peter M Ruderfer, Douglas M Choudhury, Khalid Toncheva, Draga Pato, Carlos N Sullivan, Patrick F Daly, Mark J Van Beck, Margaret Craddock, Nick J Blackwood, Douglas H R Muir, Walter J Hultman, Christina M Sklar, Pamela Lichtenstein, Paul Kwan, Soh Leh Purcell, Shaun M Stone, Jennifer L Lawrence, Jacob Scolnick, Edward M McGhee, Kevin A McQuillin, Andrew Macgregor, Stuart Pimm, Jonathan Curtis, David O'Dushlaine, Colm T Milanova, Vihra Kirov, George K Maclean, Alan W Norton, N Korn, Joshua Owen, Michael J Morris, Derek W Kenny, Elaine Waddington, John L Georgieva, Lucy Williams, Nigel M Nikolov, Ivan Gill, Michael Thirumalai, Srinivasa Bass, Nicholas Corvin, Aiden Malloy, Pat Williams, H Sullivan, Patrick Quested, Digby Crombie, Caroline |
| Contributor_xml | – sequence: 1 givenname: Jennifer L surname: Stone fullname: Stone, Jennifer L – sequence: 2 givenname: Michael C surname: O'Donovan fullname: O'Donovan, Michael C – sequence: 3 givenname: Hugh surname: Gurling fullname: Gurling, Hugh – sequence: 4 givenname: George K surname: Kirov fullname: Kirov, George K – sequence: 5 givenname: Douglas H R surname: Blackwood fullname: Blackwood, Douglas H R – sequence: 6 givenname: Aiden surname: Corvin fullname: Corvin, Aiden – sequence: 7 givenname: Nick J surname: Craddock fullname: Craddock, Nick J – sequence: 8 givenname: Michael surname: Gill fullname: Gill, Michael – sequence: 9 givenname: Christina M surname: Hultman fullname: Hultman, Christina M – sequence: 10 givenname: Paul surname: Lichtenstein fullname: Lichtenstein, Paul – sequence: 11 givenname: Andrew surname: McQuillin fullname: McQuillin, Andrew – sequence: 12 givenname: Carlos N surname: Pato fullname: Pato, Carlos N – sequence: 13 givenname: Douglas M surname: Ruderfer fullname: Ruderfer, Douglas M – sequence: 14 givenname: Michael J surname: Owen fullname: Owen, Michael J – sequence: 15 givenname: David surname: St Clair fullname: St Clair, David – sequence: 16 givenname: Patrick F surname: Sullivan fullname: Sullivan, Patrick F – sequence: 17 givenname: Pamela surname: Sklar fullname: Sklar, Pamela – sequence: 18 givenname: Shaun M surname: Purcell fullname: Purcell, Shaun M – sequence: 19 givenname: Joshua surname: Korn fullname: Korn, Joshua – sequence: 20 givenname: Stuart surname: Macgregor fullname: Macgregor, Stuart – sequence: 21 givenname: Derek W surname: Morris fullname: Morris, Derek W – sequence: 22 givenname: Colm T surname: O'Dushlaine fullname: O'Dushlaine, Colm T – sequence: 23 givenname: Mark J surname: Daly fullname: Daly, Mark J – sequence: 24 givenname: Peter M surname: Visscher fullname: Visscher, Peter M – sequence: 25 givenname: Peter A surname: Holmans fullname: Holmans, Peter A – sequence: 26 givenname: Edward M surname: Scolnick fullname: Scolnick, Edward M – sequence: 27 givenname: Nigel M surname: Williams fullname: Williams, Nigel M – sequence: 28 givenname: Lucy surname: Georgieva fullname: Georgieva, Lucy – sequence: 29 givenname: Ivan surname: Nikolov fullname: Nikolov, Ivan – sequence: 30 givenname: N surname: Norton fullname: Norton, N – sequence: 31 givenname: H surname: Williams fullname: Williams, H – sequence: 32 givenname: Draga surname: Toncheva fullname: Toncheva, Draga – sequence: 33 givenname: Vihra surname: Milanova fullname: Milanova, Vihra – sequence: 34 givenname: Emma F surname: Thelander fullname: Thelander, Emma F – sequence: 35 givenname: Patrick surname: Sullivan fullname: Sullivan, Patrick – sequence: 36 givenname: Elaine surname: Kenny fullname: Kenny, Elaine – sequence: 37 givenname: John L surname: Waddington fullname: Waddington, John L – sequence: 38 givenname: Khalid surname: Choudhury fullname: Choudhury, Khalid – sequence: 39 givenname: Susmita surname: Datta fullname: Datta, Susmita – sequence: 40 givenname: Jonathan surname: Pimm fullname: Pimm, Jonathan – sequence: 41 givenname: Srinivasa surname: Thirumalai fullname: Thirumalai, Srinivasa – sequence: 42 givenname: Vinay surname: Puri fullname: Puri, Vinay – sequence: 43 givenname: Robert surname: Krasucki fullname: Krasucki, Robert – sequence: 44 givenname: Jacob surname: Lawrence fullname: Lawrence, Jacob – sequence: 45 givenname: Digby surname: Quested fullname: Quested, Digby – sequence: 46 givenname: Nicholas surname: Bass fullname: Bass, Nicholas – sequence: 47 givenname: David surname: Curtis fullname: Curtis, David – sequence: 48 givenname: Caroline surname: Crombie fullname: Crombie, Caroline – sequence: 49 givenname: Gillian surname: Fraser fullname: Fraser, Gillian – sequence: 50 givenname: Soh Leh surname: Kwan fullname: Kwan, Soh Leh – sequence: 51 givenname: Nicholas surname: Walker fullname: Walker, Nicholas – sequence: 52 givenname: Walter J surname: Muir fullname: Muir, Walter J – sequence: 53 givenname: Kevin A surname: McGhee fullname: McGhee, Kevin A – sequence: 54 givenname: Ben surname: Pickard fullname: Pickard, Ben – sequence: 55 givenname: Pat surname: Malloy fullname: Malloy, Pat – sequence: 56 givenname: Alan W surname: Maclean fullname: Maclean, Alan W – sequence: 57 givenname: Margaret surname: Van Beck fullname: Van Beck, Margaret – sequence: 58 givenname: Michele T surname: Pato fullname: Pato, Michele T |
| Copyright | Macmillan Publishers Limited. All rights reserved 2008 2008 INIST-CNRS COPYRIGHT 2008 Nature Publishing Group Copyright Nature Publishing Group Sep 11, 2008 |
