Genome-Wide Association Analysis in Asthma Subjects Identifies SPATS2L as a Novel Bronchodilator Response Gene - Himes, Blanca E.; Jiang, Xiaofeng; Hu, Ruoxi; Wu, Ann C.; Lasky-Su, Jessica A.; Klanderman, Barbara J.; Ziniti, John; Senter-Sylvia, Jody; Lima, John J.; Irvin, Charles G.; Peters, Stephen P.; Meyers, Deborah A.; et al. (PLoS genetics, 2012)
Keywords: Adolescent; Adrenergic beta-2 Receptor Agonists - administration & dosage; Adult; Aged; Aged, 80 and over; Airway management; Airway Obstruction - pathology; Asthma; Asthma - drug therapy; Asthma - genetics; Biology; Biomarkers, Pharmacological; Bronchi - metabolism; Bronchi - pathology; Bronchodilator Agents - administration & dosage; Child, Preschool; Clinical trials; Clinical Trials as Topic; Development and progression; Experiments; Female; Genes; Genetic aspects; Genetic polymorphisms; Genetics; Genome-Wide Association Study; Genomes; Genomics; Humans; Kinases; Male; Medicine; Middle Aged; Muscular system; Myocytes, Smooth Muscle - metabolism; Phenotype; Physiological aspects; Polymorphism, Single Nucleotide; Proteins - genetics; Smooth muscle; United States