Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients - Levänen, Bettina; Bhakta, Nirav R.; Torregrosa Paredes, Patricia; Barbeau, Rebecca; Hiltbrunner, Stefanie; Pollack, Joshua L.; Sköld, C. Magnus; Svartengren, Magnus; Grunewald, Johan; Gabrielsson, Susanne; Eklund, Anders; Larsson, Britt-Marie; et al. (Journal of allergy and clinical immunology, 2013)
Keywords: Adolescent; Adult; air; Air Pollutants - toxicity; allergic asthma; Allergy and Immunology; Asthma; Asthma - genetics; Asthma - physiopathology; Biological and medical sciences; Bronchoalveolar Lavage Fluid - chemistry; Case-Control Studies; Cellulose acetate; Chronic obstructive pulmonary disease, asthma; Cytokines - genetics; Environmental Exposure; epithelial cells; exosome; exosomes; Exosomes - genetics; Female; Forced Expiratory Volume; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Gene expression; Humans; IL-13; Immunopathology; inflammation; Janus Kinases - genetics; lung function; Male; Medical sciences; microarray technology; microRNA; MicroRNAs; MicroRNAs - analysis; Mitogen-Activated Protein Kinases - genetics; patients; Pneumology; reverse transcriptase polymerase chain reaction; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; STAT Transcription Factors - genetics; Sweden; Vital Capacity; Young Adult; Sweden; BALF; IL-13; FACS; MAPK; BAL; OPLS; PCA; SUS; MFI; STAT; lung function; allergic asthma; JAK; MHCII; microRNA; KEGG; miRNA; CV-ANOVA; qPCR; VIP; exosome; PM; Signal transducer and activator of transcription; Kyoto encyclopedia of genes and genomes; Variable importance in the projections; Bronchoalveolar lavage; Janus kinase; Cross-validated ANOVA; Mean fluorescence intensity; Mitogen-activated protein kinase; MHC class II; Quantitative PCR; Fluorescence-activated cell sorting; Shared and unique structures; Particulate matter; Bronchoalveolar lavage fluid; Orthogonal projections to latent structures; Principal component analysis; Human; Lung disease; Allergy; Immunopathology; RNA interference; Respiratory disease; Cytokine; Micro RNA; Interleukin 13; Asthma; Gene silencing; Lung function; Immunology; Exosome; Bronchus disease