Impact of Mutational Landscape and Biomarkers on Response of Luspatercept (ACE-536) Treatment of Anemia in Non-Transfusion Dependent IPSS-R Lower Risk MDS Japanese Subjects (ACE-536-MDS-003- a Ph2 single-arm study)

• Published in: Blood Vol. 144; no. Supplement 1; p. 6725
• Main Authors: Jaiswal, Bijay Shankar, Ugidos, Manuel, Kosugi, Hiroshi, Matsue, Kosei, Murakami, Hiromi, Hayakawa, Jin, Lopes de Menezes, Daniel, Gandhi, Anita K., Suragani, Rajasekhar N.V.S.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 05.11.2024

Background: Myelodysplastic syndromes (MDS) are among the most common hematologic malignancies affecting older adults characterized by ineffective hematopoiesis and typically manifest as anemia, cytopenia, an increased risk of infection and hemorrhage and often leading to acute myeloid leukemia (AML...