Adverse effect profile with low-dose methotrexate therapy in patients suffering with rheumatic diseases

• Published in: National journal of physiology, pharmacy and pharmacology Vol. 14; no. 5; pp. 1 - 830
• Main Authors: Parimi, Vijaya, Mirza, Mehdi, Bandaru, Rajiv, Surapareddy, Bhavana, Bala, Sudha, Rakesh, Srigaari
• Format: Journal Article
• Language: English
• Published: Surat Association of Physiologists, Pharmacists & Pharmacologists 01.01.2024
• Subjects: Acids; Bone marrow; Cancer therapies; Drug dosages; Hair loss; Immunology; Medical records; Nausea; Patients; Psoriasis; Rheumatic diseases; Rheumatoid arthritis; Rheumatology; Systematic review; Toxicity; Vitamin B; India

Background: Methotrexate (MTX) is the anchor drug for the management of many systemic inflammatory diseases. High-dose MTX is associated with various toxicities which may lead to drug discontinuation or interruption of therapy. Low-dose MTX is widely used for treating various systemic autoimmune dis...