Neurocritical Care Nutrition: Unique Considerations and Strategies for Optimizing Energy Supply and Metabolic Support in Critically Ill Patients
Neuro-critically ill patients face unique challenges in nutritional support due to varying metabolic and energy demands arising from clinical situations such as elevated intracranial pressure, trauma, stroke, epilepsy, targeted temperature management (TTM), and pharmacological interventions. Despite...
Saved in:
Published in | Journal of Neurointensive Care Vol. 6; no. 2; pp. 84 - 97 |
---|---|
Main Authors | , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
31.10.2023
|
Online Access | Get full text |
Cover
Loading…
Abstract | Neuro-critically ill patients face unique challenges in nutritional support due to varying metabolic and energy demands arising from clinical situations such as elevated intracranial pressure, trauma, stroke, epilepsy, targeted temperature management (TTM), and pharmacological interventions. Despite these challenges, there is a lack of systematic reviews addressing their specific needs. This study conducts a systematic review and narrative synthesis of the existing literature on nutritional support for neuro-critical patients, focusing on amino acids that act as neurotransmitters or their precursors. We examined nutritional requirements and timing in patients with stroke and traumatic brain injury, as well as energy and metabolic demands during TTM, a common therapeutic intervention in neuro-critical care. Our review aims to clarify uncertainties surrounding amino acid provision in neuro-critical patients and provide up-to-date recommendations on nutritional support for those with elevated intracranial pressure and undergoing TTM, serving as a foundation for future research and evidence-based guideline development. Key findings include the potential benefits of branched-chain amino acids (BCAAs) in neuro-critical care, the roles of methionine and serine, the significance of arginine in vascular constriction, the controversial role of glutamate in nutrition, and the potential benefits of selenium supplementation. We also discussed special considerations in nutritional support for neuro-critical patients, such as changes in energy demand, the influence of sedation on energy demand, and metabolism changes during TTM. Our review highlights the need for a better understanding of the unique metabolic requirements of neuro-critical patients and the development of evidence-based guidelines for optimal nutritional support in this population. |
---|---|
AbstractList | Neuro-critically ill patients face unique challenges in nutritional support due to varying metabolic and energy demands arising from clinical situations such as elevated intracranial pressure, trauma, stroke, epilepsy, targeted temperature management (TTM), and pharmacological interventions. Despite these challenges, there is a lack of systematic reviews addressing their specific needs. This study conducts a systematic review and narrative