Abstract 9526: Fto Demethylase Mediates Altered N6-methyladenosine (m6a)-rna Modification in Human Failing Heart and Stressed-Induced Rat Cardiomyocytes

• Published in: Circulation (New York, N.Y.) Vol. 144; no. Suppl_1; p. A9526
• Main Authors: Dubey, Praveen K, Dubey, Shubham, Patil, Mallikarjun, Singh, Sarojini, Ahuja, Paras, pogwizd, Steven, Krishnamurthy, Prasanna
• Format: Journal Article
• Language: English
• Published: Lippincott Williams & Wilkins 16.11.2021

BackgroundN6-methyladenosine (m6A) methylation is one of the important posttranscriptional modification of RNA, which affects RNA splicing, translation and stability. These modifications are dynamically regulated by writers, readers and erasers, and their alteration affects m6A modification and have...