Abstract 1927: High-throughput cell line panel drug screening in organoids and 3D systems

• Published in: Cancer research (Chicago, Ill.) Vol. 79; no. 13_Supplement; p. 1927
• Main Authors: Scales, Tim M., Rada-Kovacs, Anett, Pemberton, Helen N., Wiggins, Ceri M., McCarthy, Nicola J., Little, Annette S., Sorrell, David A.
• Format: Journal Article
• Language: English
• Published: 01.07.2019

Abstract Cell panel screening of cancer lines grown in standard 2D conditions is a well-established component of the drug discovery toolbox. A sufficiently large cell line panel, reflecting the molecular heterogeneity within a cancer type/sub-type, is required to detect correlations with robust stat...