Consensus Virtual Screening of Dark Chemical Matter and Food Chemicals Uncover Potential Inhibitors of SARS-CoV-2 Main Protease

• Published in: ChemRxiv
• Main Authors: Santibáñez-Morán, Marisa G., López-López, Edgar, Prieto-Martínez, Fernando D., Sánchez-Cruz, Norberto, Medina-Franco, Jose L.
• Format: Paper
• Language: English
• Edition: 1
• Subjects: Chemical Biology; Chemistry; Chemoinformatics - Computational Chemistry; Computational Chemistry and Modeling; Drug Discovery and Drug Delivery Systems; COVID-19; data fusion; Dark Chemical Matter; SARS-CoV-2; drug discovery; virtual screening; coronavirus; Docking Studies; ChemoInformatics; food chemicals; similarity searching; foodinformatics

The COVID-19 pandemic caused by SARS-CoV-2 has claimed more than 380,000 lives Worldwide and more than 6.5 million people are infected. Unfortunately, there is no drug or vaccine for the treatment of COVID-19. The increasing information available of key molecular targets of SARS-CoV-2 and active com...