Synthesis and X-Ray Analysis of the (S) Enantiomer of Methyl 5-Hydroxy-3,11-di-2-pyridyl-4,5-dihydro-1H,3H-2,6-methano- 6-benz[c]azocinecarboxylate C 24 H 23 N 3 O 3 and of the Corresponding Camphanic Acid Ester C 34 H 35 N 3 O 6

• Published in: Zeitschrift für Naturforschung. B, A journal of chemical sciences Vol. 43; no. 7; pp. 901 - 910
• Main Authors: Hesse, K.-F., Holzgrabe, Ulrike, Piening, Barthold
• Format: Journal Article
• Language: English
• Published: 01.07.1988

Abstract Methyl 5-hydroxy-3,11-di-2-pyridyl-4,5-dihydro-1H,3H-2,6-methano-6-benz[c]azocinecarb-oxylate (-)-3 is synthesized by oxidative cyclization of an N-benzyl-4-piperidone, reduction and resolution with (-)-camphanic acid chloride. The structures of C 24 H 23 N 3 O 3 (-)-3 and of the correspond...