Abstract 3015: Matrix Metalloproteinase Inhibition In Rat Abdominal Aortic Aneurysm

• Published in: Arteriosclerosis, thrombosis, and vascular biology Vol. 44; no. Suppl_1; p. A3015
• Main Authors: Zaghloul, Mohamed, Elizondo-Benedetto, Santiago, Arif, Batool, Heo, Gyu Seong, Luehmann, Hannah, Liu, Yongjian, Gropler, Robert J, Sadeghi, Mehran M, Zayed, Mohamed A
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.05.2024
• Subjects: Targeted therapeutics; Inflammation; Abdominal aortic aneurysm

Background: Matrix metalloproteinases (MMPs) have a robust proteolytic activity and play a fundamental role in degradation of extracellular matrix proteins. This degradation is a hallmark of the initiation, progression, and rupture of abdominal aortic aneurysms (AAAs). Hypothesis: We hypothesized th...