Genome-wide association study identifies three new melanoma susceptibility loci

• Published in: Nature genetics Vol. 43; no. 11; pp. 1108 - 1113
• Main Authors: Barrett, Jennifer H, Iles, Mark M, Harland, Mark, Taylor, John C, Aitken, Joanne F, Andresen, Per Arne, Akslen, Lars A, Armstrong, Bruce K, Avril, Marie-Francoise, Azizi, Esther, Bakker, Bert, Bergman, Wilma, Bianchi-Scarrà, Giovanna, Bressac-de Paillerets, Brigitte, Calista, Donato, Cannon-Albright, Lisa A, Corda, Eve, Cust, Anne E, Dębniak, Tadeusz, Duffy, David, Dunning, Alison M, Easton, Douglas F, Friedman, Eitan, Galan, Pilar, Ghiorzo, Paola, Giles, Graham G, Hansson, Johan, Hocevar, Marko, Höiom, Veronica, Hopper, John L, Ingvar, Christian, Janssen, Bart, Jenkins, Mark A, Jönsson, Göran, Kefford, Richard F, Landi, Giorgio, Landi, Maria Teresa, Lang, Julie, Lubiński, Jan, Mackie, Rona, Malvehy, Josep, Martin, Nicholas G, Molven, Anders, Montgomery, Grant W, van Nieuwpoort, Frans A, Novakovic, Srdjan, Olsson, Håkan, Pastorino, Lorenza, Puig, Susana, Puig-Butille, Joan Anton, Randerson-Moor, Juliette, Snowden, Helen, Tuominen, Rainer, Van Belle, Patricia, van der Stoep, Nienke, Whiteman, David C, Zelenika, Diana, Han, Jiali, Fang, Shenying, Lee, Jeffrey E, Wei, Qingyi, Lathrop, G Mark, Gillanders, Elizabeth M, Brown, Kevin M, Goldstein, Alisa M, Kanetsky, Peter A, Mann, Graham J, MacGregor, Stuart, Elder, David E, Amos, Christopher I, Hayward, Nicholas K, Gruis, Nelleke A, Demenais, Florence, Bishop, Julia A Newton, Bishop, D Timothy
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.11.2011; Nature Publishing Group
• Subjects: 631/208/205/2138; 631/208/727/2000; 692/699/67/1813/1634; Agriculture; Analysis; Animal Genetics and Genomics; Awards & honors; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Cancer; Cancer and Oncology; Cancer och onkologi; Cancer Research; Case-Control Studies; Chromosomes; Clinical Medicine; Càncer de pell; Dermatology; Disease susceptibility; Family medical history; Fundamental and applied biological sciences. Psychology; Gene Function; Genealogy; Genes; Genetic aspects; Genetic Predisposition to Disease; Genetic research; Genetics of eukaryotes. Biological and molecular evolution; Genome-Wide Association Study; Genomes; Genomics; Genètica mèdica; Human Genetics; Humans; Kirurgi; Klinisk medicin; letter; Life Sciences; Medical and Health Sciences; Medical genetics; Medical research; Medical sciences; Medicin och hälsovetenskap; Melanoma; Melanoma - genetics; Pigmentation; Polymorphism, Single Nucleotide; Single nucleotide polymorphisms; Skin cancer; Skin Neoplasms - genetics; Statistical analysis; Studies; Surgery; Tumors of the skin and soft tissue. Premalignant lesions; Identification; Malignant tumor; Locus; Malignant melanoma; Cancer; WOMEN; CUTANEOUS MALIGNANT-MELANOMA; POPULATION; METAANALYSIS; GENE; PHENOTYPIC CHARACTERISTICS; RISK; SEQUENCE VARIANTS; CANCER; NEVI

Timothy Bishop and colleagues of the GenoMEL Consortium report a genome-wide association study for melanoma, identifying three new susceptibility loci. We report a genome-wide association study for melanoma that was conducted by the GenoMEL Consortium. Our discovery phase included 2,981 individuals...