| Copyright_xml | – notice: Macmillan Publishers Limited. All rights reserved 2008 – notice: 2008 INIST-CNRS – notice: COPYRIGHT 2008 Nature Publishing Group – notice: Copyright Nature Publishing Group Sep 11, 2008 |
| CorporateAuthor | International Schizophrenia Consortium The International Schizophrenia Consortium |
| CorporateAuthor_xml | – sequence: 0 name: The International Schizophrenia Consortium – name: International Schizophrenia Consortium |
| DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION ATWCN 3V. 7QG 7QL 7QP 7QR 7RV 7SN 7SS 7ST 7T5 7TG 7TK 7TM 7TO 7U9 7X2 7X7 7XB 88A 88E 88G 88I 8AF 8AO 8C1 8FD 8FE 8FG 8FH 8FI 8FJ 8FK 8G5 ABJCF ABUWG AFKRA ARAPS ATCPS AZQEC BBNVY BEC BENPR BGLVJ BHPHI BKSAR C1K CCPQU D1I DWQXO FR3 FYUFA GHDGH GNUQQ GUQSH H94 HCIFZ K9. KB. KB0 KL. L6V LK8 M0K M0S M1P M2M M2O M2P M7N M7P M7S MBDVC NAPCQ P5Z P62 P64 PATMY PCBAR PDBOC PQEST PQQKQ PQUKI PSYQQ PTHSS PYCSY Q9U R05 RC3 S0X SOI 7SC 7SP 7SR 7TB 7U5 8BQ F28 JG9 JQ2 KR7 L7M L~C L~D 5PM ADTPV AOWAS DF2 D8T ZZAVC |
| DOI | 10.1038/nature07239 |
| DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Gale In Context: Middle School ProQuest Central (Corporate) Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Calcium & Calcified Tissue Abstracts Chemoreception Abstracts Nursing & Allied Health Database (ProQuest) Ecology Abstracts Entomology Abstracts (Full archive) Environment Abstracts Immunology Abstracts Meteorological & Geoastrophysical Abstracts Neurosciences Abstracts Nucleic Acids Abstracts Oncogenes and Growth Factors Abstracts Virology and AIDS Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Biology Database (Alumni Edition) Medical Database (Alumni Edition) Psychology Database (Alumni) Science Database (Alumni Edition) STEM Database ProQuest Pharma Collection Public Health Database (Proquest) Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni Edition) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest Central Advanced Technologies & Aerospace Collection Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection eLibrary ProQuest Central Technology Collection Natural Science Collection Earth, Atmospheric & Aquatic Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Materials Science Collection ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Research Library Prep AIDS and Cancer Research Abstracts SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Materials Science Database Nursing & Allied Health Database (Alumni Edition) Meteorological & Geoastrophysical Abstracts - Academic ProQuest Engineering Collection Biological Sciences Agricultural Science Database Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Psychology Database ProQuest research library Science Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Engineering Database Research Library (Corporate) Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts Environmental Science Database Earth, Atmospheric & Aquatic Science Database Materials Science Collection ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest One Psychology Engineering Collection Environmental Science Collection ProQuest Central Basic University of Michigan Genetics Abstracts SIRS Editorial Environment Abstracts Computer and Information Systems Abstracts Electronics & Communications Abstracts Engineered Materials Abstracts Mechanical & Transportation Engineering Abstracts Solid State and Superconductivity Abstracts METADEX ANTE: Abstracts in New Technology & Engineering Materials Research Database ProQuest Computer Science Collection Civil Engineering Abstracts Advanced Technologies Database with Aerospace Computer and Information Systems Abstracts Academic Computer and Information Systems Abstracts Professional PubMed Central (Full Participant titles) SwePub SwePub Articles SWEPUB Uppsala universitet SWEPUB Freely available online SwePub Articles full text |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Agricultural Science Database ProQuest One Psychology Research Library Prep ProQuest Central Student Oncogenes and Growth Factors Abstracts ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials Nucleic Acids Abstracts elibrary ProQuest AP Science SciTech Premium Collection Environmental Sciences and Pollution Management Health Research Premium Collection Meteorological & Geoastrophysical Abstracts Natural Science Collection Biological Science Collection Chemoreception Abstracts ProQuest Medical Library (Alumni) Engineering Collection Advanced Technologies & Aerospace Collection Engineering Database Virology and AIDS Abstracts ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Earth, Atmospheric & Aquatic Science Database Agricultural Science Collection ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Ecology Abstracts Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection Entomology Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Environmental Science Database ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Calcium & Calcified Tissue Abstracts Meteorological & Geoastrophysical Abstracts - Academic University of Michigan Technology Collection Technology Research Database SIRS Editorial Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College Research Library (Alumni Edition) ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Biology Journals (Alumni Edition) ProQuest Central Earth, Atmospheric & Aquatic Science Collection Genetics Abstracts ProQuest Engineering Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Agricultural & Environmental Science Collection AIDS and Cancer Research Abstracts Materials Science Database ProQuest Research Library ProQuest Materials Science Collection ProQuest Public Health ProQuest Central Basic ProQuest Science Journals ProQuest Nursing & Allied Health Source ProQuest Psychology Journals (Alumni) ProQuest SciTech Collection Advanced Technologies & Aerospace Database ProQuest Medical Library ProQuest Psychology Journals Animal Behavior Abstracts Materials Science & Engineering Collection Immunology Abstracts Environment Abstracts ProQuest Central (Alumni) Materials Research Database Civil Engineering Abstracts Computer and Information Systems Abstracts – Academic Mechanical & Transportation Engineering Abstracts Electronics & Communications Abstracts ProQuest Computer Science Collection Computer and Information Systems Abstracts METADEX Computer and Information Systems Abstracts Professional Engineered Materials Abstracts Solid State and Superconductivity Abstracts Advanced Technologies Database with Aerospace ANTE: Abstracts in New Technology & Engineering |
| DatabaseTitleList | Genetics Abstracts Agricultural Science Database MEDLINE Materials Research Database |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: 8FG name: ProQuest Technology Collection url: https://search.proquest.com/technologycollection1 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Sciences (General) Physics Biology Medicine |
| EISSN | 1476-4687 1476-4679 |
| EndPage | 241 |
| ExternalDocumentID | oai_swepub_ki_se_562977 oai_prod_swepub_kib_ki_se_117547471 oai_DiVA_org_uu_109079 1556382091 A188899785 10_1038_nature07239 18668038 20618806 nature07239 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Multicenter Study Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: Chief Scientist Office – fundername: Medical Research Council – fundername: NIMH NIH HHS grantid: R01 MH077139 – fundername: NIMH NIH HHS grantid: R01 MH071681 – fundername: NHGRI NIH HHS grantid: R01 HG005827 – fundername: NIMH NIH HHS grantid: R01 MH074027 – fundername: NIMH NIH HHS grantid: MH071681 – fundername: NIMH NIH HHS grantid: R01 MH080403 – fundername: NIMH NIH HHS grantid: 2 P50 MH066392-05A1 – fundername: NIMH NIH HHS grantid: MH074027 – fundername: National Institute of Mental Health : NIMH grantid: P50 MH066392 || MH – fundername: National Institute of Mental Health : NIMH grantid: R01 MH071681 || MH – fundername: National Institute of Mental Health : NIMH grantid: R01 MH077139 || MH – fundername: National Institute of Mental Health : NIMH grantid: R01 MH080403 || MH – fundername: National Institute of Mental Health : NIMH grantid: R01 MH074027 || MH |
| GroupedDBID | - 00M 02 07C 08R 0R 0WA 123 186 1AW 1VR 29M 2KS 2XV 39C 3O- 3V. 4 4.4 42X 4R4 53G 55 5RE 68V 69O 6XO 70F 7RV 7X2 7X7 7XC 85S 88 88A 88E 88I 8AF 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ 8G5 8R4 8R5 8WZ 97F 9M8 A6W A7Z A8Z AAEEF AAGJQ AAIKC AAJWC AAPBV AASDW AAYEP AAYOK AAZLF ABAWZ ABDBF ABEFU ABFKR ABFLS ABFSI ABGIJ ABIVO ABJCF ABOCM ABPPZ ABPTK ABUWG ABWJO ABZEH ACGFS ACGOD ACIWK ACNCT ACPRK ACVYA ADBBV ADBIT ADFPY ADYSU AENEX AETEA AFDAS AFFDN AFFNX AFHKK AFKRA AFRAH AGCDD AGEZK AGHTU AGNAY AGSOS AHGBK AHMBA AHSBF AIDAL AIDUJ ALFFA ALMA_UNASSIGNED_HOLDINGS ARAPS ARMCB ARTTT ASPBG ATCPS ATWCN AVRDS AVWKF AXYYD AZFZN AZQEC B-7 B0M BBAFP BBNVY BCR BCU BEC BENPR BES BGLVJ BHPHI BIN BKEYQ BKKNO BKOMP BKSAR BLC BPHCQ BVXVI CJ0 CO CS3 D1I D1J D1K DB5 DO4 DU5 DWQXO DZ E.- E.L EAD EAP EAS EAZ EBC EBD EBO EBS ECC EE. EJD EMB EMF EMH EMK EPL EPS ESE ESN ESX ET EX3 EXGXG F20 F5P FEDTE FQGFK FSGXE FYUFA G0 GJ GNUQQ GUQSH HCIFZ HR HVGLF HZ I-F I-U IAO ICQ IEA IEP IGS IH2 IHR INH INR IOF IPNFZ IPY ISR ITC K6- KB. KM KOO L-9 L6V L7B LK5 LK8 M0K M0L M1P M2M M2O M2P M7P M7R M7S MVM N9A NAPCQ NEJ O9- OBC OES OHT OMK OVD P-O P2P P62 PATMY PCBAR PDBOC PEA PM3 PQEST PQQKQ PQUKI PROAC PSQYO PTHSS PYCSY Q2X R05 RIG RND RNS RNT RNTTT RXW S0X SC5 SHXYY SIXXV SJFOW SJN SNYQT SV3 TAE TAOOD TBHMF TDRGL TH9 TN5 TSG TUS TWZ U1R U5U UKR UMD UQL VQA WH7 WOW X X7L X7M XFK XHC XKW XZ XZL Y6R YAE YCJ YNT YV8 YXB YZZ Z ZA5 ZGI ZHY ZKB ZKG ZR0 ~88 --- --Z -DZ -ET -~X .-4 .55 .CO .GJ .HR .XZ 08P 0R~ 354 41X 6TJ 97L AAHBH AAHTB AAKAB AAKAS AAMNW ABJNI ABLJU ABPEJ ABVXF ACBEA ACBWK ACGFO ACKOT ACMJI ACWUS ADFRT ADUKH ADZCM AFLOW AFRQD AFSHS AGAYW AGHSJ AIYXT ALIPV AMTXH APEBS BDKGC CCPQU EMOBN ESTFP HMCUK HZ~ NEPJS OHH PSYQQ TEORI UIG UKHRP VVN XIH YFH YOC YQT YR2 YYP ZCA ~02 ~7V ~8M ~G0 ~KM 0B8 1CY 1OL 1VW 3EH 41~ 663 79B AAJYS AAVBQ ABTAH ACBNA ACBTR ACTDY ADRHT AFBBN AJUXI FA8 FAC G8K HG6 IQODW J5H LGEZI LOTEE LSO N4W NADUK NXXTH ODYON PV9 QS- R4F RHI SKT TUD UAO UBY UHB USG VOH XOL YJ6 YQI YQJ YV5 YXA YYQ ZCG ZE2 ZY4 AAYZH CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QG 7QL 7QP 7QR 7SN 7SS 7ST 7T5 7TG 7TK 7TM 7TO 7U9 7XB 8FD 8FK C1K FR3 H94 K9. KL. M7N MBDVC P64 Q9U RC3 SOI 36B 5BI AARCD ABCQX AFWHJ AHBCP AHOSX AIBTJ D0L NNMJJ QF4 QM4 QN7 QO4 7SC 7SP 7SR 7TB 7U5 8BQ F28 JG9 JQ2 KR7 L7M L~C L~D 5PM ABDPE ADTPV AOWAS DF2 D8T ZZAVC ABNNU ACRPL ACUHS AGGDT |
