Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage - Komor, Alexis C.; Kim, Yongjoo B.; Packer, Michael S.; Zuris, John A.; Liu, David R. (Nature (London), 2016)
Keywords: 45/23; 45/41; 45/70; 631/1647/1511; 631/337/1427; 631/61/201/2110; 631/92/612/1229; Amino acids; Animals; APOBEC-1 Deaminase; Apolipoprotein E4 - genetics; Base Sequence; Cell Line; Clustered Regularly Interspaced Short Palindromic Repeats - genetics; CRISPR-Associated Proteins - metabolism; CRISPR-Cas Systems; Cytidine - genetics; Cytidine Deaminase - metabolism; Deoxyribonuclease I - metabolism; Deoxyribonucleic acid; DNA; DNA - genetics; DNA - metabolism; DNA Cleavage; DNA Repair; Enzymes; Gene targeting; Genes, p53 - genetics; Genetic disorders; Genetic engineering; Genetic Engineering - methods; Genetic research; Genome - genetics; Genomes; Genomics; Humanities and Social Sciences; Humans; INDEL Mutation - genetics; letter; Methods; Mice; multidisciplinary; Mutation; Point Mutation - genetics; Proteins; RNA, Guide, CRISPR-Cas Systems - genetics; Science; Structure; Templates, Genetic; Uracil-DNA Glycosidase - antagonists & inhibitors; Uridine - genetics; United States