New common variants affecting susceptibility to basal cell carcinoma

In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 × 10−9). A varian...

Full description

Saved in:
Bibliographic Details
Published inNature genetics Vol. 41; no. 8; pp. 909 - 914
Main Authors Gudjonsson, Sigurjon A, Sigurdsson, Asgeir, Bonenkamp, Johannes J, Magnusdottir, Droplaug N, Thorisdottir, Kristin, Masson, Gisli, Juberias, Pablo, Rodolfo, Monica, Frigge, Michael L, Nelson, Heather H, Hansson, Johan, Saemundsdottir, Jona, Pehamberger, Hubert, Stacey, Simon N, Corredera, Cristina, Sigurgeirsson, Bardur, Gurzau, Eugene, Nagore, Eduardo, Gulcher, Jeffrey R, Gudmundsson, Julius, Benediktsdottir, Kristrun R, Höiom, Veronica, Thorsteinsdottir, Unnur, Fuentelsaz, Victoria, Saez, Berta, Mayordomo, José I, Thorleifsson, Gudmar, Wendt, Judith, Hochleitner, Pia, Kong, Augustine, Jakobsdottir, Margret, Soriano, Virtudes, Olafsson, Jon H, Stefansson, Kari, Rivoltini, Licia, Santinami, Mario, Aben, Katja K H, Karagas, Margaret R, Maurichi, Andrea, Blondal, Thorarinn, Botella-Estrada, Rafael, Gilaberte, Yolanda, Rudnai, Peter, Grasa, Matilde, van Rossum, Michelle M, Okamoto, Ichiro, Hemminki, Kari, Gudbjartsson, Daniel F, Holm, Hilma, Gretarsdottir, Solveig, Ragnarsson, Rafn, Kumar, Rajiv, Di Mauro, Maria G, Kiemeney, Lambertus A, Rafnar, Thorunn, Koppova, Kvetoslava, Lindblom, Annika, de Vries, Esther, Bjarnason, Hjördis, Kristjansson, Kristleifur, Bjornsdottir, Gyda, Sulem, Patrick, Steinthorsdottir, Valgerdur, Scherer, Dominique
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.08.2009
Nature Publishing Group
Subjects
Agriculture
Animal Genetics and Genomics
Basal cell carcinoma
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cancer
Cancer Research
Carcinoma, Basal Cell - complications
Carcinoma, Basal Cell - genetics
Carcinoma, Squamous Cell - genetics
Cells
Chromosomes, Human, Pair 7 - genetics
Chromosomes, Human, Pair 9 - genetics
Coronary Artery Disease - complications
Coronary Artery Disease - genetics
Cyclin-dependent kinases
Dermatology
Disease susceptibility
Environmental health
Fundamental and applied biological sciences. Psychology
Gene Function
Genetic aspects
Genetic Predisposition to Disease
Genetics of eukaryotes. Biological and molecular evolution
Genome-Wide Association Study
Health aspects
Human Genetics
Humans
Keratin
Keratin-5 - genetics
letter
Linkage Disequilibrium - genetics
Medical sciences
Medicin och hälsovetenskap
Melanoma
Melanoma - pathology
Membrane Proteins - genetics
Molecular Sequence Data
Multivariate analysis
Neoplasm Proteins - genetics
Pigmentation
Polymorphism, Single Nucleotide - genetics
Risk factors
Sample size
Single nucleotide polymorphisms
Skin Neoplasms - complications
Skin Neoplasms - genetics
Tumors of the skin and soft tissue. Premalignant lesions
Ultraviolet radiation
Sweden
Spain
Variant
Skin disease
Basal cell carcinoma
Malignant tumor
Cancer
Online AccessGet full text

Cover

Abstract In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 × 10−9). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 × 10−9), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 × 10−10). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
AbstractList In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC) 1 , we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 ( KRT5 ) gene, affects risk of BCC (OR = 1.35, P = 2.1 × 10 −9 ). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 × 10 −9 ), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 × 10 −10 ). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT - CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 × 10^sup -9^). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 × 10^sup -9^), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 × 10^sup -10^). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma. [PUBLICATION ABSTRACT]
Simon Stacey and colleagues report several new susceptibility variants for basal cell carcinoma, including coding variants in KRT5 , a variant at 9p21 near CDKN2A and CDKN2B and a variant at 7q32 near KLF14 . The latter is an imprinted gene, and the effect at this locus is dependent on the parental origin of the risk allele. In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC) 1 , we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 ( KRT5 ) gene, affects risk of BCC (OR = 1.35, P = 2.1 × 10 −9 ). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 × 10 −9 ), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 × 10 −10 ). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT - CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 x 10(-9)). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 x 10(-9)), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 x 10(-10)). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 10 super(-9)). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 10 super(-9)), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 10 super(-10)). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC) (1), we describe here several new susceptibility variants. SNP rs11170164, encoding a G1 38E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 x [10.sup.-9]). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P= 6.9 x [10.sup.-9]), as does rs157935M at 7832 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 x [10.sup.10]). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTMIL locus confers susceptibility to BCC but protects against melanoma.
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 × 10−9). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 × 10−9), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 × 10−10). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
Audience Academic
Author Masson, Gisli
Thorleifsson, Gudmar
Mayordomo, José I
Höiom, Veronica
Kumar, Rajiv
Santinami, Mario
Gurzau, Eugene
Koppova, Kvetoslava
Nelson, Heather H
Olafsson, Jon H
Jakobsdottir, Margret
Rafnar, Thorunn
Scherer, Dominique
Bjarnason, Hjördis
Juberias, Pablo
Wendt, Judith
Hansson, Johan
van Rossum, Michelle M
Stefansson, Kari
Di Mauro, Maria G
Lindblom, Annika
Sigurgeirsson, Bardur
Aben, Katja K H
Sigurdsson, Asgeir
Gudmundsson, Julius
Gretarsdottir, Solveig
Rivoltini, Licia
Botella-Estrada, Rafael
Stacey, Simon N
Thorisdottir, Kristin
Bjornsdottir, Gyda
Hemminki, Kari
Bonenkamp, Johannes J
Maurichi, Andrea
Gulcher, Jeffrey R
Pehamberger, Hubert
Thorsteinsdottir, Unnur
Soriano, Virtudes
Okamoto, Ichiro
Grasa, Matilde
de Vries, Esther
Karagas, Margaret R
Steinthorsdottir, Valgerdur
Gudbjartsson, Daniel F
Rudnai, Peter
Benediktsdottir, Kristrun R
Holm, Hilma
Nagore, Eduardo
Rodolfo, Monica
Kong, Augustine
Saez, Berta
Ragnarsson, Rafn
Sulem, Patrick
Fuentelsaz, Victoria
Corredera, Cristina
Saemundsdottir, Jona
Kristjansson, Kristleifur
Frigge,
AuthorAffiliation 5 Division of Molecular Genetic Epidemiology, German Cancer Research Centre, Heidelberg, Germany
12 Health Science Institute, Nanotechnology Institute of Aragon, Zaragoza, Spain
1 deCODE genetics, Reykjavik, Iceland
18 Department of Epidemiology, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
24 Immunotherapy of Human Tumours Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
19 Comprehensive Cancer Centre IKO, Nijmegen, The Netherlands
9 Department of Dermatology, Instituto Valenciano de Oncologia, Valencia, Spain
15 Department of Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
27 Division of Medical Oncology University Hospital, Zaragoza, Spain
16 Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
2 Department of Dermatology, Landspitali, University of Iceland, Reykjavik, Iceland
4 Department of Plastic Surgery, Landspitali, University of Iceland, Reykjavik,
AuthorAffiliation_xml – name: 29 Division of Epidemiology and Community Health, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
– name: 13 Division of Dermatology, San Jorge General Hospital, Huesca, Spain
– name: 19 Comprehensive Cancer Centre IKO, Nijmegen, The Netherlands
– name: 14 Department of Oncology Pathology, Cancer Centre Karolinska, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
– name: 20 Department of Public Health, Erasmus Medical Centre, Rotterdam, The Netherlands
– name: 11 Division of Dermatology University Hospital, Zaragoza, Spain
– name: 25 Melanoma Genetics Group, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
– name: 18 Department of Epidemiology, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
– name: 12 Health Science Institute, Nanotechnology Institute of Aragon, Zaragoza, Spain
– name: 10 Department of Oncology, Instituto Valenciano de Oncologia, Valencia, Spain
– name: 17 Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
– name: 15 Department of Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
– name: 16 Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
