Transcription factor induced conversion of human fibroblasts towards the hair cell lineage - Duran Alonso, María Beatriz; Lopez Hernandez, Iris; de la Fuente, Miguel Angel; Garcia-Sancho, Javier; Giraldez, Fernando; Schimmang, Thomas (PloS one, 2018)
Keywords: Acoustics; Basic Helix-Loop-Helix Transcription Factors - genetics; Basic Helix-Loop-Helix Transcription Factors - metabolism; Biology and Life Sciences; Biomarkers - metabolism; Brain; Cardiomyocytes; Cell lineage; Cell Lineage - drug effects; Cell Lineage - genetics; Cell Lineage - physiology; Cell Transdifferentiation - drug effects; Cell Transdifferentiation - genetics; Cell Transdifferentiation - physiology; Cells (biology); Cells, Cultured; Cochlea; Cèl·lules acústiques; Direct conversion; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Embryo cells; Embryonic stem cells; Epidermal Growth Factor - pharmacology; Epigenetics; Fibroblasts; Fibroblasts - cytology; Fibroblasts - drug effects; Fibroblasts - metabolism; Gene expression; Gene Expression - drug effects; Genes; Hair; Hair cells; Hair Cells, Auditory - cytology; Hair Cells, Auditory - drug effects; Hair Cells, Auditory - metabolism; Hearing loss; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Humans; Inhibitory postsynaptic potentials; Mammals; Math1 protein; Mechanoreceptors; Medicine and Health Sciences; Myosin VIIa; Myosins - genetics; Nanoparticles; Neonates; Pluripotency; Progenitor cells; Receptors; Recombinant Proteins - genetics; Recombinant Proteins - metabolism; Regeneration; Research and Analysis Methods; Restoration; Risk factors; RNA, Messenger - genetics; RNA, Messenger - metabolism; Somatic cells; Stem cells; Transcription activation; Transcription Factor Brn-3C - genetics; Transcription Factor Brn-3C - metabolism; Transcription factors; Transcription Factors - genetics; Transcription Factors - metabolism; Tretinoin - pharmacology; United States--US; Grand Island New York; Spain