Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study
Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a...
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| Published in | PloS one Vol. 13; no. 3; p. e0193770 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Public Library of Science
15.03.2018
Public Library of Science (PLoS) |
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| Online Access | Get full text |
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| Abstract | Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects.
Twenty-six healthy males were examined with the radioligand [11C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BPND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results.
There were no significant correlations (all p values > 0.3) between regional BPND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations.
We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BPND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. |
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| AbstractList | Background
Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects.
Materials and methods
Twenty-six healthy males were examined with the radioligand [ 11 C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BP ND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson’s correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results.
Results
There were no significant correlations (all p values > 0.3) between regional BP ND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations.
Discussion
We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BP ND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects. Twenty-six healthy males were examined with the radioligand [.sup.11 C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BP.sub.ND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results. There were no significant correlations (all p values > 0.3) between regional BP.sub.ND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations. We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BP.sub.ND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. Background Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects. Materials and methods Twenty-six healthy males were examined with the radioligand [11C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BPND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson’s correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results. Results There were no significant correlations (all p values > 0.3) between regional BPND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations. Discussion We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BPND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. Background Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects. Materials and methods Twenty-six healthy males were examined with the radioligand [.sup.11 C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BP.sub.ND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results. Results There were no significant correlations (all p values > 0.3) between regional BP.sub.ND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations. Discussion We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BP.sub.ND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects. Twenty-six healthy males were examined with the radioligand [11C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BPND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results. There were no significant correlations (all p values > 0.3) between regional BPND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations. We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BPND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects.Twenty-six healthy males were examined with the radioligand [11C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BPND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results.There were no significant correlations (all p values > 0.3) between regional BPND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations.We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BPND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. BACKGROUNDAssociations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects.MATERIALS AND METHODSTwenty-six healthy males were examined with the radioligand [11C]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BPND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D1-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results.RESULTSThere were no significant correlations (all p values > 0.3) between regional BPND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between D1-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations.DISCUSSIONWe could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BPND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. Background Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission tomography (PET) and self-rated measures of personality traits. So far, only one study has focused on the dopamine D1-receptor (D-1-R), finding a positive correlation with the trait social desirability, which is characterized by low dominant and high affiliative behavior, while physical aggression showed a negative correlation. The aim of the present study was to replicate these previous findings using a new independent sample of subjects. Materials and methods Twenty-six healthy males were examined with the radioligand [C-11]SCH-23390, and completed the Swedish universities Scales of Personality (SSP) which includes measures of social desirability and physical trait aggression. The simplified reference tissue model with cerebellum as reference region was used to calculate BPND values in the whole striatum and limbic striatum. The two regions were selected since they showed strong association between D-I-R availability and personality scores in the previous study. Pearson's