synthesis of the existing literature on nutritional support for neuro-critical patients, focusing on amino acids that act as neurotransmitters or their precursors. We examined nutritional requirements and timing in patients with stroke and traumatic brain injury, as well as energy and metabolic demands during TTM, a common therapeutic intervention in neuro-critical care. Our review aims to clarify uncertainties surrounding amino acid provision in neuro-critical patients and provide up-to-date recommendations on nutritional support for those with elevated intracranial pressure and undergoing TTM, serving as a foundation for future research and evidence-based guideline development. Key findings include the potential benefits of branched-chain amino acids (BCAAs) in neuro-critical care, the roles of methionine and serine, the significance of arginine in vascular constriction, the controversial role of glutamate in nutrition, and the potential benefits of selenium supplementation. We also discussed special considerations in nutritional support for neuro-critical patients, such as changes in energy demand, the influence of sedation on energy demand, and metabolism changes during TTM. Our review highlights the need for a better understanding of the unique metabolic requirements of neuro-critical patients and the development of evidence-based guidelines for optimal nutritional support in this population. |
Author | Kim, Jae Hyun Ha, Eun Jin Park, So Hee Shim, Youngbo Kim, Hyeseon Kim, Seung Bin Jung, Han-Gil Lee, Seungjoo Jung, Hee-Won Choo, Yoon Hee Kim, Moinay OH, JIWOONG Kim, Junhyung Jeon, Hanwool Kim, Jung Ook |
Author_xml | – sequence: 1 givenname: Jae Hyun surname: Kim fullname: Kim, Jae Hyun – sequence: 2 givenname: Yoon Hee surname: Choo fullname: Choo, Yoon Hee – sequence: 3 givenname: Moinay surname: Kim fullname: Kim, Moinay – sequence: 4 givenname: Hanwool surname: Jeon fullname: Jeon, Hanwool – sequence: 5 givenname: Hee-Won surname: Jung fullname: Jung, Hee-Won – sequence: 6 givenname: Eun Jin surname: Ha fullname: Ha, Eun Jin – sequence: 7 givenname: JIWOONG surname: OH fullname: OH, JIWOONG – sequence: 8 givenname: Youngbo surname: Shim fullname: Shim, Youngbo – sequence: 9 givenname: Seung Bin surname: Kim fullname: Kim, Seung Bin – sequence: 10 givenname: Han-Gil surname: Jung fullname: Jung, Han-Gil – sequence: 11 givenname: So Hee surname: Park fullname: Park, So Hee – sequence: 12 givenname: Jung Ook surname: Kim fullname: Kim, Jung Ook – sequence: 13 givenname: Junhyung surname: Kim fullname: Kim, Junhyung – sequence: 14 givenname: Hyeseon surname: Kim fullname: Kim, Hyeseon – sequence: 15 givenname: Seungjoo surname: Lee fullname: Lee, Seungjoo |
BookMark | eNpNkE1OwzAUhC1UJErpnqUvkOLEduKwQ1GBSqVFallH_q2MUjvYyaKcgiPThC5YvZnRaJ703YKJ804DcJ-iBc4oKx4-nZWLDGV4gVDOyiswzXJME5oxNPmnb8A8RisQIQWhaUmn4Gej--BlsJ2VvIEVDxpu-m7w3j3CD2e_eg0r76JVOvAhjZA7BXfd2emD1REaH-C27ezRflt3gEunw-EEd33bNqex-6Y7Lnxj5Rj60EHrYHX5ee6smga-n7e16-IduDa8iXp-uTOwf17uq9dkvX1ZVU_rRDJcJqIsZE5LYhQ3SNCiUAylChfaKGmYEgwbkTOiFJPKGJKatDQqI4QxjJQUGs8A-puVwccYtKnbYI88nOoU1SPTemBaD0zrkSn-Be4kcYM |
