Sevoflurane and the Neonatal Brain: A Statistical Meta-Analysis of Potential Impacts

• Published in: Journal of neonatal surgery Vol. 14; no. 25S; pp. 471 - 483
• Main Authors: O. Ababneh, Muawieh, A. Shehab, Refaat, J. Alkayed, Omair, Khatib, Wael, Al-Nabulsi, Mozon Muhib Samih, Al-Buti, Firas G., T. Alsaad, Abdul Rahman
• Format: Journal Article
• Language: English
• Published: 19.05.2025

We performed a systematic meta-analysis to determine the neurodevelopmental effects of sevoflurane anesthesia in neonates. Although sevoflurane has favorable pharmacokinetics, making it a mainstay in neonatal anesthesia, preclinical studies suggest sevoflurane may have potential neurotoxicity during...