Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo - Pajak, Aleksandra; Laine, Isabelle; Clemente, Paula; El-Fissi, Najla; Schober, Florian A.; Maffezzini, Camilla; Calvo-Garrido, Javier; Wibom, Rolf; Filograna, Roberta; Dhir, Ashish; Wedell, Anna; Freyer, Christoph; et al. (PLoS genetics, 2019)
Keywords: Aging; Animals; Antisense RNA; Biochemistry; Biology; Biology and Life Sciences; Biophysics; CRISPR; Cytoplasm; DEAD-box RNA Helicases - genetics; DEAD-box RNA Helicases - metabolism; Deoxyribonucleic acid; DNA; DNA helicase; DNA-Directed RNA Polymerases - genetics; DNA-Directed RNA Polymerases - metabolism; Double-stranded RNA; Drosophila melanogaster - genetics; Drosophila melanogaster - metabolism; Drosophila Proteins - genetics; Drosophila Proteins - metabolism; Female; Gene expression; Genetic research; Genomes; Helicases; Hospitals; Insects; Laboratories; Male; Mammals; Medicine; Metabolic disorders; Mitochondria; Mitochondrial DNA; Molecular modelling; Molecular structure; mRNA stability; Neoplasm Proteins - genetics; Neoplasm Proteins - metabolism; Phosphorylase; Phosphorylases; Physiology; Poly(A); Polyadenylation; Polynucleotide adenylyltransferase; Polynucleotide phosphorylase; Polyribonucleotide Nucleotidyltransferase - genetics; Polyribonucleotide Nucleotidyltransferase - metabolism; Research and analysis methods; RNA helicase; RNA interference; RNA Stability; RNA, Antisense - chemistry; RNA, Antisense - metabolism; RNA, Double-Stranded - chemistry; RNA, Double-Stranded - metabolism; RNA, Mitochondrial - chemistry; RNA, Mitochondrial - metabolism; Structure; Supervision; Surgery; Transcription; Sweden