| ID | FETCH-LOGICAL-c954t-1ef8602888e924455f8ed5072676e5661a6a2db3ca02577b4b2846977d1debf13 |
| IEDL.DBID | 8FG |
| ISSN | 0028-0836 1476-4687 |
| IngestDate | Mon Dec 16 03:17:01 EST 2024 Wed Oct 30 04:55:35 EDT 2024 Thu Oct 31 04:22:09 EDT 2024 Tue Sep 17 21:28:08 EDT 2024 Wed Dec 04 11:21:52 EST 2024 Wed Dec 04 07:26:56 EST 2024 Thu Oct 10 21:04:16 EDT 2024 Thu Nov 14 22:07:51 EST 2024 Wed Nov 13 14:04:52 EST 2024 Wed Nov 13 00:22:05 EST 2024 Sat Sep 28 21:31:48 EDT 2024 Sat Sep 28 21:08:07 EDT 2024 Fri Dec 06 03:49:21 EST 2024 Wed Oct 16 00:44:53 EDT 2024 Wed Sep 25 09:32:57 EDT 2024 Fri Oct 11 20:46:22 EDT 2024 Tue Jun 15 14:09:15 EDT 2021 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 7210 |
| Keywords | Psychosis Human Duplication Risk factor Deletion Schizophrenia Genetics Genome |
| Language | English |
| License | CC BY 4.0 http://www.springer.com/tdm |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c954t-1ef8602888e924455f8ed5072676e5661a6a2db3ca02577b4b2846977d1debf13 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 Authors are listed at the end of the paper along with their specific contributions. |
| OpenAccessLink | http://kipublications.ki.se/Default.aspx?queryparsed=id:117547471 |
| PMID | 18668038 |
| PQID | 204527929 |
| PQPubID | 40569 |
| PageCount | 5 |
| ParticipantIDs | swepub_primary_oai_swepub_ki_se_562977 swepub_primary_oai_prod_swepub_kib_ki_se_117547471 swepub_primary_oai_DiVA_org_uu_109079 pubmedcentral_primary_oai_pubmedcentral_nih_gov_3912847 proquest_miscellaneous_743424435 proquest_miscellaneous_20972045 proquest_journals_204527929 gale_infotracgeneralonefile_A188899785 gale_infotraccpiq_188899785 gale_infotracacademiconefile_A188899785 gale_incontextgauss_ISR_A188899785 gale_incontextgauss_ATWCN_A188899785 crossref_primary_10_1038_nature07239 pubmed_primary_18668038 pascalfrancis_primary_20618806 springer_journals_10_1038_nature07239 nature_primary_nature07239 |
| ProviderPackageCode | RNTTT ABGIJ AAZLF DB5 L-9 RND RNT AHGBK 70F EE. ~88 |
| PublicationCentury | 2000 |
| PublicationDate | 2008-09-11 |
| PublicationDateYYYYMMDD | 2008-09-11 |
| PublicationDate_xml | – month: 09 year: 2008 text: 2008-09-11 day: 11 |
| PublicationDecade | 2000 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: England |
| PublicationSubtitle | International weekly journal of science |
| PublicationTitle | Nature |
| PublicationTitleAbbrev | Nature |
| PublicationTitleAlternate | Nature |
| PublicationYear | 2008 |
| Publisher | Nature Publishing Group UK Nature Publishing Nature Publishing Group |
| Publisher_xml | – name: Nature Publishing Group UK – name: Nature Publishing – name: Nature Publishing Group |
| References | Kirov, G. (b3) 2008; 17 Shaikh, T. H. (b28) 2007; 17 (b31) 2000 Korn, J. (b15) Moon, H. J. (b7) 2006; 344 Sullivan, P. F., Kendler, K. S., Neale, M. C. (b1) 2003; 60 Weiss, L. A. (b10) 2008; 358 Stankiewicz, P., Lupski, J. R. (b27) 2002; 18 Lee, J. A., Lupski, J. R. (b11) 2006; 52 Flomen, R. H. (b4) 2006; 141 Sebat, J. (b9) 2007; 316 Sharp, A. J. (b24) 2006; 38 Lee, J. A., Carvalho, C. M., Lupski, J. R. A. (b29) 2007; 131 Friedman, J. I. (b5) 2008; 13 Butler, M. G., Fischer, W., Kibiryeva, N., Bittel, D. C. (b21) 2008; 146 Stefansson, H. ( 10.1038/nature07229 b30) Xu, J. (b23) 2001; 105 Gurling, H. M. (b26) 2001; 68 (b32) 2007 Williams, N. M., O'Donovan, M. C., Owen, M. J. (b12) 2006; 73 Wilson, G. M. (b6) 2006; 15 Marshall, C. R. (b8) 2008; 82 Brzustowicz, L. M., Hodgkinson, K. A., Chow, E. W., Honer, W. G., Bassett, A. S. (b25) 2000; 288 Karayiorgou, M. (b19) 1995; 92 Lupski, J. R. (b16) 1998; 14 McCarroll, S. (b13) Sharp, A. J. (b17) 2008; 40 Purcell, S. (b14) 2007; 81 Walsh, T. (b2) 2008; 320 Shaikh, T. H. (b20) 2000; 9 Freedman, R. (b22) 1997; 94 Ross, C. A., Pearlson, G. D. (b18) 1996; 19 Flomen (CR4) 2006; 141 Walsh (CR2) 2008; 320 CR15 Shaikh (CR28) 2007; 17 Lee, Lupski (CR11) 2006; 52 CR13 Brzustowicz, Hodgkinson, Chow, Honer, Bassett (CR25) 2000; 288 CR32 CR31 CR30 Freedman (CR22) 1997; 94 Moon (CR7) 2006; 344 Sharp (CR24) 2006; 38 Wilson (CR6) 2006; 15 Lee, Carvalho, Lupski (CR29) 2007; 131 Gurling (CR26) 2001; 68 Sebat (CR9) 2007; 316 Kirov (CR3) 2008; 17 Ross, Pearlson (CR18) 1996; 19 Butler, Fischer, Kibiryeva, Bittel (CR21) 2008; 146 Lupski (CR16) 1998; 14 Sharp (CR17) 2008; 40 Weiss (CR10) 2008; 358 Sullivan, Kendler, Neale (CR1) 2003; 60 Karayiorgou (CR19) 1995; 92 Xu (CR23) 2001; 105 Stankiewicz, Lupski (CR27) 2002; 18 Marshall (CR8) 2008; 82 Shaikh (CR20) 2000; 9 Friedman (CR5) 2008; 13 Purcell (CR14) 2007; 81 Williams, O’Donovan, Owen (CR12) 2006; 73 21491642 - Nat Rev Genet. 2008 Sep;9(9):654 18784712 - Nature. 2008 Sep 11;455(7210):178-9 BFnature07239_CR32 BFnature07239_CR31 NM Williams (BFnature07239_CR12) 2006; 73 CA Ross (BFnature07239_CR18) 1996; 19 BFnature07239_CR30 LA Weiss (BFnature07239_CR10) 2008; 358 G Kirov (BFnature07239_CR3) 2008; 17 GM Wilson (BFnature07239_CR6) 2006; 15 CR Marshall (BFnature07239_CR8) 2008; 82 BFnature07239_CR15 T Walsh (BFnature07239_CR2) 2008; 320 BFnature07239_CR13 M Karayiorgou (BFnature07239_CR19) 1995; 92 MG Butler (BFnature07239_CR21) 2008; 146 TH Shaikh (BFnature07239_CR20) 2000; 9 AJ Sharp (BFnature07239_CR24) 2006; 38 JA Lee (BFnature07239_CR29) 2007; 131 PF Sullivan (BFnature07239_CR1) 2003; 60 JR Lupski (BFnature07239_CR16) 1998; 14 AJ Sharp (BFnature07239_CR17) 2008; 40 J Sebat (BFnature07239_CR9) 2007; 316 S Purcell (BFnature07239_CR14) 2007; 81 J Xu (BFnature07239_CR23) 2001; 105 LM Brzustowicz (BFnature07239_CR25) 2000; 288 JA Lee (BFnature07239_CR11) 2006; 52 RH Flomen (BFnature07239_CR4) 2006; 141 JI Friedman (BFnature07239_CR5) 2008; 13 R Freedman (BFnature07239_CR22) 1997; 94 P Stankiewicz (BFnature07239_CR27) 2002; 18 HJ Moon (BFnature07239_CR7) 2006; 344 TH Shaikh (BFnature07239_CR28) 2007; 17 HM Gurling (BFnature07239_CR26) 2001; 68 |