Cites_doi | 10.3389/fnsys.2016.00036 10.1007/s00134-016-4665-0 10.1016/j.plipres.2014.06.002 10.3389/fnins.2021.666601 10.1007/s00134-003-1988-4 10.1016/j.wneu.2019.08.119 10.1016/j.jocn.2006.03.013 10.1016/j.cmet.2022.01.005 10.1007/bf01402895 10.1378/chest.101.6.1619 10.1002/jnr.20744 10.1016/j.resuscitation.2014.08.018 10.1016/j.injury.2017.07.005 10.1002/jnr.21444 10.1177/0884533613498775 10.1177/0884533608326060 10.1016/j.neuropharm.2018.09.040 10.1093/ajcn/72.2.573s 10.3171/jns.2004.100.2.0266 10.1126/scitranslmed.3007092 10.18858/smn.2018.9.1.5 10.1177/0148607116655448 10.1177/014860710603000271 10.1007/bf00335165 10.1097/01.ccm.0000054868.93459.e1 10.1097/01.wcb.0000066287.21705.21 10.3390/nu14020342 10.1017/s1740925x11000093 10.1016/j.clnu.2008.06.006 10.1016/s0305-0491(96)00259-3 10.1177/0884533611434116 10.1007/s00702-014-1180-8 10.1111/j.1600-0404.1986.tb03254.x 10.1111/j.1471-4159.2004.02179.x 10.1016/j.clnu.2006.01.021 10.1073/pnas.0910280107 10.1097/00003246-199803000-00033 10.1164/ajrccm.153.3.8630539 10.1186/cc13962 10.1016/j.clnu.2021.05.012 10.1016/j.apmr.2005.03.022 10.1093/jn/136.1.207s 10.1016/j.jcrc.2013.08.017 10.3390/cancers11111628 10.3390/nu12040910 10.1227/00006123-198409000-00003 10.2174/1871527317666180627120501 10.1111/apa.12838 10.1016/j.resuscitation.2019.01.007 10.1016/j.neuint.2007.04.026 10.1016/j.resuscitation.2014.12.025 10.1016/j.jinorgbio.2015.09.003 10.1016/s0003-9993(00)90137-0 10.1002/jpen.1596 10.1002/jpen.2035 10.1159/000310330 10.1089/neu.2012.2491 10.1179/016164106x152052 10.1080/02699050500487571 10.3389/fneur.2015.00073 10.1136/jnnp.2004.042838 10.1080/03009734.2019.1659888 10.3390/pharmacy9030121 |
ContentType | Journal Article |
DBID | AAYXX CITATION |
DOI | 10.32587/jnic.2023.00689 |
DatabaseName | CrossRef |
DatabaseTitle | CrossRef |
DatabaseTitleList | CrossRef |
DeliveryMethod | fulltext_linktorsrc |
EISSN | 2635-5280 |
EndPage | 97 |
ExternalDocumentID | 10_32587_jnic_2023_00689 |
GroupedDBID | AAYXX CITATION M~E |
ID | FETCH-LOGICAL-c839-b97c6594fdaf0b577d801d37efdcf8db83fb684dd8cdff41f19fd2448830dcbe3 |
ISSN | 2635-5280 |
IngestDate | Thu Nov 21 20:49:37 EST 2024 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Issue | 2 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c839-b97c6594fdaf0b577d801d37efdcf8db83fb684dd8cdff41f19fd2448830dcbe3 |
OpenAccessLink | http://www.e-jnic.org/upload/pdf/jnic-2023-00689.pdf |
PageCount | 14 |
ParticipantIDs | crossref_primary_10_32587_jnic_2023_00689 |
PublicationCentury | 2000 |
PublicationDate | 2023-10-31 |
PublicationDateYYYYMMDD | 2023-10-31 |
PublicationDate_xml | – month: 10 year: 2023 text: 2023-10-31 day: 31 |
PublicationDecade | 2020 |
PublicationTitle | Journal of Neurointensive Care |
PublicationYear | 2023 |