– name: 28 Section of Biostatistics and Epidemiology, Department of Community and Family Medicine, and the Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, USA
– name: 8 State Health Institute, Banska Bystrica, Slovakia
– name: 7 Environmental Health Centre, Cluj, RO-Cluj-Napoca, Romania
– name: 5 Division of Molecular Genetic Epidemiology, German Cancer Research Centre, Heidelberg, Germany
– name: 4 Department of Plastic Surgery, Landspitali, University of Iceland, Reykjavik, Iceland
– name: 6 National Institute of Environmental Health, Budapest, Hungary
– name: 9 Department of Dermatology, Instituto Valenciano de Oncologia, Valencia, Spain
– name: 1 deCODE genetics, Reykjavik, Iceland
– name: 27 Division of Medical Oncology University Hospital, Zaragoza, Spain
– name: 21 Melanoma and Sarcoma Surgery Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
– name: 3 Department of Pathology, Landspitali, University of Iceland, Reykjavik, Iceland
– name: 2 Department of Dermatology, Landspitali, University of Iceland, Reykjavik, Iceland
– name: 22 Department of Immunohematology and Transfusion Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
– name: 26 Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
– name: 23 Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
– name: 24 Immunotherapy of Human Tumours Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
Author_xml – givenname: Sigurjon A
  surname: Gudjonsson
  fullname: Gudjonsson, Sigurjon A
  organization: deCODE genetics
– givenname: Asgeir
  surname: Sigurdsson
  fullname: Sigurdsson, Asgeir
  organization: deCODE genetics
– givenname: Johannes J
  surname: Bonenkamp
  fullname: Bonenkamp, Johannes J
  organization: Department of Surgery, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre
– givenname: Droplaug N
  surname: Magnusdottir
  fullname: Magnusdottir, Droplaug N
  organization: deCODE genetics
– givenname: Kristin
  surname: Thorisdottir
  fullname: Thorisdottir, Kristin
  organization: Departments of Dermatology, University of Iceland Department of Plastic Surgery, Landspitali, University of Iceland
– givenname: Gisli
  surname: Masson
  fullname: Masson, Gisli
  organization: deCODE genetics
– givenname: Pablo
  surname: Juberias
  fullname: Juberias, Pablo
  organization: Division of Dermatology University Hospital
– givenname: Monica
  surname: Rodolfo
  fullname: Rodolfo, Monica
  organization: Immunotherapy of Human Tumours Unit, Fondazione IRCCS Istituto Nazionale Tumori Melanoma Genetics Group, Fondazione IRCCS Istituto Nazionale Tumori
– givenname: Michael L
  surname: Frigge
  fullname: Frigge, Michael L
  organization: deCODE genetics
– givenname: Heather H
  surname: Nelson
  fullname: Nelson, Heather H
  organization: Division of Epidemiology and Community Health, Masonic Cancer Center, University of Minnesota
– givenname: Johan
  surname: Hansson
  fullname: Hansson, Johan
  organization: Department of Oncology Pathology, Cancer Centre Karolinska, Karolinska Institutet, Karolinska University Hospital Solna
– givenname: Jona
  surname: Saemundsdottir
  fullname: Saemundsdottir, Jona
  organization: deCODE genetics
– givenname: Hubert
  surname: Pehamberger
  fullname: Pehamberger, Hubert
  organization: Department of Dermatology, Division of General Dermatology, Medical University of Vienna
– givenname: Simon N
  surname: Stacey
  fullname: Stacey, Simon N
  organization: deCODE genetics
– givenname: Cristina
  surname: Corredera
  fullname: Corredera, Cristina
  organization: Division of Dermatology University Hospital
– givenname: Bardur
  surname: Sigurgeirsson
  fullname: Sigurgeirsson, Bardur
  organization: Departments of Dermatology, University of Iceland
– givenname: Eugene
  surname: Gurzau
  fullname: Gurzau, Eugene
  organization: Environmental Health Centre
– givenname: Eduardo
  surname: Nagore
  fullname: Nagore, Eduardo
  organization: Department of Dermatology, Instituto Valenciano de Oncologia
– givenname: Jeffrey R
  surname: Gulcher
  fullname: Gulcher, Jeffrey R
  organization: deCODE genetics
– givenname: Julius
  surname: Gudmundsson
  fullname: Gudmundsson, Julius
  organization: deCODE genetics
– givenname: Kristrun R
  surname: Benediktsdottir
  fullname: Benediktsdottir, Kristrun R
  organization: Department of Pathology, University of Iceland
– givenname: Veronica
  surname: Höiom
  fullname: Höiom, Veronica
  organization: Department of Oncology Pathology, Cancer Centre Karolinska, Karolinska Institutet, Karolinska University Hospital Solna
– givenname: Unnur
  surname: Thorsteinsdottir
  fullname: Thorsteinsdottir, Unnur
  organization: deCODE genetics
– givenname: Victoria
  surname: Fuentelsaz
  fullname: Fuentelsaz, Victoria
  organization: Division of Dermatology University Hospital
– givenname: Berta
  surname: Saez
  fullname: Saez, Berta
  organization: Health Science Institute, Nanotechnology Institute of Aragon
– givenname: José I
  surname: Mayordomo
  fullname: Mayordomo, José I
  organization: Health Science Institute, Nanotechnology Institute of Aragon Division of Medical Oncology University Hospital
– givenname: Gudmar
  surname: Thorleifsson
  fullname: Thorleifsson, Gudmar
  organization: deCODE genetics
– givenname: Judith
  surname: Wendt
  fullname: Wendt, Judith
  organization: Department of Dermatology, Division of General Dermatology, Medical University of Vienna
– givenname: Pia
  surname: Hochleitner
  fullname: Hochleitner, Pia
  organization: Department of Dermatology, Division of General Dermatology, Medical University of Vienna
– givenname: Augustine
  surname: Kong
  fullname: Kong, Augustine
  organization: deCODE genetics
– givenname: Margret
  surname: Jakobsdottir
  fullname: Jakobsdottir, Margret
  organization: deCODE genetics
– givenname: Virtudes
  surname: Soriano
  fullname: Soriano, Virtudes
  organization: Department of Oncology, Instituto Valenciano de Oncologia
– givenname: Jon H
  surname: Olafsson
  fullname: Olafsson, Jon H
  organization: Departments of Dermatology, University of Iceland Department of Pathology, University of Iceland Department of Plastic Surgery, Landspitali, University of Iceland
– givenname: Kari
  surname: Stefansson
  fullname: Stefansson, Kari
  organization: deCODE genetics
– givenname: Licia
  surname: Rivoltini
  fullname: Rivoltini, Licia
  organization: Immunotherapy of Human Tumours Unit, Fondazione IRCCS Istituto Nazionale Tumori
– givenname: Mario
  surname: Santinami
  fullname: Santinami, Mario
  organization: Melanoma and Sarcoma Surgery Unit, Fondazione IRCCS Istituto Nazionale Tumori
– givenname: Katja K H
  surname: Aben
  fullname: Aben, Katja K H
  organization: Department of Epidemiology, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre Comprehensive Cancer Centre IKO
– givenname: Margaret R
  surname: Karagas
  fullname: Karagas, Margaret R
  organization: Section of Biostatistics and Epidemiology, Department of Community and Family Medicine, and the Norris Cotton Cancer Center, Dartmouth Medical School
– givenname: Andrea
  surname: Maurichi
  fullname: Maurichi, Andrea
  organization: Melanoma and Sarcoma Surgery Unit, Fondazione IRCCS Istituto Nazionale Tumori
– givenname: Thorarinn
  surname: Blondal
  fullname: Blondal, Thorarinn
  organization: deCODE genetics
– givenname: Rafael
  surname: Botella-Estrada
  fullname: Botella-Estrada, Rafael
  organization: Department of Dermatology, Instituto Valenciano de Oncologia
– givenname: Yolanda
  surname: Gilaberte
  fullname: Gilaberte, Yolanda
  organization: Division of Dermatology, San Jorge General Hospital
– givenname: Peter
  surname: Rudnai
  fullname: Rudnai, Peter
  organization: National Institute of Environmental Health
– givenname: Matilde
  surname: Grasa
  fullname: Grasa, Matilde
  organization: Division of Dermatology University Hospital
– givenname: Michelle M
  surname: van Rossum
  fullname: van Rossum, Michelle M
  organization: Department of Dermatology, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre
– givenname: Ichiro
  surname: Okamoto
  fullname: Okamoto, Ichiro
  organization: Department of Dermatology, Division of General Dermatology, Medical University of Vienna
– givenname: Kari
  surname: Hemminki
  fullname: Hemminki, Kari
  organization: Division of Molecular Genetic Epidemiology, German Cancer Research Centre
– givenname: Daniel F
  surname: Gudbjartsson
  fullname: Gudbjartsson, Daniel F
  organization: deCODE genetics
– givenname: Hilma
  surname: Holm
  fullname: Holm, Hilma
  organization: deCODE genetics
– givenname: Solveig
  surname: Gretarsdottir
  fullname: Gretarsdottir, Solveig
  organization: deCODE genetics
– givenname: Rafn
  surname: Ragnarsson
  fullname: Ragnarsson, Rafn
  organization: Department of Plastic Surgery, Landspitali, University of Iceland
– givenname: Rajiv
