P5005Diagnostic and prognostic utilities of insulin-like growth factor-binding protein-7 in patients presenting to the emergency department with dyspnea: results from the ICON-RELOADED study

• Published in: European heart journal Vol. 40; no. Supplement_1
• Main Authors: Ibrahim, N, Chen-Tournoux, A, Christenson, R H, Gaggin, H K, Hollander, J E, Levy, P D, Mang, A, Masson, S, Nagurney, J T, Nowak, R, Pang, P S, Peacock, W F, Rolny, V, Walters, E L, Januzzi, J L
• Format: Journal Article
• Language: English
• Published: Oxford University Press 01.10.2019
• Subjects: Acute Heart Failure: Biomarkers

Abstract Background Increased activity of insulin-like growth factor–binding protein-7 (IGFBP7) is associated with cellular senescence, tissue aging, and obesity. Prior studies in chronic heart failure (HF) have linked IGFBP7 to impaired myocardial relaxation. The role of IGFBP7 measurement in acute...