APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases - Fernández-Calle, Rosalía; Konings, Sabine C.; Frontiñán-Rubio, Javier; García-Revilla, Juan; Camprubí-Ferrer, Lluís; Svensson, Martina; Martinson, Isak; Boza-Serrano, Antonio; Venero, José Luís; Nielsen, Henrietta M.; Gouras, Gunnar K.; Deierborg, Tomas (Molecular neurodegeneration, 2022)
Keywords: Advertising executives; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Amyotrophic lateral sclerosis; Apolipoprotein E; Apolipoprotein E2 - genetics; Apolipoprotein E3 - genetics; Apolipoprotein E4; Apolipoprotein E4 - genetics; Apolipoproteins; Apolipoproteins E - metabolism; Autophagy; Brain; Cell interactions; Cholesterol; Chromosomes; Clinical Medicine; Clinical trials; Exercise; Gene expression; Genetic aspects; Genomes; Genotype; Genotype & phenotype; Health risk assessment; Humans; Hypotheses; Inflammation; Injuries; Klinisk medicin; Medical and Health Sciences; Medicin och hälsovetenskap; Metabolism; Movement disorders; Multiple sclerosis; Nervous system; Neurodegeneration; Neurodegenerative diseases; Neurodegenerative Diseases - genetics; Neurofibrillary tangles; Neuroinflammation; Neurologi; Neurology; Nucleotides; Parkinson's disease; Pathology; Peptides; Physiology; Plaque, Amyloid - pathology; Proteins; Review; Reviews; Risk factors; Senile plaques; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Structure-function relationships; Tau protein; tau Proteins - genetics; Traumatic brain injury; β-Amyloid; Neuroinflammation; Alzheimer’s disease; Apolipoprotein E; Neurodegeneration