  surname: Kumar
  fullname: Kumar, Rajiv
  organization: Division of Molecular Genetic Epidemiology, German Cancer Research Centre
– givenname: Maria G
  surname: Di Mauro
  fullname: Di Mauro, Maria G
  organization: Department of Immunohematology and Transfusion Medicine, Fondazione IRCCS Istituto Nazionale Tumori
– givenname: Lambertus A
  surname: Kiemeney
  fullname: Kiemeney, Lambertus A
  organization: Department of Epidemiology, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre Comprehensive Cancer Centre IKO Department of Urology, Radboud University Nijmegen Medical Centre
– givenname: Thorunn
  surname: Rafnar
  fullname: Rafnar, Thorunn
  organization: deCODE genetics
– givenname: Kvetoslava
  surname: Koppova
  fullname: Koppova, Kvetoslava
  organization: State Health Institute
– givenname: Annika
  surname: Lindblom
  fullname: Lindblom, Annika
  organization: Department of Molecular Medicine, Karolinska Institutet
– givenname: Esther
  surname: de Vries
  fullname: de Vries, Esther
  organization: Department of Public Health, Erasmus Medical Centre
– givenname: Hjördis
  surname: Bjarnason
  fullname: Bjarnason, Hjördis
  organization: deCODE genetics
– givenname: Kristleifur
  surname: Kristjansson
  fullname: Kristjansson, Kristleifur
  organization: deCODE genetics
– givenname: Gyda
  surname: Bjornsdottir
  fullname: Bjornsdottir, Gyda
  organization: deCODE genetics
– givenname: Patrick
  surname: Sulem
  fullname: Sulem, Patrick
  organization: deCODE genetics
– givenname: Valgerdur
  surname: Steinthorsdottir
  fullname: Steinthorsdottir, Valgerdur
  organization: deCODE genetics
– givenname: Dominique
  surname: Scherer
  fullname: Scherer, Dominique
  organization: Division of Molecular Genetic Epidemiology, German Cancer Research Centre
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21777715$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/19578363$$D View this record in MEDLINE/PubMed
http://kipublications.ki.se/Default.aspx?queryparsed=id:119133945$$DView record from Swedish Publication Index
BookMark eNqNkmuL1DAUhousuBf1F4gURcUPHXNya_NFWNbbwuKCt68hk6Y1a5uMSbvr_ntTps44XtAGmpDzvG-Sc85htue8M1l2F9ACEKmeuXZBAd_IDoBRXkAJ1V5aIw4FRYTvZ4cxXiAElKLqVrYPgpUV4eQge_HWXOXa9713-aUKVrkh5qppjB6sa_M4Rm1Wg13azg7X-eDzpYqqy7Xp0k8FbZ3v1e3sZqO6aO7M81H28dXLDydvirPz16cnx2eFLgUdCkUM8CVVAgTBQi8ZrTjRrCbQQMUIwqxEAnGhSspqqFmNlpxUgMqGgwBSk6OsWPvGK7Mal3IVbK_CtfTKynnrS1oZyVgJtEq8-Cu_Cr7ein4IYTqICMqS9vlam4De1Nq4Iahu12In4uxn2fpLiUVJCIFk8Hg2CP7raOIgexunvCln_BglLxkRiJb_BDESqVR4cnzwC3jhx-BSxiXGmPNKoOnND9dQqzojrWt8up2eHOUxRiwhGJFELf5ApVGb3urUWo1N-zuCpzuCxAzm29CqMUZ5-v7d_7Pnn3bZ-fE6-BiDaTYZBiSnzpaulamzE3j_53pssbmVE_BoBlTUqmuCctrGDYehTB9MhX0yN0UKudaEbRZ_O_LemnRqGIPZWM3h704NFbo
CODEN NGENEC
CitedBy_id crossref_primary_10_1093_hmg_ddt355
crossref_primary_10_1007_s12022_015_9408_1
crossref_primary_10_1172_jci_insight_134783
crossref_primary_10_12688_f1000research_5186_1
crossref_primary_10_1093_hmg_dds382
crossref_primary_10_1007_s10577_013_9391_7
crossref_primary_10_3389_fendo_2018_00405
crossref_primary_10_1002_jgm_3260
crossref_primary_10_1016_j_canep_2015_09_005
crossref_primary_10_3390_cancers15164160
crossref_primary_10_1016_j_jdermsci_2011_07_003
crossref_primary_10_1152_physrev_00058_2009
crossref_primary_10_18632_oncotarget_11041
crossref_primary_10_1111_bjd_17917
crossref_primary_10_1016_j_ejmhg_2012_08_001
crossref_primary_10_1371_journal_pone_0055712
crossref_primary_10_1038_ng_493
crossref_primary_10_1093_hmg_ddr287
crossref_primary_10_1172_JCI79048
crossref_primary_10_1182_blood_2009_09_240440
crossref_primary_10_1038_hdy_2011_55
crossref_primary_10_2217_epi_2016_0179
crossref_primary_10_1016_j_bbcan_2012_03_011
crossref_primary_10_1038_ng_2843
crossref_primary_10_1111_pcmr_12032
crossref_primary_10_1016_j_cca_2015_02_046
crossref_primary_10_1038_srep26037
crossref_primary_10_1371_journal_pone_0052598
crossref_primary_10_1016_j_biopha_2017_05_122
crossref_primary_10_1111_exd_14189
crossref_primary_10_3389_fgene_2020_527484
crossref_primary_10_1038_onc_2010_15
crossref_primary_10_1111_j_1440_0960_2009_00579_x
crossref_primary_10_1371_journal_pone_0120491
crossref_primary_10_1093_ije_dyab042
crossref_primary_10_1158_0008_5472_CAN_10_1818
crossref_primary_10_1038_ng_2635
crossref_primary_10_1038_ng_926
crossref_primary_10_5858_arpa_2017_0222_RA
crossref_primary_10_1158_1055_9965_EPI_10_0281
crossref_primary_10_3390_ijms21207559
crossref_primary_10_1093_carcin_bgq179
crossref_primary_10_1007_s00439_014_1515_4
crossref_primary_10_1146_annurev_pathol_012513_104703
crossref_primary_10_18632_oncotarget_8744
crossref_primary_10_1016_j_mrrev_2016_08_004
crossref_primary_10_1017_S146239941000147X
crossref_primary_10_1007_s00439_011_1030_9
crossref_primary_10_1016_j_it_2022_03_003
crossref_primary_10_1371_journal_pone_0084277
crossref_primary_10_3892_ijo_2012_1725
crossref_primary_10_1016_j_jaad_2019_04_044
crossref_primary_10_1111_ggi_12346
crossref_primary_10_1002_ajmg_a_35884
crossref_primary_10_1096_fj_10_172452
crossref_primary_10_1016_j_jdermsci_2012_02_017
crossref_primary_10_1158_1055_9965_EPI_11_0523
crossref_primary_10_1158_1055_9965_EPI_14_0129
crossref_primary_10_1093_carcin_bgt259
crossref_primary_10_1158_1055_9965_EPI_11_0867
crossref_primary_10_1093_hmg_ddt671
crossref_primary_10_1111_j_1474_9726_2011_00687_x
crossref_primary_10_1177_1203475415586664
crossref_primary_10_1186_1471_2407_13_325
crossref_primary_10_1016_j_gene_2012_11_067
crossref_primary_10_1093_jnci_djs222
crossref_primary_10_1371_journal_pone_0075807
crossref_primary_10_3390_ijms140918790
crossref_primary_10_1016_j_ejca_2014_09_017
crossref_primary_10_1038_ng_586
crossref_primary_10_1038_ng_585
crossref_primary_10_1158_1078_0432_CCR_12_0191
crossref_primary_10_1016_j_cellsig_2013_02_006
crossref_primary_10_1016_j_suc_2015_05_011
crossref_primary_10_1038_onc_2010_456
crossref_primary_10_1007_s40471_015_0049_1
crossref_primary_10_1200_JCO_2009_25_7816
crossref_primary_10_1111_j_1365_2133_2012_11075_x
crossref_primary_10_1093_jnci_djq173
crossref_primary_10_3390_cancers5041655
crossref_primary_10_1093_aje_kwq457
crossref_primary_10_3390_cancers11101524
crossref_primary_10_7314_APJCP_2014_15_1_123
crossref_primary_10_1111_1346_8138_12432
crossref_primary_10_1007_s00439_011_1107_5
crossref_primary_10_1093_carcin_bgr056
crossref_primary_10_1093_bmb_ldq038
crossref_primary_10_1371_journal_pone_0050650
crossref_primary_10_1007_s00403_012_1275_8
crossref_primary_10_1093_carcin_bgu203
crossref_primary_10_1242_dmm_000414
crossref_primary_10_1038_s41598_022_17443_1
crossref_primary_10_1093_hmg_ddv076
crossref_primary_10_1007_s00441_014_2105_4
crossref_primary_10_1016_j_recesp_2011_01_010
crossref_primary_10_3390_ijms14011278
crossref_primary_10_1371_journal_pone_0036116
crossref_primary_10_3389_fcvm_2020_00091
crossref_primary_10_1038_ng_687
crossref_primary_10_1038_ncomms12048
crossref_primary_10_1093_hmg_ddv622
crossref_primary_10_1158_1940_6207_CAPR_11_0063
crossref_primary_10_1016_j_hoc_2010_06_009
crossref_primary_10_4161_rna_19985
crossref_primary_10_1111_ejh_12588
crossref_primary_10_1111_j_1752_4571_2010_00156_x
crossref_primary_10_1038_s42003_023_05753_7
crossref_primary_10_1016_j_tig_2009_12_008
crossref_primary_10_1111_j_1365_2605_2011_01162_x
crossref_primary_10_1136_jnnp_2012_304045
crossref_primary_10_1016_j_ceb_2012_10_018
crossref_primary_10_1186_s40246_019_0240_4
crossref_primary_10_3390_ijms222212446
crossref_primary_10_1016_j_mrrev_2010_06_002
crossref_primary_10_1038_jid_2012_4
crossref_primary_10_1038_s41467_020_14594_5
crossref_primary_10_1038_jid_2015_62
crossref_primary_10_18632_oncotarget_24719
crossref_primary_10_1038_jhg_2010_19
crossref_primary_10_1111_j_1600_0625_2010_01139_x
crossref_primary_10_1093_carcin_bgr197
crossref_primary_10_1590_abd1806_4841_20176544
crossref_primary_10_1007_s12170_009_0063_2
crossref_primary_10_1097_COC_0b013e31820dbf28
crossref_primary_10_1016_j_ajhg_2012_09_009
crossref_primary_10_1038_jid_2012_75
crossref_primary_10_1089_dna_2019_4744
crossref_primary_10_1371_journal_pone_0022760
crossref_primary_10_1093_jnci_djr219
crossref_primary_10_1007_s10238_014_0316_3
crossref_primary_10_2217_fon_15_246
crossref_primary_10_1007_s00439_012_1232_9
crossref_primary_10_1016_j_jid_2016_03_011
crossref_primary_10_2217_pme_11_15
crossref_primary_10_1007_s12032_022_01789_7
crossref_primary_10_1038_ng_665
crossref_primary_10_1016_S0151_9638_09_73385_X
crossref_primary_10_1038_ejhg_2014_167
crossref_primary_10_1007_s10549_011_1927_y
crossref_primary_10_1002_ijc_29590
crossref_primary_10_1038_srep17369
crossref_primary_10_1111_bjd_13283
crossref_primary_10_1016_j_thromres_2011_11_014
crossref_primary_10_1038_ng_2566
crossref_primary_10_1158_0008_5472_CAN_15_2980
crossref_primary_10_1586_erm_10_64
crossref_primary_10_1111_j_1755_148X_2012_00981_x
crossref_primary_10_1038_nature08625
