Altered deposition of inhaled nanoparticles in subjects with chronic obstructive pulmonary disease - Jakobsson, Jonas K F; Aaltonen, H Laura; Nicklasson, Hanna; Gudmundsson, Anders; Rissler, Jenny; Wollmer, Per; Löndahl, Jakob (BMC pulmonary medicine, 2018)
Keywords: adult; Aerosols; Aged; Air pollution; asymptomatic disease; bioaccumulation; breath holding; bronchodilating agent; carbon monoxide; Case-Control Studies; Chronic obstructive lung disease; Chronic obstructive pulmonary disease; Clinical Medicine; computer assisted tomography; controlled study; COPD and occupational lung disease; Critical Care Medicine; Development and progression; Disease; Efficiency; Emphysema; Female; forced expiratory volume; Health aspects; Health care; Human; Humans; In vivo study; Inhalation Exposure; Intensive; Internal Medicine; Klinisk medicin; Lung deposition; lung diffusion capacity; Lung diseases; lung emphysema; lung function test; Lungmedicin och allergi; Lungs; major clinical study; Male; measurement; Medical and Health Sciences; Medicin och hälsovetenskap; Medicine; Medicine & Public Health; Middle Aged; nanoparticle; Nanoparticles; Nanoparticles - administration & dosage; Nanoparticles - analysis; Obstructive lung disease; Outdoor air quality; Particle size; Physiological aspects; Pneumology/Respiratory System; Pulmonary Disease, Chronic Obstructive - physiopathology; Pulmonary Emphysema - physiopathology; Pulmonology; Research Article; Respiratory diseases; Respiratory Function Tests; Respiratory Medicine and Allergy; Risk factors; smoking; Smoking - physiopathology; Studies; Sweden; Tissue Distribution; Tomography; vital capacity; volumetry; Sweden; Nanoparticles; Human; Lung deposition; In vivo study; Chronic obstructive pulmonary disease; Inhalation exposure; Emphysema