| References_xml | – volume: 288 start-page: 678 year: 2000 end-page: 682 ident: b25 publication-title: Science contributor: fullname: Bassett, A. S. – volume: 316 start-page: 445 year: 2007 end-page: 449 ident: b9 publication-title: Science contributor: fullname: Sebat, J. – volume: 15 start-page: 743 year: 2006 end-page: 749 ident: b6 publication-title: Hum. Mol. Genet. contributor: fullname: Wilson, G. M. – volume: 81 start-page: 559 year: 2007 end-page: 575 ident: b14 publication-title: Am. J. Hum. Genet. contributor: fullname: Purcell, S. – volume: 60 start-page: 1187 year: 2003 end-page: 1192 ident: b1 publication-title: Arch. Gen. Psychiatry contributor: fullname: Neale, M. C. – volume: 14 start-page: 417 year: 1998 end-page: 422 ident: b16 publication-title: Trends Genet. contributor: fullname: Lupski, J. R. – volume: 40 start-page: 322 year: 2008 end-page: 328 ident: b17 publication-title: Nature Genet. contributor: fullname: Sharp, A. J. – volume: 68 start-page: 661 year: 2001 end-page: 673 ident: b26 publication-title: Am. J. Hum. Genet. contributor: fullname: Gurling, H. M. – volume: 13 start-page: 261 year: 2008 end-page: 266 ident: b5 publication-title: Mol. Psychiatry contributor: fullname: Friedman, J. I. – volume: 146 start-page: 854 year: 2008 end-page: 860 ident: b21 publication-title: Am. J. Med. Genet. A contributor: fullname: Bittel, D. C. – year: 2007 ident: b32 article-title: International Statistical Classification of Diseases and Related Health Problems – volume: 17 start-page: 482 year: 2007 end-page: 491 ident: b28 publication-title: Genome Res. contributor: fullname: Shaikh, T. H. – volume: 82 start-page: 477 year: 2008 end-page: 488 ident: b8 publication-title: Am. J. Hum. Genet. contributor: fullname: Marshall, C. R. – volume: 320 start-page: 539 year: 2008 end-page: 543 ident: b2 publication-title: Science contributor: fullname: Walsh, T. – volume: 19 start-page: 171 year: 1996 end-page: 176 ident: b18 publication-title: Trends Neurosci. contributor: fullname: Pearlson, G. D. – volume: 92 start-page: 7612 year: 1995 end-page: 7616 ident: b19 publication-title: Proc. Natl Acad. Sci. USA contributor: fullname: Karayiorgou, M. – volume: 131 start-page: 1235 year: 2007 end-page: 1247 ident: b29 publication-title: Cell contributor: fullname: Lupski, J. R. A. – ident: b15 publication-title: Nature Genet. contributor: fullname: Korn, J. – volume: 105 start-page: 669 year: 2001 end-page: 674 ident: b23 publication-title: Am. J. Med. Genet. contributor: fullname: Xu, J. – volume: 38 start-page: 1038 year: 2006 end-page: 1042 ident: b24 publication-title: Nature Genet. contributor: fullname: Sharp, A. J. – volume: 17 start-page: 458 year: 2008 end-page: 465 ident: b3 publication-title: Hum. Mol. Genet. contributor: fullname: Kirov, G. – volume: 94 start-page: 587 year: 1997 end-page: 592 ident: b22 publication-title: Proc. Natl Acad. Sci. USA contributor: fullname: Freedman, R. – volume: 344 start-page: 531 year: 2006 end-page: 539 ident: b7 publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Moon, H. J. – ident: b13 publication-title: Nature Genet. contributor: fullname: McCarroll, S. – volume: 52 start-page: 103 year: 2006 end-page: 121 ident: b11 publication-title: Neuron contributor: fullname: Lupski, J. R. – volume: 18 start-page: 74 year: 2002 end-page: 82 ident: b27 publication-title: Trends Genet. contributor: fullname: Lupski, J. R. – year: 2000 ident: b31 article-title: Diagnostic and Statistical Manual of Mental Disorders – volume: 9 start-page: 489 year: 2000 end-page: 501 ident: b20 publication-title: Hum. Mol. Genet. contributor: fullname: Shaikh, T. H. – ident: 10.1038/nature07229 b30 publication-title: Nature contributor: fullname: Stefansson, H. – volume: 141 start-page: 571 year: 2006 end-page: 575 ident: b4 publication-title: Am. J. Med. Genet. B. Neuropsychiatr. Genet. contributor: fullname: Flomen, R. H. – volume: 358 start-page: 667 year: 2008 end-page: 675 ident: b10 publication-title: N. Engl. J. Med. contributor: fullname: Weiss, L. A. – volume: 73 start-page: 1 year: 2006 end-page: 27 ident: b12 publication-title: Int. Rev. Neurobiol. contributor: fullname: Owen, M. J. – volume: 316 start-page: 445 year: 2007 end-page: 449 ident: CR9 article-title: Strong association of copy number mutations with autism publication-title: Science doi: 10.1126/science.1138659 contributor: fullname: Sebat – volume: 14 start-page: 417 year: 1998 end-page: 422 ident: CR16 article-title: Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits publication-title: Trends Genet. doi: 10.1016/S0168-9525(98)01555-8 contributor: fullname: Lupski – volume: 146 start-page: 854 year: 2008 end-page: 860 ident: CR21 article-title: Array comparative genomic hybridization (aCGH) analysis in Prader–Willi