crossref_primary_10_1146_annurev_genom_091212_153429
crossref_primary_10_1158_0008_5472_CAN_11_1988
crossref_primary_10_1093_ilar_53_3_4_341
crossref_primary_10_18632_oncotarget_6397
crossref_primary_10_3892_ijo_2015_2943
crossref_primary_10_1016_j_ceb_2014_12_008
crossref_primary_10_1101_cshperspect_a022046
crossref_primary_10_1038_jid_2011_450
crossref_primary_10_1053_j_seminoncol_2012_01_011
crossref_primary_10_1016_j_ihj_2019_04_005
crossref_primary_10_1056_NEJMra0903373
crossref_primary_10_1016_j_gdata_2016_08_017
crossref_primary_10_7314_APJCP_2014_15_17_7443
crossref_primary_10_1038_ng_522
crossref_primary_10_1002_biof_1612
crossref_primary_10_1038_ng_3685
crossref_primary_10_1111_j_1365_2613_2012_00830_x
crossref_primary_10_1111_andr_304
crossref_primary_10_1038_jid_2011_322
crossref_primary_10_1111_pcmr_12459
crossref_primary_10_1038_ncomms7825
crossref_primary_10_1016_j_hoc_2015_04_009
crossref_primary_10_3390_cancers12113220
crossref_primary_10_1111_j_1346_8138_2012_01559_x
crossref_primary_10_1038_srep44548
crossref_primary_10_3390_ijms161023651
crossref_primary_10_1038_ng_871
crossref_primary_10_3390_cells8050497
crossref_primary_10_1093_bfgp_elr008
crossref_primary_10_1371_journal_pgen_1001016
crossref_primary_10_1371_journal_pone_0052535
crossref_primary_10_1016_j_jid_2016_03_047
crossref_primary_10_2217_mmt_15_12
crossref_primary_10_1007_s10549_018_4814_y
crossref_primary_10_1093_jnci_djr416
crossref_primary_10_1093_hmg_ddu363
crossref_primary_10_1016_j_ejca_2010_04_024
crossref_primary_10_1111_j_1365_2605_2011_01156_x
crossref_primary_10_1158_1055_9965_EPI_15_0805
crossref_primary_10_1016_j_oraloncology_2019_09_019
crossref_primary_10_1136_gutjnl_2020_321534
crossref_primary_10_1177_0146645315595585
crossref_primary_10_1002_mc_21872
crossref_primary_10_1097_MPA_0b013e318264cea5
crossref_primary_10_18632_oncotarget_6747
crossref_primary_10_18632_oncotarget_9212
crossref_primary_10_1186_1479_7364_4_4_263
crossref_primary_10_18632_oncotarget_10935
crossref_primary_10_1093_hmg_ddt142
crossref_primary_10_1016_j_urology_2011_05_035
crossref_primary_10_1016_j_rec_2011_01_011
crossref_primary_10_1158_0008_5472_CAN_13_3176
crossref_primary_10_1242_dev_145441
crossref_primary_10_1038_ng_612
crossref_primary_10_1590_S0365_05962011000200013
crossref_primary_10_1002_ijc_27417
crossref_primary_10_5858_arpa_2013_0157_RA
crossref_primary_10_1016_S0151_9638_09_73382_4
crossref_primary_10_1093_carcin_bgw107
crossref_primary_10_1186_s13046_022_02562_4
crossref_primary_10_1038_ng_3094
crossref_primary_10_1371_journal_pgen_1003652
crossref_primary_10_1111_j_1365_2362_2010_02454_x
crossref_primary_10_1038_ng_609
crossref_primary_10_1111_cas_13130
crossref_primary_10_1186_1755_8794_4_63
crossref_primary_10_1161_ATVBAHA_109_196832
crossref_primary_10_1016_j_gde_2010_03_013
crossref_primary_10_1155_2014_925716
crossref_primary_10_1002_mc_22626
crossref_primary_10_1038_jid_2013_460
crossref_primary_10_1038_ng_607
crossref_primary_10_5812_ijcm_11176
crossref_primary_10_1016_j_ejca_2012_03_006
crossref_primary_10_1038_ncomms15034
crossref_primary_10_1038_nrc_2017_82
crossref_primary_10_1111_j_1365_2133_2011_10238_x
crossref_primary_10_1161_ATVBAHA_111_232678
crossref_primary_10_18632_oncotarget_22268
crossref_primary_10_1007_s00439_011_1055_0
crossref_primary_10_1093_hmg_ddv101
crossref_primary_10_1111_j_1755_148X_2010_00730_x
crossref_primary_10_1111_jcmm_17966
crossref_primary_10_1111_j_1600_0560_2010_01557_x
crossref_primary_10_1038_jid_2011_402
crossref_primary_10_1186_s12863_019_0765_5
crossref_primary_10_3390_cancers13153870
crossref_primary_10_1016_j_jdermsci_2015_08_003
crossref_primary_10_1016_j_jid_2016_01_013
crossref_primary_10_1038_jid_2015_184
crossref_primary_10_1038_s42003_020_01461_8
crossref_primary_10_1016_j_biochi_2011_07_031
Cites_doi 10.1007/s00418-008-0435-6
10.1038/ng.160
10.1371/journal.pgen.0030065
10.1038/ng.296
10.1038/ng.234
10.1016/j.yexcr.2007.03.029
10.1038/ng.161
10.1111/j.1365-2133.2008.08682.x
10.1038/ng.2007.13
10.1002/sim.1186
10.1073/pnas.95.14.8141
10.1158/0008-5472.CAN-06-2004
10.1002/humu.20823
10.1073/pnas.90.15.7414
10.1038/ng.216
10.1038/nrc2503
10.1002/humu.20143
10.1002/humu.20652
10.1126/science.1142358
10.1038/jid.2008.238
10.1158/1055-9965.EPI-07-0152
10.1016/j.cell.2006.10.003
10.1038/ng2043
10.1002/humu.20804
10.1126/science.1142364
10.1073/pnas.0707628104
10.1126/science.1142842
10.1126/science.1142382
ContentType Journal Article
Copyright Springer Nature America, Inc. 2009
2009 INIST-CNRS
COPYRIGHT 2009 Nature Publishing Group
Copyright Nature Publishing Group Aug 2009
Copyright_xml – notice: Springer Nature America, Inc. 2009
– notice: 2009 INIST-CNRS
– notice: COPYRIGHT 2009 Nature Publishing Group
– notice: Copyright Nature Publishing Group Aug 2009
DBID IQODW
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
IOV
ISR
3V.
7QL
7QP
7QR
7SS
7T7
7TK
7TM
7U9
7X7
7XB
88A
88E
8AO
8C1
8FD
8FE
8FH
8FI
8FJ
8FK
8G5
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
C1K
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
GUQSH
H94
HCIFZ
K9.
LK8
M0S
M1P
M2O
M7N
M7P
MBDVC
P64
PQEST
PQQKQ
PQUKI
Q9U
RC3
7X8
5PM
ADTPV
AOWAS
D8T
ZZAVC
DOI 10.1038/ng.412
DatabaseName Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Gale In Context: Opposing Viewpoints
Gale In Context: Science
ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
Calcium & Calcified Tissue Abstracts
Chemoreception Abstracts
Entomology Abstracts (Full archive)
Industrial and Applied Microbiology Abstracts (Microbiology A)
Neurosciences Abstracts
Nucleic Acids Abstracts
Virology and AIDS Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Biology Database (Alumni Edition)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
Public Health Database
Technology Research Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
Research Library (Alumni Edition)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central Korea
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
Research Library Prep
AIDS and Cancer Research Abstracts
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Biological Science Collection
Health & Medical Collection (Alumni Edition)
Medical Database
Research Library
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Research Library (Corporate)
Biotechnology and BioEngineering Abstracts
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central Basic
Genetics Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
SwePub
SwePub Articles
SWEPUB Freely available online
SwePub Articles full text
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Research Library Prep
ProQuest Central Student
Technology Research Database
ProQuest Central Essentials
Nucleic Acids Abstracts
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
Research Library (Alumni Edition)
ProQuest Natural Science Collection
ProQuest Pharma Collection
Environmental Sciences and Pollution Management
ProQuest Biology Journals (Alumni Edition)
ProQuest Central
Genetics Abstracts
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Collection
AIDS and Cancer Research Abstracts
ProQuest Research Library
Chemoreception Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
ProQuest Medical Library (Alumni)
ProQuest Public Health
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Entomology Abstracts
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
Engineering Research Database
ProQuest One Academic
Calcium & Calcified Tissue Abstracts
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList
Research Library Prep

MEDLINE
Genetics Abstracts
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
Agriculture
EISSN 1546-1718
EndPage 914
ExternalDocumentID oai_swepub_ki_se_557148
oai_prod_swepub_kib_ki_se_119133945
1827326761
A205908203
10_1038_ng_412
19578363
21777715
ng.412
Genre Research Support, Non-U.S. Gov't
Journal Article
Research Support, N.I.H., Extramural
GeographicLocations Sweden
Spain
GeographicLocations_xml – name: Spain
– name: Sweden
GrantInformation_xml – fundername: NCI NIH HHS
  grantid: R01CA57494
– fundername: PHS HHS
  grantid: T32E007155
– fundername: NIEHS NIH HHS
  grantid: T32 ES007155
– fundername: NCI NIH HHS
  grantid: R01 CA057494-16
– fundername: NCI NIH HHS
  grantid: R01 CA057494
– fundername: NCI NIH HHS
  grantid: R01 CA082354
– fundername: NCI NIH HHS
  grantid: R01CA082354
GroupedDBID -
08R
123
1AW
29M
39C
3O-
3V.
4.4
53G
55
5BI
5M7
5RE
5S5
70F
7X7
85S
88A
88E
8AO
8C1
8FE
8FH
8FI
8FJ
8G5
8R4
8R5
AADWK
AAEEF
AALRV
AAPBV
AAYJO
AAYOK
AAZLF
ABAWZ
ABDBF
ABEFU
ABFLS
ABGIJ
ABOCM
ABPTK
ABUWG
ACGFS
ACIWK
ACNCT
ACPRK
ADBBV
ADBIT
ADQMX
AEDAW
AENEX
AETEA
AFFNX
AFKRA
AFRAH
AFSHS
AGCDD
AGEZK
AGHTU
AHBCP
AHGBK
AHMBA
AHSBF
ALFFA
ALMA_UNASSIGNED_HOLDINGS
ARMCB
ASPBG
AVWKF
AXYYD
AZFZN
AZQEC
B0M
BBAFP
BBNVY
BENPR
BHPHI
BKKNO
BPHCQ
BVXVI
CS3
DB5
DU5
DWQXO
DZ
EAD
EAP
EBC
EBD
EBS
EE.
