Homozygosity for -2518 G Allele Variant of MCP-1 Predisposes to Adverse Presentation and Outcome in Primary Myelofibrosis

• Published in: Blood Vol. 134; no. Supplement_1; p. 1689
• Main Authors: Masselli, Elena, Carubbi, Cecilia, Pozzi, Giulia, Percesepe, Antonio, Campanelli, Rita, Villani, Laura, Gobbi, Giuliana, Rosti, Vittorio, Massa, Margherita, Barosi, Giovanni, Vitale, Marco
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 13.11.2019

Primary myelofibrosis (PMF) is the most aggressive Philadelphia-negative myeloproliferative neoplasm. Heterogeneity in disease phenotype and outcome led to investigate the influence of germline host genetic variations on disease onset and evolution. We recently found that patients with secondary mye...