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Keywords: 631/154; 631/326/596; 692/699/255/234/2513/1551; Adolescent; Adult; Amino acids; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral agents; Antiviral Agents - blood; Antiviral Agents - chemistry; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; Biochemical genetics; Biological and medical sciences; Carbamates; Cell Line; Chlorocebus aethiops; Drug Resistance, Viral; Drug therapy; Female; Gastroenterology. Liver. Pancreas. Abdomen; Genetic aspects; Genetics; Genotype; Genotype & phenotype; Genotypes; HeLa Cells; Hepacivirus - drug effects; Hepatitis C; Hepatitis C - drug therapy; Hepatitis C - virology; Hepatitis C virus; Human viral diseases; Humanities and Social Sciences; Humans; Imidazoles - blood; Imidazoles - chemistry; Imidazoles - pharmacology; Infectious diseases; Inhibitory Concentration 50; letter; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Middle Aged; multidisciplinary; Multidisciplinary Sciences; Other diseases. Semiology; Pharmacology. Drug treatments; Pyrrolidines; RNA polymerases; Science; Science & Technology; Science & Technology - Other Topics; Science (multidisciplinary); Testing; Time Factors; Valine - analogs & derivatives; Vero Cells; Viral diseases; Viral diseases of the digestive system; Viral Load - drug effects; Viral Nonstructural Proteins - antagonists & inhibitors; Young Adult; United States; DOMAIN; HEPATITIS-C VIRUS; RNA; NONSTRUCTURAL PROTEINS; Drug; Pharmacotherapy; Hepatic disease; In vitro; Infection; Virus; Chronic; Treatment; Viral disease; Digestive diseases; Antiviral; Flaviviridae; Hepatitis C virus; Hepacivirus; Viral hepatitis C