syndrome publication-title: Am. J. Med. Genet. A doi: 10.1002/ajmg.a.32249 contributor: fullname: Bittel – ident: CR30 – volume: 15 start-page: 743 year: 2006 end-page: 749 ident: CR6 article-title: DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddi489 contributor: fullname: Wilson – volume: 288 start-page: 678 year: 2000 end-page: 682 ident: CR25 article-title: Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21–q22 publication-title: Science doi: 10.1126/science.288.5466.678 contributor: fullname: Bassett – volume: 68 start-page: 661 year: 2001 end-page: 673 ident: CR26 article-title: Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21–22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3–24 and 20q12.1–11.23 publication-title: Am. J. Hum. Genet. doi: 10.1086/318788 contributor: fullname: Gurling – volume: 9 start-page: 489 year: 2000 end-page: 501 ident: CR20 article-title: Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: genomic organization and deletion endpoint analysis publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/9.4.489 contributor: fullname: Shaikh – volume: 73 start-page: 1 year: 2006 end-page: 27 ident: CR12 article-title: Chromosome 22 deletion syndrome and schizophrenia publication-title: Int. Rev. Neurobiol. doi: 10.1016/S0074-7742(06)73001-X contributor: fullname: Owen – volume: 131 start-page: 1235 year: 2007 end-page: 1247 ident: CR29 article-title: DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders publication-title: Cell doi: 10.1016/j.cell.2007.11.037 contributor: fullname: Lupski – volume: 52 start-page: 103 year: 2006 end-page: 121 ident: CR11 article-title: Genomic rearrangements and gene copy-number alterations as a cause of nervous system disorders publication-title: Neuron doi: 10.1016/j.neuron.2006.09.027 contributor: fullname: Lupski – volume: 81 start-page: 559 year: 2007 end-page: 575 ident: CR14 article-title: PLINK: a tool set for whole-genome association and population-based linkage analyses publication-title: Am. J. Hum. Genet. doi: 10.1086/519795 contributor: fullname: Purcell – volume: 38 start-page: 1038 year: 2006 end-page: 1042 ident: CR24 article-title: Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome publication-title: Nature Genet. doi: 10.1038/ng1862 contributor: fullname: Sharp – volume: 141 start-page: 571 year: 2006 end-page: 575 ident: CR4 article-title: Association study of CHRFAM7A copy number and 2 bp deletion polymorphisms with schizophrenia and bipolar affective disorder publication-title: Am. J. Med. Genet. B. Neuropsychiatr. Genet. doi: 10.1002/ajmg.b.30306 contributor: fullname: Flomen – volume: 60 start-page: 1187 year: 2003 end-page: 1192 ident: CR1 article-title: Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies publication-title: Arch. Gen. Psychiatry doi: 10.1001/archpsyc.60.12.1187 contributor: fullname: Neale – volume: 358 start-page: 667 year: 2008 end-page: 675 ident: CR10 article-title: Association between microdeletion and microduplication at 16p11.2 and autism publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa075974 contributor: fullname: Weiss – volume: 344 start-page: 531 year: 2006 end-page: 539 ident: CR7 article-title: Identification of DNA copy-number aberrations by array-comparative genomic hybridization in patients with schizophrenia publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2006.03.156 contributor: fullname: Moon – volume: 18 start-page: 74 year: 2002 end-page: 82 ident: CR27 article-title: Genome architecture, rearrangements and genomic disorders publication-title: Trends Genet. doi: 10.1016/S0168-9525(02)02592-1 contributor: fullname: Lupski – ident: CR15 – volume: 19 start-page: 171 year: 1996 end-page: 176 ident: CR18 article-title: Schizophrenia, the heteromodal association neocortex and development: potential for a neurogenetic approach publication-title: Trends Neurosci. doi: 10.1016/S0166-2236(96)10022-9 contributor: fullname: Pearlson – volume: 320 start-page: 539 year: 2008 end-page: 543 ident: CR2 article-title: Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia publication-title: Science doi: 10.1126/science.1155174 contributor: fullname: Walsh – ident: CR31 – ident: CR13 – volume: 40 start-page: 322 year: 2008 end-page: 328 ident: CR17 article-title: A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures publication-title: Nature Genet. doi: 10.1038/ng.93 contributor: fullname: Sharp – volume: 94 start-page: 587 year: 1997 end-page: 592 ident: CR22 article-title: Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.94.2.587 contributor: fullname: Freedman – volume: 82 start-page: 477 year: 2008 end-page: 488 ident: CR8 article-title: Structural variation of chromosomes in autism spectrum disorder publication-title: Am. J. Hum. Genet. doi: 10.1016/j.ajhg.2007.12.009 contributor: fullname: Marshall – ident: CR32 – volume: 92 start-page: 7612 year: 1995 end-page: 7616 ident: CR19 article-title: Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.92.17.7612 contributor: fullname: Karayiorgou – volume: 105 start-page: 669 year: 2001 end-page: 674 ident: CR23 article-title: Evidence for linkage disequilibrium between the α -nicotinic receptor gene ( ) locus and schizophrenia in Azorean families publication-title: Am. J. Med. Genet. doi: 10.1002/ajmg.1549 contributor: fullname: Xu – volume: 17 start-page: 458 year: 2008 end-page: 465 ident: CR3 article-title: Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddm323 contributor: fullname: Kirov – volume: 13 start-page: 261 year: 2008 end-page: 266 ident: CR5 article-title: CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy publication-title: Mol. Psychiatry doi: 10.1038/sj.mp.4002049 contributor: fullname: Friedman – volume: 17 start-page: 482 year: 2007 end-page: 491 ident: CR28 article-title: Low copy repeats mediate distal chromosome 22q11.2 deletions: sequence analysis predicts breakpoint mechanisms publication-title: Genome Res. doi: 10.1101/gr.5986507 contributor: fullname: Shaikh – volume: 40 start-page: 322 year: 2008 ident: BFnature07239_CR17 publication-title: Nature Genet. doi: 10.1038/ng.93 contributor: fullname: AJ Sharp – volume: 82 start-page: 477 year: 2008 ident: BFnature07239_CR8 publication-title: Am. J. Hum. Genet. doi: 10.1016/j.ajhg.2007.12.009 contributor: fullname: CR Marshall – volume: 14 start-page: 417 year: 1998 ident: BFnature07239_CR16 publication-title: Trends Genet. doi: 10.1016/S0168-9525(98)01555-8 contributor: fullname: JR Lupski – volume: 19 start-page: 171 year: 1996 ident: BFnature07239_CR18 publication-title: Trends Neurosci. doi: 10.1016/S0166-2236(96)10022-9 contributor: fullname: CA Ross – volume: 344 start-page: 531 year: 2006 ident: BFnature07239_CR7 publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2006.03.156 contributor: fullname: HJ Moon – volume: 288 start-page: 678 year: 2000 ident: BFnature07239_CR25 publication-title: Science doi: 10.1126/science.288.5466.678 contributor: fullname: LM Brzustowicz – volume: 105 start-page: 669 year: 2001 ident: BFnature07239_CR23 publication-title: Am. J. Med. Genet. doi: 10.1002/ajmg.1549 contributor: fullname: J Xu – volume: 38 start-page: 1038 year: 2006 ident: BFnature07239_CR24 publication-title: Nature Genet. doi: 10.1038/ng1862 contributor: fullname: AJ Sharp – ident: BFnature07239_CR31 – volume: 17 start-page: 458 year: 2008 ident: BFnature07239_CR3 publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddm323 contributor: fullname: G Kirov – ident: BFnature07239_CR30 doi: 10.1038/nature07229 – volume: 146 start-page: 854 year: 2008 ident: BFnature07239_CR21 publication-title: Am. J. Med. Genet. A doi: 10.1002/ajmg.a.32249 contributor: fullname: MG Butler – volume: 15 start-page: 743 year: 2006 ident: BFnature07239_CR6 publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddi489 contributor: fullname: GM Wilson – volume: 316 start-page: 445 year: 2007 ident: BFnature07239_CR9 publication-title: Science doi: 10.1126/science.1138659 contributor: fullname: J Sebat – volume: 94 start-page: 587 year: 1997 ident: BFnature07239_CR22 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.94.2.587 contributor: fullname: R Freedman – volume: 358 start-page: 667 year: 2008 ident: BFnature07239_CR10 publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa075974 contributor: fullname: LA Weiss – volume: 9 start-page: 489 year: 2000 ident: BFnature07239_CR20 publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/9.4.489 contributor: fullname: TH Shaikh – volume: 60 start-page: 1187 year: 2003 ident: BFnature07239_CR1 publication-title: Arch. Gen. Psychiatry doi: 10.1001/archpsyc.60.12.1187 contributor: fullname: PF Sullivan – volume: 68 start-page: 661 year: 2001 ident: BFnature07239_CR26 publication-title: Am. J. Hum. Genet. doi: 10.1086/318788 contributor: fullname: HM Gurling – volume: 18 start-page: 74 year: 2002 ident: BFnature07239_CR27 publication-title: Trends Genet. doi: 10.1016/S0168-9525(02)02592-1 contributor: fullname: P Stankiewicz – ident: BFnature07239_CR13 – ident: BFnature07239_CR32 – volume: 17 start-page: 482 year: 2007 ident: BFnature07239_CR28 publication-title: Genome Res. doi: 10.1101/gr.5986507 contributor: fullname: TH Shaikh – volume: 141 start-page: 571 year: 2006 ident: BFnature07239_CR4 publication-title: Am. J. Med. Genet. B. Neuropsychiatr. Genet. doi: 10.1002/ajmg.b.30306 contributor: fullname: RH Flomen – ident: BFnature07239_CR15 – volume: 81 start-page: 559 year: 2007 ident: BFnature07239_CR14 publication-title: Am. J. Hum. Genet. doi: 10.1086/519795 contributor: fullname: S Purcell – volume: 92 start-page: 7612 year: 1995 ident: BFnature07239_CR19 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.92.17.7612 contributor: fullname: M Karayiorgou – volume: 13 start-page: 261 year: 2008 ident: BFnature07239_CR5 publication-title: Mol. Psychiatry doi: 10.1038/sj.mp.4002049 contributor: fullname: JI Friedman – volume: 52 start-page: 103 year: 2006 ident: BFnature07239_CR11 publication-title: Neuron doi: 10.1016/j.neuron.2006.09.027 contributor: fullname: JA Lee – volume: 131 start-page: 1235 year: 2007 ident: BFnature07239_CR29 publication-title: Cell doi: 10.1016/j.cell.2007.11.037 contributor: fullname: JA Lee – volume: 73 start-page: 1 year: 2006 ident: BFnature07239_CR12 publication-title: Int. Rev. Neurobiol. doi: 10.1016/S0074-7742(06)73001-X contributor: fullname: NM Williams – volume: 320 start-page: 539 year: 2008 ident: BFnature07239_CR2 publication-title: Science doi: 10.1126/science.1155174 contributor: fullname: T Walsh |
| SSID | ssj0005174 ssj0014407 |
| Score | 2.575237 |