EJD
EMB
EMK
EPL
ESX
EXGXG
F5P
FEDTE
FQGFK
FSGXE
FYUFA
G8K
GJ
GNUQQ
GUQSH
GX1
HCIFZ
HVGLF
HZ
IAO
IH2
IHR
INH
INR
IOV
IPNFZ
ISR
ITC
K78
KM
L7B
LK8
M0L
M1P
M2O
M7P
MVM
N9A
NNMJJ
OHM
P2P
PADUT
PQEST
PQQKQ
PQUKI
PRINS
PROAC
PSQYO
Q2X
RIG
RNS
RNT
RNTTT
RVV
SHXYY
SIXXV
SJN
SNYQT
SV3
TAOOD
TBHMF
TDRGL
TN5
TSG
TUS
VQA
X
X7M
XIP
XJT
Y6R
YHZ
ZA5
ZGI
ZXP
ZY4
---
-DZ
-~X
.55
.GJ
0R~
2FS
36B
AAHBH
AARCD
ABCQX
ABJNI
ABLJU
ABTAH
ABVXF
ACGFO
ACMJI
ADFRT
AFBBN
AGAYW
AHOSX
AIBTJ
ALIPV
AMTXH
CCPQU
EMOBN
HMCUK
HZ~
LGEZI
LOTEE
NADUK
NXXTH
ODYON
UKHRP
XOL
~8M
~KM
AADEA
AAEXX
AAJMP
AAUGY
ABEEJ
ACBMV
ACBRV
ACBYP
ACIGE
ACTTH
ACVWB
ADMDM
ADZGE
AEFTE
AGGBP
AJDOV
IQODW
NYICJ
AAYZH
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
ACBWK
CITATION
7QL
7QP
7QR
7SS
7T7
7TK
7TM
7U9
7XB
8FD
8FK
C1K
FR3
H94
K9.
M7N
MBDVC
P64
Q9U
RC3
7X8
5PM
ABDPE
ADTPV
AOWAS
D8T
ZZAVC
ID FETCH-LOGICAL-c794t-a3e16b4a919329cb54863c5d31f1853025709069a745d1d5d0b638107f61913d3
IEDL.DBID 7X7
ISSN 1061-4036
1546-1718
IngestDate Wed Nov 27 03:22:12 EST 2024
Wed Oct 30 04:58:55 EDT 2024
Tue Sep 17 21:15:03 EDT 2024
Fri Oct 25 03:51:49 EDT 2024
Fri Oct 25 22:15:32 EDT 2024
Tue Nov 19 05:02:05 EST 2024
Tue Nov 19 21:41:38 EST 2024
Wed Nov 13 00:18:10 EST 2024
Sat Sep 28 21:00:37 EDT 2024
Sat Sep 28 21:39:48 EDT 2024
Thu Nov 28 02:43:21 EST 2024
Tue Oct 15 23:38:44 EDT 2024
Sun Oct 22 16:05:38 EDT 2023
Fri Oct 11 20:46:14 EDT 2024
Tue Jun 15 14:01:01 EDT 2021
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 8
Keywords Variant
Skin disease
Basal cell carcinoma
Malignant tumor
Cancer
Language English
License CC BY 4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c794t-a3e16b4a919329cb54863c5d31f1853025709069a745d1d5d0b638107f61913d3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
OpenAccessLink http://kipublications.ki.se/Default.aspx?queryparsed=id:119133945
PMID 19578363
PQID 222668908
PQPubID 33429
PageCount 6
ParticipantIDs swepub_primary_oai_swepub_ki_se_557148
swepub_primary_oai_prod_swepub_kib_ki_se_119133945
pubmedcentral_primary_oai_pubmedcentral_nih_gov_2973331
proquest_miscellaneous_67539047
proquest_miscellaneous_20936321
proquest_journals_222668908
gale_infotracmisc_A205908203
gale_infotracacademiconefile_A205908203
gale_incontextgauss_ISR_A205908203
gale_incontextgauss_IOV_A205908203
crossref_primary_10_1038_ng_412
pubmed_primary_19578363
pascalfrancis_primary_21777715
springer_journals_10_1038_ng_412
nature_primary_ng_412
ProviderPackageCode AEDAW
AAZLF
AADWK
AAYJO
70F
ADQMX
EE.
RNTTT
RVV
ABGIJ
DB5
RNT
AHGBK
PublicationCentury 2000
PublicationDate 2009-08-01
PublicationDateYYYYMMDD 2009-08-01
PublicationDate_xml – month: 08
  year: 2009
  text: 2009-08-01
  day: 01
PublicationDecade 2000
PublicationPlace New York
PublicationPlace_xml – name: New York
– name: New York, NY
– name: United States
PublicationTitle Nature genetics
PublicationTitleAbbrev Nat Genet
PublicationTitleAlternate Nat Genet
PublicationYear 2009
Publisher Nature Publishing Group US
Nature Publishing Group
Publisher_xml – name: Nature Publishing Group US
– name: Nature Publishing Group
References Kowalewski, C. (b12) 2007; 20
Zeggini, E. (b20) 2007; 316
Fernandez, L.P. (b6) 2008; 29
Rafnar, T. (b4) 2009; 41
Higgins, J.P., Thompson, S.G. (b29) 2002; 21
Uitto, J., Richard, G., McGrath, J.A. (b10) 2007; 313
Bataille, V. (b28) 2007; 16
Kong, A. (b24) 2008; 40
Steinthorsdottir, V. (b21) 2007; 39
Moll, R., Divo, M., Langbein, L. (b7) 2008; 129
Sulem, P. (b8) 2008; 40
Sulem, P. (b9) 2007; 39
Epstein, E.H. (b2) 2008; 8
Fabbri, M. (b25) 2007; 104
Stacey, S.N. (b1) 2008; 40
Kim, W.Y., Sharpless, N.E. (b14) 2006; 127
Scott, L.J. (b19) 2007; 316
Guedj, M. (b5) 2008; 29
Parker-Katiraee, L. (b23) 2007; 3
Lin, J., Hocker, T.L., Singh, M., Tsao, H. (b16) 2008; 159
Han, J. (b27) 2008; 129
Chan, Y.M., Yu, Q.C., Fine, J.D., Fuchs, E. (b11) 1993; 90
Gudbjartsson, D.F. (b3) 2008; 40
Szeverenyi, I. (b30) 2008; 29
Shurman, D. (b13) 2006; 16
Pasmant, E. (b15) 2007; 67
Saxena, R. (b18) 2007; 316
Graf, J., Hodgson, R., van Daal, A. (b26) 2005; 25
Mishmar, D. (b22) 1998; 95
Helgadottir, A. (b17) 2007; 316
Moll, Divo, Langbein (CR7) 2008; 129
Kong (CR24) 2008; 40
Zeggini (CR20) 2007; 316
Parker-Katiraee (CR23) 2007; 3
Gudbjartsson (CR3) 2008; 40
Sulem (CR8) 2008; 40
Chan, Yu, Fine, Fuchs (CR11) 1993; 90
Higgins, Thompson (CR29) 2002; 21
Shurman (CR13) 2006; 16
Saxena (CR18) 2007; 316
Mishmar (CR22) 1998; 95
Kim, Sharpless (CR14) 2006; 127
Fabbri (CR25) 2007; 104
Sulem (CR9) 2007; 39
Epstein (CR2) 2008; 8
Uitto, Richard, McGrath (CR10) 2007; 313
Scott (CR19) 2007; 316
Lin, Hocker, Singh, Tsao (CR16) 2008; 159
Fernandez (CR6) 2008; 29
Helgadottir (CR17) 2007; 316
Guedj (CR5) 2008; 29
Han (CR27) 2008; 129
Stacey (CR1) 2008; 40
Rafnar (CR4) 2009; 41
Graf, Hodgson, van Daal (CR26) 2005; 25
Szeverenyi (CR30) 2008; 29
Kowalewski (CR12) 2007; 20
Pasmant (CR15) 2007; 67
Bataille (CR28) 2007; 16
Steinthorsdottir (CR21) 2007; 39
17890317 - Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15805-10
17463248 - Science. 2007 Jun 1;316(5829):1341-5
7688477 - Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7414-8
18488027 - Nat Genet. 2008 Jul;40(7):886-91
17480121 - PLoS Genet. 2007 May 4;3(5):e65
19151717 - Nat Genet. 2009 Feb;41(2):221-7
17055429 - Cell. 2006 Oct 20;127(2):265-75
19165921 - Nat Genet. 2008 Sep;40(9):1068-75
16581562 - Eur J Dermatol. 2006 Mar-Apr;16(2):132-5
18488028 - Nat Genet. 2008 Jul;40(7):835-7
17463249 - Science. 2007 Jun 1;316(5829):1336-41
18563784 - Hum Mutat. 2008 Sep;29(9):1161-7
17549391 - Int J Mol Med. 2007 Jul;20(1):75-8
17460697 - Nat Genet. 2007 Jun;39(6):770-5
18668136 - J Invest Dermatol. 2009 Feb;129(2):415-21
17478679 - Science. 2007 Jun 8;316(5830):1491-3
9653154 - Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8141-6
15714523 - Hum Mutat. 2005 Mar;25(3):278-84
17952075 - Nat Genet. 2007 Dec;39(12):1443-52
18849993 - Nat Genet. 2008 Nov;40(11):1313-8
18813320 - Nat Rev Cancer. 2008 Oct;8(10):743-54
17463246 - Science. 2007 Jun 1;316(5829):1331-6
17531221 - Exp Cell Res. 2007 Jun 10;313(10):1995-2009
18683857 - Hum Mutat. 2008 Sep;29(9):1154-60
17440112 - Cancer Res. 2007 Apr 15;67(8):3963-9
18547303 - Br J Dermatol. 2008 Aug;159(2):286-91
18461349 - Histochem Cell Biol. 2008 Jun;129(6):705-33
17627017 - Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1499-502
V Bataille (BFng412_CR28) 2007; 16
J Uitto (BFng412_CR10) 2007; 313
J Graf (BFng412_CR26) 2005; 25
R Saxena (BFng412_CR18) 2007; 316
A Helgadottir (BFng412_CR17) 2007; 316
J Lin (BFng412_CR16) 2008; 159
R Moll (BFng412_CR7) 2008; 129
P Sulem (BFng412_CR8) 2008; 40
LP Fernandez (BFng412_CR6) 2008; 29
C Kowalewski (BFng412_CR12) 2007; 20
YM Chan (BFng412_CR11) 1993; 90
A Kong (BFng412_CR24) 2008; 40
J Han (BFng412_CR27) 2008; 129
SN Stacey (BFng412_CR1) 2008; 40
V Steinthorsdottir (BFng412_CR21) 2007; 39
T Rafnar (BFng412_CR4) 2009; 41
E Pasmant (BFng412_CR15) 2007; 67
L Parker-Katiraee (BFng412_CR23) 2007; 3
I Szeverenyi (BFng412_CR30) 2008; 29
DF Gudbjartsson (BFng412_CR3) 2008; 40
M Guedj (BFng412_CR5) 2008; 29
LJ Scott (BFng412_CR19) 2007; 316
D Shurman (BFng412_CR13) 2006; 16
EH Epstein (BFng412_CR2) 2008; 8
D Mishmar (BFng412_CR22) 1998; 95
P Sulem (BFng412_CR9) 2007; 39
JP Higgins (BFng412_CR29) 2002; 21
E Zeggini (BFng412_CR20) 2007; 316
M Fabbri (BFng412_CR25) 2007; 104
WY Kim (BFng412_CR14) 2006; 127
References_xml – volume: 127
  start-page: 265
  year: 2006
  end-page: 275
  ident: b14
  publication-title: Cell
  contributor:
    fullname: Sharpless, N.E.
