Epor Stimulates Rapid Cycling and Larger Red Cells during Mouse and Human Erythropoiesis

• Published in: Blood Vol. 138; no. Supplement 1; p. 852
• Main Authors: Hidalgo, Daniel, Bejder, Jacob, Pop, Ramona, Gellatly, Kyle, Hwang, Yung, Scalf, S. Maxwell, Eastman, Anna, Chen, Jane-Jane, Zhu, Lihua Julie, Heuberger, Jules, Guo, Shangqin, Koury, Mark J., Nordsborg, Nikolai Baastrup, Socolovsky, Merav
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 23.11.2021

Erythroid terminal differentiation (ETD) entails cell divisions coupled to decreasing cell size. The tight link between the number of cell divisions and red cell size is apparent in nutritional deficiencies or genetic variants in which fewer cycles result in larger red cells. Here we investigated no...