Nucleophilic 18 F‐Labeling of Spirocyclic Iodonium Ylide or Boronic Pinacol Ester Precursors: Advantages and Disadvantages

• Published in: European journal of organic chemistry Vol. 2017; no. 3; pp. 453 - 458
• Main Authors: Petersen, Ida Nymann, Kristensen, Jesper Langgaard, Herth, Matthias Manfred
• Format: Journal Article
• Language: English
• Published: 18.01.2017

The field of labeling electron‐rich aryl compounds with nucleophilic [ 18 F]fluoride has recently expanded with radiofluorination strategies that apply boronic esters or spirocyclic iodonium ylides as precursors. Herein, we present a direct comparison of these strategies by using nine chemically div...