Rapid Molecular Detection of Tuberculosis

• Published in: The New England journal of medicine Vol. 364; no. 2; pp. 182 - 185
• Main Author: Mohapatra, Prasanta Raghab
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 13.01.2011
• Subjects: Bacterial Proteins - genetics; Colleges & universities; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial - genetics; Humans; Medical research; Mutation; Mycobacterium tuberculosis - drug effects; Mycobacterium tuberculosis - genetics; Polymerase Chain Reaction - methods; Rifampin - pharmacology; Tuberculosis, Multidrug-Resistant - diagnosis

To the Editor: Boehme et al. (Sept. 9 issue) 1 report encouraging results on the use of an automated molecular test for Mycobacterium tuberculosis and resistance to rifampin (Xpert MTB/RIF). However, the population of patients with clinical tuberculosis who have negative cultures still poses a probl...