– volume: 95
  start-page: 8141
  year: 1998
  end-page: 8146
  ident: b22
  publication-title: Proc. Natl. Acad. Sci. USA
  contributor:
    fullname: Mishmar, D.
– volume: 90
  start-page: 7414
  year: 1993
  end-page: 7418
  ident: b11
  publication-title: Proc. Natl. Acad. Sci. USA
  contributor:
    fullname: Fuchs, E.
– volume: 40
  start-page: 886
  year: 2008
  end-page: 891
  ident: b3
  publication-title: Nat. Genet.
  contributor:
    fullname: Gudbjartsson, D.F.
– volume: 39
  start-page: 770
  year: 2007
  end-page: 775
  ident: b21
  publication-title: Nat. Genet.
  contributor:
    fullname: Steinthorsdottir, V.
– volume: 29
  start-page: 351
  year: 2008
  end-page: 360
  ident: b30
  publication-title: Hum. Mutat.
  contributor:
    fullname: Szeverenyi, I.
– volume: 40
  start-page: 835
  year: 2008
  end-page: 837
  ident: b8
  publication-title: Nat. Genet.
  contributor:
    fullname: Sulem, P.
– volume: 16
  start-page: 132
  year: 2006
  end-page: 135
  ident: b13
  publication-title: Eur. J. Dermatol.
  contributor:
    fullname: Shurman, D.
– volume: 41
  start-page: 221
  year: 2009
  end-page: 227
  ident: b4
  publication-title: Nat. Genet.
  contributor:
    fullname: Rafnar, T.
– volume: 40
  start-page: 1068
  year: 2008
  end-page: 1075
  ident: b24
  publication-title: Nat. Genet.
  contributor:
    fullname: Kong, A.
– volume: 316
  start-page: 1491
  year: 2007
  end-page: 1493
  ident: b17
  publication-title: Science
  contributor:
    fullname: Helgadottir, A.
– volume: 29
  start-page: 1154
  year: 2008
  end-page: 1160
  ident: b5
  publication-title: Hum. Mutat.
  contributor:
    fullname: Guedj, M.
– volume: 39
  start-page: 1443
  year: 2007
  end-page: 1452
  ident: b9
  publication-title: Nat. Genet.
  contributor:
    fullname: Sulem, P.
– volume: 67
  start-page: 3963
  year: 2007
  end-page: 3969
  ident: b15
  publication-title: Cancer Res.
  contributor:
    fullname: Pasmant, E.
– volume: 129
  start-page: 415
  year: 2008
  end-page: 421
  ident: b27
  publication-title: J. Invest. Dermatol.
  contributor:
    fullname: Han, J.
– volume: 159
  start-page: 286
  year: 2008
  end-page: 291
  ident: b16
  publication-title: Br. J. Dermatol.
  contributor:
    fullname: Tsao, H.
– volume: 104
  start-page: 15805
  year: 2007
  end-page: 15810
  ident: b25
  publication-title: Proc. Natl. Acad. Sci. USA
  contributor:
    fullname: Fabbri, M.
– volume: 20
  start-page: 75
  year: 2007
  end-page: 78
  ident: b12
  publication-title: Int. J. Mol. Med.
  contributor:
    fullname: Kowalewski, C.
– volume: 29
  start-page: 1161
  year: 2008
  end-page: 1167
  ident: b6
  publication-title: Hum. Mutat.
  contributor:
    fullname: Fernandez, L.P.
– volume: 16
  start-page: 1499
  year: 2007
  end-page: 1502
  ident: b28
  publication-title: Cancer Epidemiol. Biomarkers Prev.
  contributor:
    fullname: Bataille, V.
– volume: 25
  start-page: 278
  year: 2005
  end-page: 284
  ident: b26
  publication-title: Hum. Mutat.
  contributor:
    fullname: van Daal, A.
– volume: 313
  start-page: 1995
  year: 2007
  end-page: 2009
  ident: b10
  publication-title: Exp. Cell Res.
  contributor:
    fullname: McGrath, J.A.
– volume: 40
  start-page: 1313
  year: 2008
  end-page: 1318
  ident: b1
  publication-title: Nat. Genet.
  contributor:
    fullname: Stacey, S.N.
– volume: 129
  start-page: 705
  year: 2008
  end-page: 733
  ident: b7
  publication-title: Histochem. Cell Biol.
  contributor:
    fullname: Langbein, L.
– volume: 316
  start-page: 1336
  year: 2007
  end-page: 1341
  ident: b20
  publication-title: Science
  contributor:
    fullname: Zeggini, E.
– volume: 316
  start-page: 1341
  year: 2007
  end-page: 1345
  ident: b19
  publication-title: Science
  contributor:
    fullname: Scott, L.J.
– volume: 21
  start-page: 1539
  year: 2002
  end-page: 1558
  ident: b29
  publication-title: Stat. Med.
  contributor:
    fullname: Thompson, S.G.
– volume: 8
  start-page: 743
  year: 2008
  end-page: 754
  ident: b2
  publication-title: Nat. Rev. Cancer
  contributor:
    fullname: Epstein, E.H.
– volume: 316
  start-page: 1331
  year: 2007
  end-page: 1336
  ident: b18
  publication-title: Science
  contributor:
    fullname: Saxena, R.
– volume: 3
  start-page: e65
  year: 2007
  ident: b23
  publication-title: PLoS Genet.
  contributor:
    fullname: Parker-Katiraee, L.
– volume: 129
  start-page: 705
  year: 2008
  end-page: 733
  ident: CR7
  article-title: The human keratins: biology and pathology
  publication-title: Histochem. Cell Biol.
  doi: 10.1007/s00418-008-0435-6
  contributor:
    fullname: Langbein
– volume: 40
  start-page: 835
  year: 2008
  end-page: 837
  ident: CR8
  article-title: Two newly identified genetic determinants of pigmentation in Europeans
  publication-title: Nat. Genet.
  doi: 10.1038/ng.160
  contributor:
    fullname: Sulem
– volume: 16
  start-page: 132
  year: 2006
  end-page: 135
  ident: CR13
  article-title: Epidermolysis Bullosa Simplex with mottled pigmentation: mutation analysis in the first reported Hispanic pedigree with the largest single generation of affected individuals to date
  publication-title: Eur. J. Dermatol.
  contributor:
    fullname: Shurman
– volume: 3
  start-page: e65
  year: 2007
  ident: CR23
  article-title: Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.0030065
  contributor:
    fullname: Parker-Katiraee
– volume: 41
  start-page: 221
  year: 2009
  end-page: 227
  ident: CR4
  article-title: Sequence variants at the locus associate with many cancer types
  publication-title: Nat. Genet.
  doi: 10.1038/ng.296
  contributor:
    fullname: Rafnar
– volume: 40
  start-page: 1313
  year: 2008
  end-page: 1318
  ident: CR1
  article-title: Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits
  publication-title: Nat. Genet.
  doi: 10.1038/ng.234
  contributor:
    fullname: Stacey
– volume: 313
  start-page: 1995
  year: 2007
  end-page: 2009
  ident: CR10
  article-title: Diseases of epidermal keratins and their linker proteins
  publication-title: Exp. Cell Res.
  doi: 10.1016/j.yexcr.2007.03.029
  contributor:
    fullname: McGrath
– volume: 40
  start-page: 886
  year: 2008
  end-page: 891
  ident: CR3
  article-title: and pigmentation variants associate with cutaneous melanoma and basal cell carcinoma
  publication-title: Nat. Genet.
  doi: 10.1038/ng.161
  contributor:
    fullname: Gudbjartsson
– volume: 159
  start-page: 286
  year: 2008
  end-page: 291
  ident: CR16
  article-title: Genetics of melanoma predisposition
  publication-title: Br. J. Dermatol.
