Abstract 11533: Genetic Prediction Tool Using LPA Haplotypes Improves Identification of Patients with Elevated Lipoprotein(a)

• Published in: Circulation (New York, N.Y.) Vol. 144; no. Suppl_1; p. A11533
• Main Authors: Atri, Deepak, Mukamel, Ronen E, Loh, Po-ru, Blankstein, Ron, Gupta, Rajat M
• Format: Journal Article
• Language: English
• Published: Lippincott Williams & Wilkins 16.11.2021

IntroductionMultiple lines of evidence support the causal role of serum lipoprotein (a) [Lp(a)] in the pathogenesis of cardiovascular disease, including CAD/MI and ischemic stroke. Mendelian randomization studies demonstrate that genetic variation is the principal determinant of serum Lp(a) level, a...