基于椎管内微刺激的大鼠后肢运动脊髓功能核心区域测定

为了提高基于脊髓功能性电激励重建后肢运动功能时电极植入位置的准确性和可靠性,实验测定了大鼠后肢运动相关的脊髓功能核心区域的分布情况。此次研究利用三维扫描式椎管内微刺激技术对脊髓进行刺激,以产生髋关节、膝关节和踝关节等后肢运动,并记录诱发这些运动的脊髓内坐标。为了克服个体间差异,本文对12只SD大鼠的脊髓功能区域归一化后进行叠加,得到踝关节背屈、屈髋关节、伸髋关节和内收髋关节等运动的脊髓功能核心区域。本研究为微电子神经桥接系统用于后肢运动功能的重建提供了参考。...

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Published inSheng wu yi xue gong cheng xue za zhi Vol. 34; no. 4; pp. 622 - 626
Main Author 陈轶 马磊 杜薇 沈晓燕
Format Journal Article
LanguageChinese
English
Published 中国四川 四川大学华西医院 01.08.2017
Subjects
功能性电激励
新技术与新方法
核心区域
椎管内微刺激
运动功能
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Abstract 为了提高基于脊髓功能性电激励重建后肢运动功能时电极植入位置的准确性和可靠性,实验测定了大鼠后肢运动相关的脊髓功能核心区域的分布情况。此次研究利用三维扫描式椎管内微刺激技术对脊髓进行刺激,以产生髋关节、膝关节和踝关节等后肢运动,并记录诱发这些运动的脊髓内坐标。为了克服个体间差异,本文对12只SD大鼠的脊髓功能区域归一化后进行叠加,得到踝关节背屈、屈髋关节、伸髋关节和内收髋关节等运动的脊髓功能核心区域。本研究为微电子神经桥接系统用于后肢运动功能的重建提供了参考。
AbstractList 为了提高基于脊髓功能性电激励重建后肢运动功能时电极植入位置的准确性和可靠性，实验测定了大鼠后肢运动相关的脊髓功能核心区域的分布情况。此次研究利用三维扫描式椎管内微刺激技术对脊髓进行刺激，以产生髋关节、膝关节和踝关节等后肢运动，并记录诱发这些运动的脊髓内坐标。为了克服个体间差异，本文对 12 只 SD 大鼠的脊髓功能区域归一化后进行叠加，得到踝关节背屈、屈髋关节、伸髋关节和内收髋关节等运动的脊髓功能核心区域。本研究为微电子神经桥接系统用于后肢运动功能的重建提供了参考。
为了提高基于脊髓功能性电激励重建后肢运动功能时电极植入位置的准确性和可靠性,实验测定了大鼠后肢运动相关的脊髓功能核心区域的分布情况。此次研究利用三维扫描式椎管内微刺激技术对脊髓进行刺激,以产生髋关节、膝关节和踝关节等后肢运动,并记录诱发这些运动的脊髓内坐标。为了克服个体间差异,本文对12只SD大鼠的脊髓功能区域归一化后进行叠加,得到踝关节背屈、屈髋关节、伸髋关节和内收髋关节等运动的脊髓功能核心区域。本研究为微电子神经桥接系统用于后肢运动功能的重建提供了参考。
Author 陈轶 马磊 杜薇 沈晓燕
AuthorAffiliation 南通大学医学院生物医学工程系,江苏南通226019 南通大学电子信息学院生物电子学系,江苏南通226019
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– name: 2 南通大学 电子信息学院 生物电子学系（江苏南通 226019） Department of Bioelectronics, School of Electronic Information, Nantong University, Nantong, Jiangsu 226019, P.R.China
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DocumentTitleAlternate Measuring functional core regions of hindlimb movement control in the rat spinal cord with intraspinal microstimulation
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In order to improve the accuracy and reliability of the electrodes implant location when using spinal functional electrical stimulation to rebuild hindlimb motor function, we measured the distributions of function core regions in rat spinal cord associated with hindlimb movements. In this study, we utilized three-dimensional scanning intraspinal microstimulation technology to stimulate the rat spinal cord to generate hip, knee and ankle joint movements, and acquired the coordinates of the sites in spinal cord which evoked these movements. In this article, 12 SD rats were used to overcome the individual differences in the functional region of the spinal cord. After normalized and overlaid the messages, we obtained the function core regions in spinal cord associated with ankle dorsiflexion movement, hip flexion movement, hip extension movement and hip adduction movement. It provides a reference for rebuilding the hindlim
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为了提高基于脊髓功能性电激励重建后肢运动功能时电极植入位置的准确性和可靠性，实验测定了大鼠后肢运动相关的脊髓功能核心区域的分布情况。此次研究利用三维扫描式椎管内微刺激技术对脊髓进行刺激，以产生髋关节、膝关节和踝关节等后肢运动，并记录诱发这些运动的脊髓内坐标。为了克服个体间差异，本文对 12 只 SD...
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StartPage 622
SubjectTerms 功能性电激励
新技术与新方法
核心区域
椎管内微刺激
运动功能
Title 基于椎管内微刺激的大鼠后肢运动脊髓功能核心区域测定
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