correlation coefficients and replication Bayes factors were then employed to assess the replicability and robustness of previous results. Results There were no significant correlations (all p values >0.3) between regional BPND values and personality scale scores. Replication Bayes factors showed strong to moderate evidence in favor no relationship between Dl-receptor availability and social desirability (striatum BF01 = 12.4; limbic striatum BF01 = 7.2) or physical aggression scale scores (limbic striatum BF01 = 3.3), compared to the original correlations. Discussion We could not replicate the previous findings of associations between D1-R availability and either pro- or antisocial behavior as measured using the SSP. Rather, there was evidence in favor of failed replications of associations between BPND and scale scores. Potential reasons for these results are restrictive variance in both PET and personality outcomes due to high sample homogeneity, or that the previous findings were false positives. |
| Audience | Academic |
| Author | Matheson, Granville James Cervenka, Simon Stenkrona, Per Halldin, Christer Plavén-Sigray, Pontus Gustavsson, Petter Farde, Lars |
| AuthorAffiliation | 3 PET imaging Centre, Precision Medicine and Genomics, IMED Biotech unit, AstraZeneca, Karolinska Institutet, Stockholm, Sweden 2 Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden "INSERM", FRANCE 1 Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden |
| AuthorAffiliation_xml | – name: 3 PET imaging Centre, Precision Medicine and Genomics, IMED Biotech unit, AstraZeneca, Karolinska Institutet, Stockholm, Sweden – name: 1 Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden – name: "INSERM", FRANCE – name: 2 Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden |
| Author_xml | – sequence: 1 givenname: Pontus orcidid: 0000-0001-5342-5641 surname: Plavén-Sigray fullname: Plavén-Sigray, Pontus organization: Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden – sequence: 2 givenname: Granville James surname: Matheson fullname: Matheson, Granville James organization: Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden – sequence: 3 givenname: Petter surname: Gustavsson fullname: Gustavsson, Petter organization: Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden – sequence: 4 givenname: Per surname: Stenkrona fullname: Stenkrona, Per organization: Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden – sequence: 5 givenname: Christer surname: Halldin fullname: Halldin, Christer organization: Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden – sequence: 6 givenname: Lars surname: Farde fullname: Farde, Lars organization: PET imaging Centre, Precision Medicine and Genomics, IMED Biotech unit, AstraZeneca, Karolinska Institutet, Stockholm, Sweden – sequence: 7 givenname: Simon surname: Cervenka fullname: Cervenka, Simon organization: Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE, Stockholm, Sweden |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29543812$$D View this record in MEDLINE/PubMed https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-440724$$DView record from Swedish Publication Index http://kipublications.ki.se/Default.aspx?queryparsed=id:137950048$$DView record from Swedish Publication Index |
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| CitedBy_id | crossref_primary_10_3390_app132111719 crossref_primary_10_3390_nu14071379 crossref_primary_10_3390_biom10121633 crossref_primary_10_1371_journal_pone_0209584 crossref_primary_10_1111_add_16144 crossref_primary_10_1007_s11920_019_1011_6 crossref_primary_10_3389_fncel_2021_696834 |
| Cites_doi | 10.1016/j.neuroimage.2011.09.015 10.1037/a0036731 10.1006/game.1995.1027 10.1037/0022-3514.46.3.598 10.1126/science.aac4716 10.1016/S0149-7634(99)00063-9 10.1016/j.neuroimage.2009.12.006 10.1016/j.euroneuro.2016.02.010 10.1016/j.eurpsy.2005.05.004 10.1034/j.1600-0447.2000.102003217.x 10.1038/sj.npp.1380111 10.1038/483531a 10.1016/j.neuroimage.2014.08.018 10.1016/j.neuroimage.2006.10.042 10.1016/j.neuroimage.2010.06.031 10.1002/syn.20545 10.1016/0883-2889(86)90044-4 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2018 Public Library of Science 2018 Plavén-Sigray et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2018 Plavén-Sigray et al 2018 Plavén-Sigray et al |
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| DOI | 10.1371/journal.pone.0193770 |
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| DocumentTitleAlternate | D1-R and social behavior: Replication |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Competing Interests: The authors declare no conflicts of interest related to this work. SC has received grant support from AstraZeneca as co-investigator, and has served as a one-off speaker for Roche and Otsuka Pharmaceuticals. LF is partially employed at the AstraZeneca PET imaging Centre at Karolinska Institutet. This does not alter our adherence to PLOS ONE policies on sharing data and materials. |
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| References | A Egerton (ref3) 2010; 53 MH Couppis (ref10) 2008; 62 P Plavén-Sigray (ref9) 2014; 102 CG Begley (ref15) 2012; 483 H Hall (ref7) 1994; 11 D Vallone (ref8) 2000; 24 M Jenkinson (ref13) 2012; 62 SJ Reeves (ref2) 2007; 34 C Halldin (ref11) 1986; 37 JP Gustavsson (ref12) 2000; 102 DL Paulhus (ref6) 1984; 46 S Cervenka (ref4) 2010; 50 DJ Benjamin (ref17) 2017 (ref16) 2015; 349 J Berg (ref18) 1995; 10 CL Huang (ref1) 2006; 21 F Caravaggio (ref5) 2016; 26 J Verhagen (ref14) 2014; 143 |
