Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study

• Published in: PloS one Vol. 13; no. 3; p. e0193770
• Main Authors: Plavén-Sigray, Pontus, Matheson, Granville James, Gustavsson, Petter, Stenkrona, Per, Halldin, Christer, Farde, Lars, Cervenka, Simon
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 15.03.2018; Public Library of Science (PLoS)
• Subjects: Adult; Aggression; Aggression - physiology; Aggressive behavior; Aggressiveness; Analysis; Antisocial personality disorder; Availability; Bayes Theorem; Bayesian analysis; Benzazepines; Biology and Life Sciences; Brain - diagnostic imaging; Brain - metabolism; Brain Mapping; Brain research; Carbon Radioisotopes; Cerebellum; Correlation; Correlation analysis; Correlation coefficient; Correlation coefficients; Councils; Dopamine; Dopamine D1 receptors; Dopamine receptors; Emission analysis; Emission measurements; Emissions; Homogeneity; Human behavior; Humans; Magnetic Resonance Imaging; Male; Males; Medical imaging; Medical research; Medical screening; Medicin och hälsovetenskap; Medicine and Health Sciences; Neostriatum; Neurosciences; NMR; Nuclear magnetic resonance; Personality; Personality - physiology; Personality Tests; Personality traits; Physical Sciences; Positron emission; Positron emission tomography; Psychiatry; Psychology; Radiopharmaceuticals; Receptors, Dopamine D1 - metabolism; Replication; Research and Analysis Methods; Social Behavior; Social desirability; Social Sciences; Studies; Tomography; Sweden

Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a...