Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial - Bergman, Peter; Blennow, Ola; Hansson, Lotta; Mielke, Stephan; Nowak, Piotr; Chen, Puran; Söderdahl, Gunnar; Österborg, Anders; Smith, C. I. Edvard; Wullimann, David; Vesterbacka, Jan; Lindgren, Gustaf; et al. (EBioMedicine, 2021)
Keywords: Adenine - adverse effects; Adenine - analogs & derivatives; Adenine - therapeutic use; Advanced Basic Science; Antibodies, Viral - blood; BNT162 Vaccine - adverse effects; BNT162 Vaccine - immunology; CAR-T; chronic lymphocytic leukemia; COVID-19 - prevention & control; Female; Hematopoietic Stem Cell Transplantation; HIV; human stem-cell transplantation; Humans; Immunocompromised Host - immunology; Immunocompromised patients; Immunogenicity, Vaccine - immunology; Immunotherapy, Adoptive; Internal Medicine; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; mRNA BNT162b2 vaccine; Mycophenolic Acid - adverse effects; Mycophenolic Acid - therapeutic use; Organ Transplantation; Piperidines - adverse effects; Piperidines - therapeutic use; Primary Immunodeficiency; Primary Immunodeficiency Diseases - immunology; Prospective Studies; Research paper; SARS-CoV-2 - immunology; Seroconversion; solid organ transplantation; Spike Glycoprotein, Coronavirus - immunology; Vaccination - adverse effects; Vaccine Efficacy; human stem-cell transplantation; PP; CLL; CAR T; ITT; PID; Primary Immunodeficiency; mPP; Immunocompromised patients; mRNA BNT162b2 vaccine; COVID-19; SARS-CoV-2; chronic lymphocytic leukemia; HIV; CAR-T; solid organ transplantation; SOT; HSCT; Per protocol; Primary immunodeficiency disorders; Allogeneic hematopoietic stem cell transplantation; Intention to treat; Coronavirus disease 2019; Chimeric antigen receptor T; Severe acute respiratory syndrome coronavirus 2; Modified per protocol; Human immunodeficiency virus