Thinking Outside a Less Intact Box: Thalamic Dopamine D2 Receptor Densities Are Negatively Related to Psychometric Creativity in Healthy Individuals

• Published in: PloS one Vol. 5; no. 5; p. e10670
• Main Authors: de Manzano, Örjan, Cervenka, Simon, Karabanov, Anke, Farde, Lars, Ullén, Fredrik
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.05.2010; Public Library of Science (PLoS)
• Subjects: Aberration; Adult; Amphetamines; Attentional bias; Batteries; Bipolar disorder; Brain research; Cerebral cortex; Channel gating; Children & youth; Childrens health; Cognitive ability; Creativity; Dopamine; Dopamine D2 receptors; Emission measurements; Female; Genetic aspects; Health; Humans; Hypotheses; Information flow; Liability; Male; Medical imaging; Mental disorders; Middle Aged; Neuroscience/Cognitive Neuroscience; Neuroscience/Experimental Psychology; Neuroscience/Psychology; Neurosciences; Neurotransmission; Personality traits; Phenols (Class of compounds); Positron emission; Positron emission tomography; Protein Binding; Psychiatry; Psychometrics; Psychopathology; Quantitative psychology; Raclopride; Radioisotopes; Receptors, Dopamine D2 - metabolism; Schizophrenia; Studies; Thalamus; Thalamus - metabolism; Tomography; Women; Sweden

Several lines of evidence support that dopaminergic neurotransmission plays a role in creative thought and behavior. Here, we investigated the relationship between creative ability and dopamine D2 receptor expression in healthy individuals, with a focus on regions where aberrations in dopaminergic f...