References | ref13 ref57 ref12 ref56 ref15 ref59 ref14 ref58 ref53 ref52 ref11 ref55 ref10 ref54 ref17 ref16 ref19 ref18 ref51 ref50 ref46 ref45 ref48 ref47 ref42 ref41 ref44 ref43 ref49 ref7 Pardridge (ref8) 1986 ref9 ref4 ref3 ref6 ref5 ref40 ref35 ref34 ref37 ref36 Ozüm (ref21) 2007 ref30 ref32 ref2 ref1 ref39 ref38 Vanek (ref31) 2011 ref24 ref23 ref67 ref26 ref25 ref20 ref64 ref63 ref22 ref66 ref65 Kempski (ref33) 1990 ref28 ref27 ref29 ref60 ref62 ref61 |
References_xml | – ident: ref11 doi: 10.3389/fnsys.2016.00036 – ident: ref62 doi: 10.1007/s00134-016-4665-0 – ident: ref13 doi: 10.1016/j.plipres.2014.06.002 – ident: ref37 doi: 10.3389/fnins.2021.666601 – ident: ref59 doi: 10.1007/s00134-003-1988-4 – ident: ref19 doi: 10.1016/j.wneu.2019.08.119 – ident: ref20 doi: 10.1016/j.jocn.2006.03.013 – ident: ref38 doi: 10.1016/j.cmet.2022.01.005 – ident: ref44 doi: 10.1007/bf01402895 – ident: ref55 doi: 10.1378/chest.101.6.1619 – ident: ref14 doi: 10.1002/jnr.20744 – ident: ref63 doi: 10.1016/j.resuscitation.2014.08.018 – ident: ref39 doi: 10.1016/j.injury.2017.07.005 – ident: ref26 doi: 10.1002/jnr.21444 – ident: ref45 doi: 10.1177/0884533613498775 – ident: ref49 doi: 10.1177/0884533608326060 – ident: ref28 doi: 10.1016/j.neuropharm.2018.09.040 – ident: ref7 doi: 10.1093/ajcn/72.2.573s – ident: ref50 doi: 10.3171/jns.2004.100.2.0266 – ident: ref4 doi: 10.1126/scitranslmed.3007092 – ident: ref25 doi: 10.18858/smn.2018.9.1.5 – ident: ref64 doi: 10.1177/0148607116655448 – ident: ref52 doi: 10.1177/014860710603000271 – ident: ref42 doi: 10.1007/bf00335165 – ident: ref56 doi: 10.1097/01.ccm.0000054868.93459.e1 – ident: ref58 doi: 10.1097/01.wcb.0000066287.21705.21 – ident: ref36 doi: 10.3390/nu14020342 – ident: ref23 doi: 10.1017/s1740925x11000093 – start-page: 2073 volume-title: Neutral amino acid transport at the human blood-brain barrier year: 1986 ident: ref8 contributor: fullname: Pardridge – ident: ref34 doi: 10.1016/j.clnu.2008.06.006 – ident: ref15 doi: 10.1016/s0305-0491(96)00259-3 – ident: ref41 doi: 10.1177/0884533611434116 – ident: ref22 doi: 10.1007/s00702-014-1180-8 – ident: ref16 doi: 10.1111/j.1600-0404.1986.tb03254.x – ident: ref1 doi: 10.1111/j.1471-4159.2004.02179.x – ident: ref30 doi: 10.1016/j.clnu.2006.01.021 – ident: ref2 doi: 10.1073/pnas.0910280107 – ident: ref46 doi: 10.1097/00003246-199803000-00033 – ident: ref54 doi: 10.1164/ajrccm.153.3.8630539 – ident: ref24 doi: 10.1186/cc13962 – ident: ref61 doi: 10.1016/j.clnu.2021.05.012 – ident: ref9 doi: 10.1016/j.apmr.2005.03.022 – ident: ref5 doi: 10.1093/jn/136.1.207s – ident: ref40 doi: 10.1016/j.jcrc.2013.08.017 – start-page: 219 volume-title: Intravenous glutamate enhances edema formation after a freezing lesion year: 1990 ident: ref33 contributor: fullname: Kempski – ident: ref27 doi: 10.3390/cancers11111628 – ident: ref29 doi: 10.3390/nu12040910 – ident: ref48 doi: 10.1227/00006123-198409000-00003 – ident: ref6 doi: 10.2174/1871527317666180627120501 – ident: ref67 doi: 10.1111/apa.12838 – ident: ref65 doi: 10.1016/j.resuscitation.2019.01.007 – ident: ref32 doi: 10.1016/j.neuint.2007.04.026 – ident: ref60 doi: 