Cure of ADPKD by Selection for Spontaneous Genetic Repair Events in Pkd1-Mutated iPS Cells - Cheng, Li-Tao; Nagata, Shogo; Hirano, Kunio; Yamaguchi, Shinpei; Horie, Shigeo; Ainscough, Justin; Tada, Takashi (PloS one, 2012)
Keywords: Analysis; Animals; Biology; Cell division; Cell Transplantation; Chimera; Chromosomes; Clonal deletion; Cloning; Cysts; Disorders; DNA Repair; Epigenetic inheritance; epigenetics; Gene deletion; Gene therapy; Genes; Genetic aspects; Genetic disorders; genomics; Genotype & phenotype; Genotypes; Health aspects; Homologous recombination; Homology; Hybridization; Immunoglobulins; Induced Pluripotent Stem Cells; Inhibitory postsynaptic potentials; Kidney diseases; Kidney transplantation; Kidneys; Medicine; Mice; Morphology; Mutation; Patients; Pluripotency; Polycystic kidney; Polycystic Kidney, Autosomal Dominant - genetics; Polycystic Kidney, Autosomal Dominant - therapy; Polymerase chain reaction; Recombination; Recombination, Genetic; Repair; Restoration; Somatic cells; Stem cell transplantation; Stem cells; Tissue engineering; Transplantation; Treatment Outcome; TRPP Cation Channels - genetics; Tumorigenesis; Kyoto Japan; Japan