A Transgenic Model of Visceral Obesity and the Metabolic Syndrome - Masuzaki, Hiroaki; Paterson, Janice; Shinyama, Hiroshi; Morton, Nicholas M.; Mullins, John J.; Seckl, Jonathan R.; Flier, Jeffrey S. (Science (American Association for the Advancement of Science), 2001)
Keywords: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11^b hydroxysteroid dehydrogenase 1; 11b hydroxysteroid dehydrogenase 1; Abdomen; Adipocytes; Adipocytes - cytology; Adipocytes - pathology; Adipose Tissue; Adipose Tissue - enzymology; Adipose Tissue - metabolism; Adipose tissues; administration & dosage; Adrenocortical hormones; Animals; Biological and medical sciences; blood; Body Composition; Body fat; Cell Size; Corticosteroids; Corticosterone; Corticosterone - blood; Corticosterone - metabolism; cytology; Diabetes; Dietary Fats; Dietary Fats - administration & dosage; Disease Models, Animal; Eating; enzymology; Gene Targeting; Genes; Genetically modified mice; genetically modified organisms; genetics; Glucocorticoids; High fat diet; Humans; Hydroxysteroid Dehydrogenases; Hydroxysteroid Dehydrogenases - genetics; Hydroxysteroid Dehydrogenases - metabolism; Hyperglycemia; Hyperglycemia - metabolism; Hyperinsulinism; Hyperinsulinism - metabolism; Insulin Resistance; Leptin; Leptin - metabolism; Lipid Metabolism; Lipids; Lipids - blood; Lipoprotein Lipase; Lipoprotein Lipase - genetics; Lipoprotein Lipase - metabolism; Male; Medical sciences; Messenger RNA; Metabolic diseases; Metabolic disorders; Metabolic Syndrome; Metabolism; Mice; Mice, Transgenic; Obesity; Obesity - enzymology; Obesity - genetics; pathology; Receptors, Glucocorticoid; Receptors, Glucocorticoid - genetics; Receptors, Glucocorticoid - metabolism; Scientific Concepts; Subcutaneous fat; Transgenic animals; Viscera; Visceral fat; Weight Gain; Endocrinopathy; Animal model; Obesity; Adipose tissue; Corticosterone; Rodentia; Nutrition disorder; Transgenic animal; Gene overexpression; Cardiovascular disease; Metabolic diseases; Glucocorticoid; Vertebrata; Concomitant disease; Mammalia; Mouse; X Syndrome; Adrenal hormone; Nutritional status