  doi: 10.1111/j.1365-2133.2008.08682.x
  contributor:
    fullname: Tsao
– volume: 39
  start-page: 1443
  year: 2007
  end-page: 1452
  ident: CR9
  article-title: Genetic determinants of hair, eye and skin pigmentation in Europeans
  publication-title: Nat. Genet.
  doi: 10.1038/ng.2007.13
  contributor:
    fullname: Sulem
– volume: 21
  start-page: 1539
  year: 2002
  end-page: 1558
  ident: CR29
  article-title: Quantifying heterogeneity in a meta-analysis
  publication-title: Stat. Med.
  doi: 10.1002/sim.1186
  contributor:
    fullname: Thompson
– volume: 95
  start-page: 8141
  year: 1998
  end-page: 8146
  ident: CR22
  article-title: Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.95.14.8141
  contributor:
    fullname: Mishmar
– volume: 67
  start-page: 3963
  year: 2007
  end-page: 3969
  ident: CR15
  article-title: Characterization of a germ-line deletion, including the entire locus, in a melanoma-neural system tumor family: identification of , an antisense noncoding RNA whose expression coclusters with
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-06-2004
  contributor:
    fullname: Pasmant
– volume: 29
  start-page: 1154
  year: 2008
  end-page: 1160
  ident: CR5
  article-title: Variants of the / gene are protective for melanoma in the French population
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20823
  contributor:
    fullname: Guedj
– volume: 20
  start-page: 75
  year: 2007
  end-page: 78
  ident: CR12
  article-title: A novel autosomal partially dominant mutation designated G476D in the keratin 5 gene causing epidermolysis bullosa simplex Weber-Cockayne type: a family study with a genetic twist
  publication-title: Int. J. Mol. Med.
  contributor:
    fullname: Kowalewski
– volume: 90
  start-page: 7414
  year: 1993
  end-page: 7418
  ident: CR11
  article-title: The genetic basis of Weber-Cockayne epidermolysis bullosa simplex
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.90.15.7414
  contributor:
    fullname: Fuchs
– volume: 40
  start-page: 1068
  year: 2008
  end-page: 1075
  ident: CR24
  article-title: Detection of sharing by descent, long-range phasing and haplotype imputation
  publication-title: Nat. Genet.
  doi: 10.1038/ng.216
  contributor:
    fullname: Kong
– volume: 8
  start-page: 743
  year: 2008
  end-page: 754
  ident: CR2
  article-title: Basal cell carcinomas: attack of the hedgehog
  publication-title: Nat. Rev. Cancer
  doi: 10.1038/nrc2503
  contributor:
    fullname: Epstein
– volume: 25
  start-page: 278
  year: 2005
  end-page: 284
  ident: CR26
  article-title: Single nucleotide polymorphisms in the gene are associated with normal human pigmentation variation
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20143
  contributor:
    fullname: van Daal
– volume: 29
  start-page: 351
  year: 2008
  end-page: 360
  ident: CR30
  article-title: The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20652
  contributor:
    fullname: Szeverenyi
– volume: 316
  start-page: 1331
  year: 2007
  end-page: 1336
  ident: CR18
  article-title: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
  publication-title: Science
  doi: 10.1126/science.1142358
  contributor:
    fullname: Saxena
– volume: 129
  start-page: 415
  year: 2008
  end-page: 421
  ident: CR27
  article-title: A prospective study of telomere length and the risk of skin cancer
  publication-title: J. Invest. Dermatol.
  doi: 10.1038/jid.2008.238
  contributor:
    fullname: Han
– volume: 16
  start-page: 1499
  year: 2007
  end-page: 1502
  ident: CR28
  article-title: Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo
  publication-title: Cancer Epidemiol. Biomarkers Prev.
  doi: 10.1158/1055-9965.EPI-07-0152
  contributor:
    fullname: Bataille
– volume: 127
  start-page: 265
  year: 2006
  end-page: 275
  ident: CR14
  article-title: The regulation of INK4/ARF in cancer and aging
  publication-title: Cell
  doi: 10.1016/j.cell.2006.10.003
  contributor:
    fullname: Sharpless
– volume: 39
  start-page: 770
  year: 2007
  end-page: 775
  ident: CR21
  article-title: A variant in influences insulin response and risk of type 2 diabetes
  publication-title: Nat. Genet.
  doi: 10.1038/ng2043
  contributor:
    fullname: Steinthorsdottir
– volume: 29
  start-page: 1161
  year: 2008
  end-page: 1167
  ident: CR6
  article-title: : a novel malignant melanoma-associated gene
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20804
  contributor:
    fullname: Fernandez
– volume: 316
  start-page: 1336
  year: 2007
  end-page: 1341
  ident: CR20
  article-title: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
  publication-title: Science
  doi: 10.1126/science.1142364
  contributor:
    fullname: Zeggini
– volume: 104
  start-page: 15805
  year: 2007
  end-page: 15810
  ident: CR25
  article-title: MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.0707628104
  contributor:
    fullname: Fabbri
– volume: 316
  start-page: 1491
  year: 2007
  end-page: 1493
  ident: CR17
  article-title: A common variant on chromosome 9p21 affects the risk of myocardial infarction
  publication-title: Science
  doi: 10.1126/science.1142842
  contributor:
    fullname: Helgadottir
– volume: 316
  start-page: 1341
  year: 2007
  end-page: 1345
  ident: CR19
  article-title: A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
  publication-title: Science
  doi: 10.1126/science.1142382
  contributor:
    fullname: Scott
– volume: 316
  start-page: 1491
  year: 2007
  ident: BFng412_CR17
  publication-title: Science
  doi: 10.1126/science.1142842
  contributor:
    fullname: A Helgadottir
– volume: 29
  start-page: 1154
  year: 2008
  ident: BFng412_CR5
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20823
  contributor:
    fullname: M Guedj
– volume: 39
  start-page: 1443
  year: 2007
  ident: BFng412_CR9
  publication-title: Nat. Genet.
  doi: 10.1038/ng.2007.13
  contributor:
    fullname: P Sulem
– volume: 127
  start-page: 265
  year: 2006
  ident: BFng412_CR14
  publication-title: Cell
  doi: 10.1016/j.cell.2006.10.003
  contributor:
    fullname: WY Kim
– volume: 316
  start-page: 1341
  year: 2007
  ident: BFng412_CR19
  publication-title: Science
  doi: 10.1126/science.1142382
  contributor:
    fullname: LJ Scott
– volume: 21
  start-page: 1539
  year: 2002
  ident: BFng412_CR29
  publication-title: Stat. Med.
  doi: 10.1002/sim.1186
  contributor:
    fullname: JP Higgins
– volume: 20
  start-page: 75
  year: 2007
  ident: BFng412_CR12
  publication-title: Int. J. Mol. Med.
  contributor:
    fullname: C Kowalewski
– volume: 40
  start-page: 1068
  year: 2008
  ident: BFng412_CR24
  publication-title: Nat. Genet.
  doi: 10.1038/ng.216
  contributor:
    fullname: A Kong
– volume: 29
  start-page: 1161
  year: 2008
  ident: BFng412_CR6
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20804
  contributor:
    fullname: LP Fernandez
– volume: 129
  start-page: 415
  year: 2008
  ident: BFng412_CR27
  publication-title: J. Invest. Dermatol.
  doi: 10.1038/jid.2008.238
  contributor:
    fullname: J Han
– volume: 90
  start-page: 7414
  year: 1993
  ident: BFng412_CR11
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.90.15.7414
  contributor:
    fullname: YM Chan
– volume: 316
  start-page: 1331
  year: 2007
  ident: BFng412_CR18
  publication-title: Science
  doi: 10.1126/science.1142358
  contributor:
    fullname: R Saxena
– volume: 3
  start-page: e65
  year: 2007
  ident: BFng412_CR23
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.0030065
  contributor:
    fullname: L Parker-Katiraee
– volume: 40
  start-page: 835
  year: 2008
  ident: BFng412_CR8
  publication-title: Nat. Genet.
  doi: 10.1038/ng.160
  contributor:
    fullname: P Sulem
– volume: 8
  start-page: 743
  year: 2008
  ident: BFng412_CR2
  publication-title: Nat. Rev. Cancer
  doi: 10.1038/nrc2503
  contributor:
    fullname: EH Epstein
– volume: 159
  start-page: 286
  year: 2008
  ident: BFng412_CR16
  publication-title: Br. J. Dermatol.
  doi: 10.1111/j.1365-2133.2008.08682.x
  contributor:
    fullname: J Lin
– volume: 41
  start-page: 221
  year: 2009
  ident: BFng412_CR4
  publication-title: Nat. Genet.
  doi: 10.1038/ng.296
  contributor:
    fullname: T Rafnar
– volume: 40
  start-page: 886
  year: 2008
  ident: BFng412_CR3
  publication-title: Nat. Genet.
  doi: 10.1038/ng.161
  contributor:
    fullname: DF Gudbjartsson
– volume: 129
  start-page: 705
  year: 2008
  ident: BFng412_CR7
  publication-title: Histochem. Cell Biol.
  doi: 10.1007/s00418-008-0435-6
  contributor:
    fullname: R Moll
– volume: 316
  start-page: 1336
  year: 2007
  ident: BFng412_CR20
  publication-title: Science
  doi: 10.1126/science.1142364
  contributor:
    fullname: E Zeggini
– volume: 39
  start-page: 770
  year: 2007
  ident: BFng412_CR21
  publication-title: Nat. Genet.
  doi: 10.1038/ng2043
  contributor:
    fullname: V Steinthorsdottir
– volume: 16
  start-page: 132
  year: 2006
  ident: BFng412_CR13
  publication-title: Eur. J. Dermatol.
  contributor:
    fullname: D Shurman
– volume: 67
  start-page: 3963
  year: 2007
  ident: BFng412_CR15
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-06-2004
  contributor:
    fullname: E Pasmant
– volume: 95
  start-page: 8141
  year: 1998
  ident: BFng412_CR22
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.95.14.8141
  contributor:
    fullname: D Mishmar
– volume: 16
  start-page: 1499
  year: 2007
  ident: BFng412_CR28
  publication-title: Cancer Epidemiol. Biomarkers Prev.
  doi: 10.1158/1055-9965.EPI-07-0152
  contributor:
    fullname: V Bataille
– volume: 25
  start-page: 278
  year: 2005
  ident: BFng412_CR26
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20143
  contributor:
    fullname: J Graf
– volume: 40
  start-page: 1313
  year: 2008
  ident: BFng412_CR1
  publication-title: Nat. Genet.
  doi: 10.1038/ng.234
  contributor:
    fullname: SN Stacey
– volume: 104
  start-page: 15805
  year: 2007
  ident: BFng412_CR25
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.0707628104
  contributor:
    fullname: M Fabbri
– volume: 29
  start-page: 351
  year: 2008
  ident: BFng412_CR30
  publication-title: Hum. Mutat.
  doi: 10.1002/humu.20652
  contributor:
    fullname: I Szeverenyi
– volume: 313
  start-page: 1995
  year: 2007
  ident: BFng412_CR10
  publication-title: Exp. Cell Res.
  doi: 10.1016/j.yexcr.2007.03.029
  contributor:
    fullname: J Uitto
SSID ssj0014408
Score 2.5021021
Snippet In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility...