| References_xml | – volume: 62 start-page: 782 year: 2012 ident: ref13 article-title: Fsl publication-title: Neuroimage doi: 10.1016/j.neuroimage.2011.09.015 contributor: fullname: M Jenkinson – volume: 143 start-page: 1457 year: 2014 ident: ref14 article-title: Bayesian tests to quantify the result of a replication attempt publication-title: Journal of Experimental Psychology: General doi: 10.1037/a0036731 contributor: fullname: J Verhagen – volume: 10 start-page: 122 year: 1995 ident: ref18 article-title: Trust, reciprocity, and social history publication-title: Games and economic behavior doi: 10.1006/game.1995.1027 contributor: fullname: J Berg – volume: 46 start-page: 598 year: 1984 ident: ref6 article-title: Two-component models of socially desirable responding publication-title: Journal of personality and social psychology doi: 10.1037/0022-3514.46.3.598 contributor: fullname: DL Paulhus – volume: 349 start-page: aac4716 year: 2015 ident: ref16 article-title: Estimating the reproducibility of psychological science publication-title: Science doi: 10.1126/science.aac4716 – volume: 24 start-page: 125 year: 2000 ident: ref8 article-title: Structure and function of dopamine receptors publication-title: Neuroscience & Biobehavioral Reviews doi: 10.1016/S0149-7634(99)00063-9 contributor: fullname: D Vallone – volume: 50 start-page: 323 year: 2010 ident: ref4 article-title: Association between striatal and extrastriatal dopamine D2-receptor binding and social desirability publication-title: Neuroimage doi: 10.1016/j.neuroimage.2009.12.006 contributor: fullname: S Cervenka – volume: 26 start-page: 644 year: 2016 ident: ref5 article-title: Exploring personality traits related to dopamine D2/3 receptor availability in striatal subregions of humans publication-title: European Neuropsychopharmacology doi: 10.1016/j.euroneuro.2016.02.010 contributor: fullname: F Caravaggio – volume: 21 start-page: 62 year: 2006 ident: ref1 article-title: The association between the Lie scale of the Maudsley personality inventory and striatal dopamine D2/D3 receptor availability of healthy Chinese community subjects publication-title: European Psychiatry: The Journal of the Association of European Psychiatrists doi: 10.1016/j.eurpsy.2005.05.004 contributor: fullname: CL Huang – volume: 102 start-page: 217 year: 2000 ident: ref12 article-title: Swedish universities Scales of Personality (SSP): construction, internal consistency and normative data publication-title: Acta psychiatrica Scandinavica doi: 10.1034/j.1600-0447.2000.102003217.x contributor: fullname: JP Gustavsson – volume: 11 start-page: 245 year: 1994 ident: ref7 article-title: Distribution of D1-and D2-dopamine receptors, and dopamine and its metabolites in the human brain publication-title: Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology doi: 10.1038/sj.npp.1380111 contributor: fullname: H Hall – volume: 483 start-page: 531 year: 2012 ident: ref15 article-title: Drug development: Raise standards for preclinical cancer research publication-title: Nature doi: 10.1038/483531a contributor: fullname: CG Begley – volume: 102 start-page: 590 year: 2014 ident: ref9 article-title: Dopamine D1 receptor availability is related to social behavior: A positron emission tomography study publication-title: Neuroimage doi: 10.1016/j.neuroimage.2014.08.018 contributor: fullname: P Plavén-Sigray – year: 2017 ident: ref17 article-title: Redefine statistical significance publication-title: Nature Human Behaviour contributor: fullname: DJ Benjamin – volume: 34 start-page: 1782 year: 2007 ident: ref2 article-title: Striatal dopamine (D2) receptor availability predicts socially desirable responding publication-title: NeuroImage doi: 10.1016/j.neuroimage.2006.10.042 contributor: fullname: SJ Reeves – volume: 53 start-page: 777 year: 2010 ident: ref3 article-title: Truth, lies or self-deception? Striatal D(2/3) receptor availability predicts individual differences in social conformity publication-title: NeuroImage doi: 10.1016/j.neuroimage.2010.06.031 contributor: fullname: A Egerton – volume: 62 start-page: 715 year: 2008 ident: ref10 article-title: Differences in aggressive behavior and in the mesocorticolimbic DA system between A/J and BALB/cJ mice publication-title: Synapse doi: 10.1002/syn.20545 contributor: fullname: MH Couppis – volume: 37 start-page: 1039 year: 1986 ident: ref11 article-title: Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography publication-title: Int J Rad Appl Instrum [A] doi: 10.1016/0883-2889(86)90044-4 contributor: fullname: C Halldin |
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| Snippet | Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron emission... Background Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron... BACKGROUNDAssociations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron... Background Associations between dopamine receptor levels and pro- and antisocial behavior have previously been demonstrated in human subjects using positron... |
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| SubjectTerms | Adult Aggression Aggression - physiology Aggressive behavior Aggressiveness Analysis Antisocial personality disorder Availability Bayes Theorem Bayesian analysis Benzazepines Biology and Life Sciences Brain - diagnostic imaging Brain - metabolism Brain Mapping Brain research Carbon Radioisotopes Cerebellum Correlation Correlation analysis Correlation coefficient Correlation coefficients Councils Dopamine Dopamine D1 receptors Dopamine receptors Emission analysis Emission measurements Emissions Homogeneity Human behavior Humans Magnetic Resonance Imaging Male Males Medical imaging Medical research Medical screening Medicin och hälsovetenskap Medicine and Health Sciences Neostriatum Neurosciences NMR Nuclear magnetic resonance Personality Personality - physiology Personality Tests Personality traits Physical Sciences Positron emission Positron emission tomography Psychiatry Psychology Radiopharmaceuticals Receptors, Dopamine D1 - metabolism Replication Research and Analysis Methods Social Behavior Social desirability Social Sciences Studies Tomography |
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| Title | Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study |
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