Predicting Antigen-Specific T Cell Immunity Against Wilms Tumor 1 in Hematologic Cancer

• Published in: Blood Vol. 144; no. Supplement 1; p. 3596
• Main Authors: Jokinen, Emmi, Ford, Brittany, Huuhtanen, Jani, Forstén, Sofia, Klievink, Jay, Antignani, Gabriella, Brück, Oscar E., Cerullo, Vincenzo, Peltonen, Karita, Mustjoki, Satu
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 05.11.2024

Wilms tumor 1 (WT1) is a tumor-associated antigen expressed in both solid tumors and hematological cancers. In myeloid malignancies, such as acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and myelodysplastic syndrome (MDS), WT1 is overexpressed and relates to worse prognosis. Clinical...