A Randomized, Double-Blind, Placebo-Controlled Phase II Trial Investigating the Safety and Immunogenicity of Modified Vaccinia Ankara Smallpox Vaccine (MVA-BN®) in 56-80-Year-Old Subjects - Greenberg, Richard N.; Hay, Christine M.; Stapleton, Jack T.; Marbury, Thomas C.; Wagner, Eva; Kreitmeir, Eva; Röesch, Siegfried; von Krempelhuber, Alfred; Young, Philip; Nichols, Richard; Meyer, Thomas P.; Schmidt, Darja; et al. (PloS one, 2016)
Keywords: Aged, 80 and over; Analysis; Biology and Life Sciences; Body temperature; Clinical trials; Demography; Double-Blind Method; Double-blind studies; EKG; Enzyme-Linked Immunosorbent Assay; Erythema; Fatigue; Female; Headache; Health care; HIV; Human immunodeficiency virus; Humans; Immune response (humoral); Immune system; Immunogenicity; Immunological memory; Infections; Injection; Lymphocytes B; Male; Medical prognosis; Medicine and Health Sciences; Middle Aged; Myalgia; Nausea; Neutralization; Pain; Placebos; Population; Product development; Pruritus; Public health; Replicating; Replication; Research and Analysis Methods; Safety; Seroconversion; Smallpox; Smallpox Vaccine - adverse effects; Smallpox Vaccine - immunology; Smallpox vaccines; Studies; Vaccination; Vaccines; Vaccines, DNA; Vaccinia; Variola major; Viral Plaque Assay; Viral Vaccines - adverse effects; Viral Vaccines - immunology; Viruses; United States; Ankara Turkey; Iowa City Iowa; Turkey; United States--US; Germany