A borderline range for Quantiferon Gold In-Tube results

• Published in: PloS one Vol. 12; no. 11; p. e0187313
• Main Authors: Jonsson, Jerker, Westman, Anna, Bruchfeld, Judith, Sturegård, Erik, Gaines, Hans, Schön, Thomas
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 02.11.2017; Public Library of Science (PLoS)
• Subjects: Biology and Life Sciences; Clinical Medicine; Critical care; Gold; Health care; Hospitals; Humans; Infections; Infectious diseases; Infectious Medicine; Infektionsmedicin; Interferon; Interferon gamma; Interferon-gamma - blood; Klinisk medicin; Laboratories; Latent Tuberculosis - diagnosis; Medical and Health Sciences; Medical diagnosis; Medical personnel; Medicin och hälsovetenskap; Medicine; Medicine and Health Sciences; Mycobacterium tuberculosis; People and places; Public health; Reference Values; Reproducibility of Results; Research and Analysis Methods; Social Sciences; Sweden; Tuberculosis; Sweden

Interferon gamma release assays like Quantiferon Gold In-Tube (QFT) are used to identify individuals infected with Mycobacterium tuberculosis. A dichotomous cut-off (0.35 IU/ml) defines a positive QFT without considering test variability. Our objective was to evaluate the introduction of a borderlin...