| Snippet | Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90% (ref. 1).... The genetics of schizophrenia The genetics of schizophrenia and other mental disorders are complex and poorly understood, and made even harder to study because... Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73-90%.... Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73 - 90% ( ref.... |
| SourceID | swepub pubmedcentral proquest gale crossref pubmed pascalfrancis springer nature |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 237 |
| SubjectTerms | Adult and adolescent clinical studies Biological and medical sciences Case-Control Studies Chromosome Deletion Chromosomes Chromosomes, Human - genetics Colleges & universities Gene Dosage - genetics Gene Duplication Genes Genetic aspects Genetic Predisposition to Disease - genetics Genetic variance Genetic variation Genome, Human - genetics Humanities and Social Sciences Humans Intellectual disabilities letter Medical sciences MEDICIN Medicin och hälsovetenskap MEDICINE Mental disorders Models, Genetic multidisciplinary Oligonucleotide Array Sequence Analysis Polymorphism, Single Nucleotide - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Risk factors Schizophrenia Schizophrenia - genetics Science Science (multidisciplinary) Sequence Deletion - genetics |
| Title | Rare chromosomal deletions and duplications increase risk of schizophrenia |
| URI | http://dx.doi.org/10.1038/nature07239 https://link.springer.com/article/10.1038/nature07239 https://www.ncbi.nlm.nih.gov/pubmed/18668038 https://www.proquest.com/docview/204527929 https://search.proquest.com/docview/20972045 https://search.proquest.com/docview/743424435 https://pubmed.ncbi.nlm.nih.gov/PMC3912847 https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109079 http://kipublications.ki.se/Default.aspx?queryparsed=id:117547471 |
| Volume | 455 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1bb9MwFLbYJiQkhNi4dYMSoY3LQ7Q6Fyd5Qm23MiZRobKxvlmO7XQVIuma5v9zTuKmzQg8tJXqL4mTc3LyxT7-DiHHQFJVAq5gA_fWtsdEYMfMCe1YeVQ4wlVROZjzbcwurr3LqT81uTm5Satcx8QyUKtM4hj5Kcqmo9hd9HlxZ2PRKJxcNRU0dsgedQKGGX3h6Msmw-OeCLNZntdzw9NKNbMXOFgkfOuBZMJyrar5eCFyuFZJVeSijYX-nUxZz6jeUx8tn1ijp-SJoZpWv_KNffJApwfkYZnyKfMDsm9u69z6aLSnPz0jlxOx1Ja8xSS9PPsNm2OhnNI3LZEqSxWb-W5rniLlzLWF-elWllj5dgbfc3I9Or8aXtim3IItI99b2VQnWJAKXok1vJR5vp-EWgFddFjANLA-KphwVOxKATwpCGIvhkcbA_6oqNJxQt0XZDfNUv2KWNKRTGmH6ki5ng49oah0VRwGksbAMaIOOV5fc76oVDV4ORvuhnzLNABDe3DUqUgxEWYmijzn_aub4Zj3KfQ0gpdgv0PetcG-_pg0QB8MKMnATlKY5QfQYVTAaiCPGki5mN_xrdb3jdZZZaG23RxWp1KfYePMug3PqjEO8CsIqQw6sXY1bqJKzut7oEPe1q0QDnCOR6Q6KxASYdkhOLr1DwRQRlzc6ALkZeW5GxOEjIVggw4JGj5dA1CLvNmSzm9LTXI3KolOh5ysvX_T7VbLnlS3RmPXZ_OffZ4tZ7woMDOiFwDOacEht-Dm_19z_PBco2y97-EYC5ioZaMaj1hg_eC4h_-9yEfk0To5iNLXZHe1LPQbYKCruEt2gmkA3-GQdsuY0yV7_cHZYAS_g_Px98kfJGuN1Q |
| link.rule.ids | 230,314,780,784,885,12056,12223,12765,21388,27924,27925,31719,31720,33266,33267,33373,33374,33744,33745,43310,43579,43600,43805,73745,74014,74035,74302 |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1bb9MwFLagE2ISQmxc1g22CG1cHqLVuTjJEypjUze2CpUO9mY5ttNViKRrmv_POYmbNiPw0Jf4S-r4nJx8jo-_Q8ghkFSVgCvYwL217TER2DFzQjtWHhWOcFVUfsy5GrLBtXdx49-Y3JzcpFUuY2IZqFUm8Rv5Mcqmo9hd9Gl2Z2PRKFxcNRU0HpINFE73O2Tj8-nw22iV43FPhtls0Ou54XGlm9kLHCwTvvZKMoG51tV8MhM5jFZSlblo46F_p1PWa6r39EfLd9bZM_LUkE2rX3nHFnmg023yqEz6lPk22TIPdm59MOrTH5-Ti5GYa0veYppenv2G07FUTumdlkiVpYrVirc1TZF05trCDHUrS6x8PYfvBbk-Ox2fDGxTcMGWke8tbKoTLEkFk2IN0zLP95NQKyCMDguYBt5HBROOil0pgCkFQezF8HJjwCAVVTpOqPuSdNIs1TvEko5kSjtUR8r1dOgJRaWr4jCQNAaWEXXJ4XLM-azS1eDlergb8jXTAAztwVGpIsVUmIko8pz3xz9PhrxPoacRTIP9LnnbBjv_PmqA3htQkoGdpDAbEKDDqIHVQO41kHI2veNrre8arZPKQm2X2a1upb7Dxp3tNzyrxjjAsCCoMujE0tW4iSs5r5-CLjmoWyEg4CqPSHVWICTCwkPw79Y_EEAacXujC5BXleeuTBAyFoINuiRo-HQNQDXyZks6vS1Vyd2opDpdcrT0_lW3Wy17VD0ajUt_mf7o82w-4UWBuRG9AHBOCw7ZBTfHf03xx3ONwvW-h19ZwEQtJ9V4xALvB8fd_e8gH5DHg_HVJb88H37dI5vLVCFKX5POYl7oN8BHF_G-iTp_APu4jWY |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1bb9MwFLagE2gSQmxc1g02C21cHqI2Nyd5QmVbtQ2oprLB3iwndroKkXR18_85J3HTZgQe-hJ_SZ2c4-PP8cl3CDkEkipTcAULuLeyPCYCK2ZOaMXSs4UjXBmVL3O-jdjZtXdx498YSSFt0iqXMbEM1DJP8B15D2XTUewu6qUmK-LyZPhpdmdhASncaDXVNB6SDZgU-06HbHw-HV2OV_ke9ySZzcd6fTfsVRqa_cDBkuFr05MJ0rXG5pOZ0PDk0qrkRRsn_Tu1st5fvadFWs5fw2fkqSGedFB5yhZ5oLJt8qhMAE30Ntkyg1zTD0aJ-uNzcjEWc0WTW0zZ0_lvOB3L5pSeSkUmqSxWu990miEB1YpitjrNU6rX8_lekOvh6dXxmWWKL1hJ5HsLy1YplqeCBbKCJZrn-2moJJBHhwVMAQe0BROOjN1EAGsKgtiLYaJjwCalLVWc2u5L0snyTO0QmjgJk8qxVSRdT4WekHbiyjgMEjsGxhF1yeHymfNZpbHBy71xN-RrpgEY2oOjakWGDjARhdZ8cPXzeMQHNvQ0giWx3yVv22Dn38cN0HsDSnOwUyLMxwjQYdTDaiD3GshkNr3ja63vGq2TykJtl9mtbqW-w8ad7Tc8q8Y4wLYgwDLoxNLVuIkxmtcjoksO6lYIDrjjIzKVFwiJsAgR_Dv9BwLGCn7q6ALkVeW5KxOEjIVggy4JGj5dA1CZvNmSTW9LhXI3KmlPlxwtvX_V7VbLHlVDo3Hpk-mPAc_nE14UmCfRDwDntOCQaXBz_NcUf1wrFLH3PXzjAiZqOanGIxbWAOC4u_99yAfkMQQc_vV89GWPbC6zhmz7Neks5oV6A9R0Ee-boPMHoniRkw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Rare+chromosomal+deletions+and+duplications+increase+risk+of+schizophrenia&rft.jtitle=Nature+%28London%29&rft.date=2008-09-11&rft.issn=0028-0836&rft.eissn=1476-4687&rft.volume=455&rft.issue=7210&rft.spage=237&rft.epage=241&rft_id=info:doi/10.1038%2Fnature07239&rft.externalDocID=nature07239 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0028-0836&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0028-0836&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0028-0836&client=summon |