Simon Stacey and colleagues report several new susceptibility variants for basal cell carcinoma, including coding variants in KRT5 , a variant at 9p21 near...
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC) (1), we describe here several new...
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC) 1 , we describe here several new susceptibility...
SourceID swepub
pubmedcentral
proquest
gale
crossref
pubmed
pascalfrancis
springer
nature
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 909
SubjectTerms Agriculture
Animal Genetics and Genomics
Basal cell carcinoma
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cancer
Cancer Research
Carcinoma, Basal Cell - complications
Carcinoma, Basal Cell - genetics
Carcinoma, Squamous Cell - genetics
Cells
Chromosomes, Human, Pair 7 - genetics
Chromosomes, Human, Pair 9 - genetics
Coronary Artery Disease - complications
Coronary Artery Disease - genetics
Cyclin-dependent kinases
Dermatology
Disease susceptibility
Environmental health
Fundamental and applied biological sciences. Psychology
Gene Function
Genetic aspects
Genetic Predisposition to Disease
Genetics of eukaryotes. Biological and molecular evolution
Genome-Wide Association Study
Health aspects
Human Genetics
Humans
Keratin
Keratin-5 - genetics
letter
Linkage Disequilibrium - genetics
Medical sciences
Medicin och hälsovetenskap
Melanoma
Melanoma - pathology
Membrane Proteins - genetics
Molecular Sequence Data
Multivariate analysis
Neoplasm Proteins - genetics
Pigmentation
Polymorphism, Single Nucleotide - genetics
Risk factors
Sample size
Single nucleotide polymorphisms
Skin Neoplasms - complications
Skin Neoplasms - genetics
Tumors of the skin and soft tissue. Premalignant lesions
Ultraviolet radiation
Title New common variants affecting susceptibility to basal cell carcinoma
URI http://dx.doi.org/10.1038/ng.412
https://link.springer.com/article/10.1038/ng.412
https://www.ncbi.nlm.nih.gov/pubmed/19578363
https://www.proquest.com/docview/222668908
https://search.proquest.com/docview/20936321
https://search.proquest.com/docview/67539047
https://pubmed.ncbi.nlm.nih.gov/PMC2973331
http://kipublications.ki.se/Default.aspx?queryparsed=id:119133945
Volume 41
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9MwELdgExLShPgYo2wUCyF4Covj2Imf0BibBhIDDYb6ZjmxXaaJpJAWaf89d3GSKWOjUvsQXx3nfL7z5c73I-SlK01SGiYjn0oLDgpTUS7iOEo92JrCF0Z5PCj86VgenaYfZ2LW5eY0XVplrxNbRW3rEt-R74IdkzJXcf528StC0CgMrnYIGrfJOkvA1oI4Z7PB38KwZTgJJ9FNwihlgBbi-W41f5OyZGSLOo08FNTcWJgG2OQDvsV1G9B_8yiHYOqVwqOtsTq8T-51u0y6F8TiAbnlqofkTsCdvHhE3oNqo_DY8FD0DzjLmAtDTZvZAf3SZtW0yS5t3uwFXdYUbB10hy_5aYngQ1X902yS08ODb_tHUQenEJWw6JaR4Y7JIjUK92yqLMBXkbwUljOPRjtGPDsVS2WyVFhmhY0LifW_Mg9OFuOWPyZrVV25J4QKsHEW_E9nnUwL6w3njmcutzJLnLfFhDzvGasXoWqGbqPdPNfVXAPrJ-QF8ltjCYoKc1zmZtU0-sPn73ovCUDsMb-J6OvJiOh1R-RrmIXSdOcKYKRY2mpEuTOihIVUjpo3w9wPQ-6HOh2JwtAM3hx8mJiQ7V42dKcBGj3IK_BiaMU7YlJb5eoVkMSKS56wmynAm-MqTrMJ2QqSdslNJfD8DQw6G8ngQIBlw8ct1dmPtnw4opVxDnelvbRejvrqJCVBise9gmXX3fXzM_zqxmksFMi5SoEbr67500CPtEJk4IU__S_btsndELjDXMsdsrb8vXLPYP-3LKbtKofffJ9Nyfq7g-MvJ38BSQ5eEw
link.rule.ids 230,315,782,786,887,12063,12230,21395,27931,27932,31726,31727,33273,33274,33751,33752,43317,43586,43812,73752,74021,74309
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9QwDI9gCIGEEB8DysYWIQRP3dqmSZsnNAHTDbYhwYbuLUqb5JgQ7UHvkPbfYze5Th0bJ_Xl4qau48T51Y5NyCtb66zWqYhdLgwAlFTGJU-SOHdgaypXaenwoPDRsZic5h-nfBpic7oQVrlaE_uF2rQ1fiPfBTsmRCmT8u38V4xFo9C5Gipo3CS38OAPYq9iOuAtdFv6k3ACYRJ6KX1pIVbuNrOdPM1GtiisyENCzXtz3YGYnK9vcdUG9N84ysGZeinxaG-s9h-Q-2GXSfe8WjwkN2zziNz2dSfPH5P3sLRReG14KfoHwDLGwlDdR3ZAv7Rbdn2wSx83e04XLQVbB93hR35aY_Ghpv2p18np_oeTd5M4lFOIa5h0i1gzm4oq1xL3bLKuAKsIVnPDUodGO8F6djIRUhc5N6nhJqkE5v8qHICslBn2hKw1bWOfEcrBxhnAn9ZYkVfGacYsK2xpRJFZZ6qIbK8Eq-Y-a4bqvd2sVM1Mgegj8hLlrTAFRYMxLjO97Dp18Pmb2st8IfaEXUf09cuI6E0gci2MQq3DuQLgFFNbjSg3R5QwkepR87of-4HlFatbI1UYmgHNwS_lEdlY6YYKK0CnBn0FWQyt-EQMamtsuwSSRDLBsvR6CkBzTCZ5EZGnXtMupCk5nr8BpouRDg4EmDZ83NKcfe_Th2O1MpgtEaErbb3g-vIgZV6Lx72CZVfh_x9neKnOKkwUyJjMQRqvr7hpoEdazgtA4c__K7ZtcmdycnSoDg-OP22Qu96Jh3GXm2Rt8XtpX8BecFFt9TP-L71oXpw
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9QwDI9gCISEEB8Djo2tQgieyrVNkzRPaGKcNj4GAobuLUqb5JgQ7UHvkPbfYzdpp46Nk_pycVPXceK4dvwj5JmtdFbplMcu5wYclFTGBUuSOHdga0pXaunwoPCHI35wnL-ds3koKdSGtMp-TewWatNU-I18CnaM80ImxdSFrIhP-7NXy18xAkhhoDWgaVwl1wQVDMEMxHzwvTCE6U_FcXSZMGLpYYZoMa0XL_M0G9mlsDoPxTVvLXULInMe6-Kizei_OZVDYPVcEdLOcM3ukNthxxnteRW5S67Y-h657jEoT--TfVjmIhABvFT0BxxnzIuJdJflAf1G7brtEl-6HNrTaNVEYPegO_zgH1UIRFQ3P_UmOZ69-fr6IA7QCnEFE3AVa2pTXuZa4v5NViX4LZxWzNDUoQFPENtOJlxqkTOTGmaSkmMtMOHA4UqpoQ_IRt3U9hGJGNg7A76oNZbnpXGaUkuFLQwXmXWmnJDdXrBq6StoqC7yTQtVLxSIfkKeorwVlqOocWQXet226vDjN7WXeVD2hF5G9OXziOhFIHINjEKlwxkD4BTLXI0ot0eUMKmqUfOmH_uB5Z7VnZEqDM3g2cEvZROy1euGCqtBqwbdBVkMrfhETHCrbbMGkkRSTrP0cgrw7KhMcjEhD72mnUlTMjyLA0yLkQ4OBFhCfNxSn3zvSokjchml8NSo19Yzrs8PUua1eNwrWHkV_v9xgpdqrcKigZTKHKTx_IKbBnqkZUyAR_74v2LbJTdgsqv3h0fvtshNH8_DFMxtsrH6vbZPYFu4Kne6Cf8XYmVi0w
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=New+common+variants+affecting+susceptibility+to+basal+cell+carcinoma&rft.jtitle=Nature+genetics&rft.date=2009-08-01&rft.pub=Nature+Publishing+Group&rft.issn=1061-4036&rft.volume=41&rft.issue=8&rft.spage=909&rft_id=info:doi/10.1038%2Fng.412&rft.externalDBID=ISR&rft.externalDocID=A205908203
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1061-4036&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1061-4036&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1061-4036&client=summon