Yellow Fever in Africa: Estimating the Burden of Disease and Impact of Mass Vaccination from Outbreak and Serological Data

• Published in: PLoS medicine Vol. 11; no. 5; p. e1001638
• Main Authors: Garske, Tini, Van Kerkhove, Maria D., Yactayo, Sergio, Ronveaux, Olivier, Lewis, Rosamund F., Staples, J. Erin, Perea, William, Ferguson, Neil M.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.05.2014; Public Library of Science (PLoS)
• Subjects: Africa; Africa - epidemiology; Alliances; Bayes Theorem; Biology and Life Sciences; Cause of Death; Cost of Illness; Disease; Disease Outbreaks - prevention & control; Epidemics; Estimates; Fever; Flavivirus; Geography; Humans; Immunization; Infections; Management; Mass Vaccination; Medical research; Medicine and Health Sciences; Methods; Prevention; Regression Analysis; Sensitivity analysis; Seroepidemiologic Studies; Social aspects; Tropical diseases; Vaccination; Vaccines; Yellow fever; Yellow Fever - epidemiology; Yellow Fever - mortality; Yellow Fever - prevention & control; Yellow Fever - transmission; Africa; South America; ASW, South America; Nigeria

Yellow fever is a vector-borne disease affecting humans and non-human primates in tropical areas of Africa and South America. While eradication is not feasible due to the wildlife reservoir, large scale vaccination activities in Africa during the 1940s to 1960s reduced yellow fever incidence for sev...