Effect of Animal and Industrial Trans Fatty Acids on HDL and LDL Cholesterol Levels in Humans - A Quantitative Review

• Published in: PloS one Vol. 5; no. 3; p. e9434
• Main Authors: Brouwer, I.A, Wanders, A.J, Katan, M.B
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 02.03.2010; Public Library of Science (PLoS)
• Subjects: Animals; biohydrogenation; blood; Blood cholesterol; Cardiovascular disease; Cardiovascular diseases; Chemical properties; Cholesterol; Cholesterol, HDL - metabolism; Cholesterol, LDL - metabolism; Comparative analysis; conjugated linoleic acid; Coronary artery disease; coronary disease; Coronary Disease - metabolism; Coronary heart disease; cows; Diet; energy; Fatty acids; Feeds; Health risks; healthy-human subjects; Heart; Heart diseases; High density lipoprotein; high density lipoprotein cholesterol; Humans; hydrogenated soybean oil; Hydrogenation; insulin sensitivity; linear models; Linoleic acid; Linoleic Acids, Conjugated - metabolism; Lipoproteins; Lipoproteins (high density); Lipoproteins (low density); Lipoproteins - blood; Lists; Low density lipoprotein; low density lipoprotein cholesterol; Low density lipoproteins; middle-aged men; moderately hyperlipidemic subjects; Monounsaturated fatty acids; Nutrition; plasma-lipids; Public Health and Epidemiology; Public Health and Epidemiology/Social and Behavioral Determinants of Health; Randomized Controlled Trials as Topic; Regression Analysis; Reviews; Risk; Rumen; serum-lipoproteins; Sheep; Trans fatty acids; Trans Fatty Acids - metabolism; Vegetable oils; United States > US; Netherlands

Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower HDL cholesterol, raise LDL cholesterol, and increase the risk of coronary heart disease. The effects of conjugated linoleic acid and trans fatt...