10.1016/j.resuscitation.2014.12.025 – ident: ref35 doi: 10.1016/j.jinorgbio.2015.09.003 – ident: ref12 doi: 10.1016/s0003-9993(00)90137-0 – ident: ref66 doi: 10.1002/jpen.1596 – ident: ref51 doi: 10.1002/jpen.2035 – ident: ref17 doi: 10.1159/000310330 – ident: ref3 doi: 10.1089/neu.2012.2491 – start-page: 13 volume-title: Intracarotid L-arginine reverses motor evoked potential changes in experimental cerebral vasospasm year: 2007 ident: ref21 contributor: fullname: Ozüm – ident: ref18 doi: 10.1179/016164106x152052 – ident: ref47 doi: 10.1080/02699050500487571 – ident: ref10 doi: 10.3389/fneur.2015.00073 – start-page: 479 volume-title: A.S.P.E.N. position paper: parenteral nutrition glutamine supplementation year: 2011 ident: ref31 contributor: fullname: Vanek – ident: ref43 doi: 10.1136/jnnp.2004.042838 – ident: ref53 doi: 10.1080/03009734.2019.1659888 – ident: ref57 doi: 10.3390/pharmacy9030121 |
SSID | ssib044745195 |
Score | 1.90025 |
Snippet | Neuro-critically ill patients face unique challenges in nutritional support due to varying metabolic and energy demands arising from clinical situations such... |
SourceID | crossref |
SourceType | Aggregation Database |
StartPage | 84 |
Title | Neurocritical Care Nutrition: Unique Considerations and Strategies for Optimizing Energy Supply and Metabolic Support in Critically Ill Patients |
Volume | 6 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9NAEF6FcuGCWkHFo6A9cEGVi-1de-3eUJUqRQq9pFJ7svYpgsCpwDnQA7-Bv9R_xsyuX4laiXKxotVqssl82p0df_MNIe9U6cpUuCyKhTQRFyyNpJI8SnTCpHNSW-kJsp_z2QX_dJldTia3I9bSulFH-ubOupL_8SqMgV-xSvYBnu2NwgB8Bv_CEzwMz3_ysVfW0F2zAiwlgtt_q66PV_2LoM7aNeVsWW-erNl0EhGeZ3gOG8f35Q2mDaahGNB3-wzaTHPbAFJQDBsHIVz3lYLtt8KcM8z-BXnWn_fEun6hy54tjysdXv6HOm1pD2e_1j1UT76sfBL3arVCMa7t6XOwNqL_2MAdmEmkEH0bZzJSNjoC_IaHujhwMQ6dnY7sHWPtjp2PgJmOdt_QbK49xwPtd_uEYGmGSZbTr_USBSxT1LfNQxOjTTHurUOypy7CpcnbqNBChRYqb-EReYxajNi-Yf572m1pnAuv34MtDrtfEl6WeyMftpYxCo5GUc5ilzxtXUY_BqztkYmtn5E_Gzij6D3a4-yYBpTRTZRRQA4dUEYBZXRAGQ0oowFlfm6PMtqijC5rOqCMAspoh7LnZHE6XZzMoraTR6QhAI9UKXSeldwZ6WKVCWEgLjJMWGe0K4wqmFN5wQ120nKOJy4pnYG4syhYbLSybJ_s1KvaviA0kdhGUhfa5YyzOFYSzKWOCSOtyAR_Sd53_2B1HfRaqvtc9uoBc1-TJwNkD8hO82Nt30A42qi33uF_AeuokwQ |
link.rule.ids | 314,780,784,27924,27925 |
linkProvider | ISSN International Centre |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Neurocritical+Care+Nutrition%3A+Unique+Considerations+and+Strategies+for+Optimizing+Energy+Supply+and+Metabolic+Support+in+Critically+Ill+Patients&rft.jtitle=Journal+of+Neurointensive+Care&rft.au=Kim%2C+Jae+Hyun&rft.au=Choo%2C+Yoon+Hee&rft.au=Kim%2C+Moinay&rft.au=Jeon%2C+Hanwool&rft.date=2023-10-31&rft.issn=2635-5280&rft.eissn=2635-5280&rft.volume=6&rft.issue=2&rft.spage=84&rft.epage=97&rft_id=info:doi/10.32587%2Fjnic.2023.00689&rft.externalDBID=n%2Fa&rft.externalDocID=10_32587_jnic_2023_00689 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2635-5280&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2635-5280&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2635-5280&client=summon |