Ligand regulation of green fluorescent protein‐tagged forms of the human β 1 ‐ and β 2 ‐adrenoceptors; comparisons with the unmodified receptors

• Published in: British journal of pharmacology Vol. 130; no. 8; pp. 1825 - 1832
• Main Authors: McLean, Alison J, Milligan, Graeme
• Format: Journal Article
• Language: English
• Published: 29.01.2009

Stable clones of HEK293 cells expressing either FLAG TM epitope‐tagged, wild type human β 1 ‐ and β 2 ‐adrenoceptors or C‐terminally green fluorescent protein (GFP)‐tagged forms of these receptors were established. The binding affinity of [ 3 H]‐dihydroalprenolol and other ligands was little affecte...