High Dimensional Clustering and Identification of Immune Cell Hybrid Populations in B-ALL across the Disease Continuum

• Published in: Blood Vol. 142; no. Supplement 1; p. 5627
• Main Authors: Newman, Matthew, De Sa, Hong, Byrd, Kaelan, Patel, Ranish, Parappilly, Michael S., Kosaka, Yoko, Lind, Evan F., Leonard, Jessica T.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 02.11.2023

Introduction: Nearly half of adults with acute lymphoblastic leukemia (ALL) will experience relapse of their disease, and those with relapsed ALL carry a worse prognosis than those who remain in remission. The influence of the tumor immune microenvironment (TME) on relapse and survival outcomes in A...