Accelerated Porosity Screening Using a Multichannel Colorimetric Array
Porous materials are important for many technologies, but the measurement of porosity by gas adsorption isotherms is slow, taking around one day per sample using a single‐port gas sorption analyzer, even when using a “quick” analysis method with relatively few data points. With the increased use of...
Saved in:
| Published in | Angewandte Chemie |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
21.08.2025
|
| Online Access | Get full text |
| ISSN | 0044-8249 1521-3757 |
| DOI | 10.1002/ange.202510400 |
Cover
Loading…
| Abstract | Porous materials are important for many technologies, but the measurement of porosity by gas adsorption isotherms is slow, taking around one day per sample using a single‐port gas sorption analyzer, even when using a “quick” analysis method with relatively few data points. With the increased use of automated platforms for material generation, porosity analysis is now frequently the bottleneck in the discovery of new porous materials. Here, we present a semiautomated pre‐screening strategy that uses dye adsorption to create a colorimetric array that is combined with computer vision analysis for porosity screening. By using a six‐dye multichannel array and a defined porosity threshold, our method rapidly screened 50 candidate materials that spanned molecular solids, polymers, and metal–organic frameworks. The method showed a 98–100% classification accuracy compared with gas uptake measurements. While this method is more qualitative than quantitative, it is more than 30 times faster than conventional gas sorption measurements, and it has the scope to be made much faster with greater parallelization and automation. This makes this colorimetric method suitable for pre‐screening arrays of materials to choose samples that merit more detailed conventional porosity analysis. |
|---|---|
| AbstractList | Porous materials are important for many technologies, but the measurement of porosity by gas adsorption isotherms is slow, taking around one day per sample using a single‐port gas sorption analyzer, even when using a “quick” analysis method with relatively few data points. With the increased use of automated platforms for material generation, porosity analysis is now frequently the bottleneck in the discovery of new porous materials. Here, we present a semiautomated pre‐screening strategy that uses dye adsorption to create a colorimetric array that is combined with computer vision analysis for porosity screening. By using a six‐dye multichannel array and a defined porosity threshold, our method rapidly screened 50 candidate materials that spanned molecular solids, polymers, and metal–organic frameworks. The method showed a 98–100% classification accuracy compared with gas uptake measurements. While this method is more qualitative than quantitative, it is more than 30 times faster than conventional gas sorption measurements, and it has the scope to be made much faster with greater parallelization and automation. This makes this colorimetric method suitable for pre‐screening arrays of materials to choose samples that merit more detailed conventional porosity analysis. |
| Author | Boott, Charlotte E. Cooper, Andrew I. Dutta, Biplab Qu, Hang Han, Yushu Borne, Isaiah James, Alex Little, Marc A. Clowes, Rob |
| Author_xml | – sequence: 1 givenname: Yushu orcidid: 0009-0004-1990-0196 surname: Han fullname: Han, Yushu organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 2 givenname: Isaiah surname: Borne fullname: Borne, Isaiah organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 3 givenname: Biplab surname: Dutta fullname: Dutta, Biplab organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 4 givenname: Rob orcidid: 0009-0002-4686-2119 surname: Clowes fullname: Clowes, Rob organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 5 givenname: Hang orcidid: 0000-0001-8726-3062 surname: Qu fullname: Qu, Hang organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 6 givenname: Alex surname: James fullname: James, Alex organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 7 givenname: Charlotte E. orcidid: 0000-0003-0902-030X surname: Boott fullname: Boott, Charlotte E. organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK – sequence: 8 givenname: Marc A. orcidid: 0000-0002-1994-0591 surname: Little fullname: Little, Marc A. organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK, Institute of Chemical Sciences Heriot‐Watt University Edinburgh EH14 4AS UK – sequence: 9 givenname: Andrew I. orcidid: 0000-0003-0201-1021 surname: Cooper fullname: Cooper, Andrew I. organization: Department of Chemistry and Materials Innovation Factory University of Liverpool 51 Oxford Street Liverpool L7 3NY UK |
| BookMark | eNo9kMFOhDAURRszJjKjW9f8APhaWkqXhDg6yRhNHNekLa8jBotpccHfC9G4uXd1b07Olmz86JGQWwo5BWB32p8xZ8AEBQ5wQRIqGM0KKeSGJACcZxXj6opsY_wAgJJJlZB9bS0OGPSEXfoyhjH205y-2oDoe39O3-KaOn36HqbevmvvcUibcRhD_4lT6G1ah6Dna3Lp9BDx5q935LS_PzWP2fH54dDUx8xKBZkTFI1hlHdal4p3UBlROq2VAeGws2hkIaRBy53uJAdUtFsmzgpTcadMsSP5761dQGNA134tHDrMLYV2ldCuEtp_CcUP1h1TxA |
| Cites_doi | 10.3390/ma13081869 10.1039/D4DD00334A 10.1039/D1SC04588A 10.1038/s41467-024-47070-5 10.1021/acscatal.2c02743 10.1002/anie.200390303 10.1021/acs.oprd.3c00091 10.1126/science.1230444 10.1002/anie.202104318 10.1016/j.acthis.2024.152154 10.1016/j.egypro.2011.01.161 10.1039/D0TA00219D 10.1021/ja500330a 10.1039/D3SC06206F 10.1177/24726303211047839 10.1016/j.micromeso.2017.06.001 10.1016/0143-7208(95)00067-4 10.1021/la000578m 10.1002/xrs.560 10.1021/acs.chemmater.7b00441 10.1038/s44160-024-00494-9 10.3390/molecules26175419 10.3390/molecules28196951 10.1039/c3ta12497e 10.1039/C2CS35378D 10.1615/JPorMedia.v16.i7.30 10.1126/science.aaa8075 10.1002/anie.202412045 10.1038/s41467-020-18639-7 10.1126/science.aav2211 10.1016/j.xcrp.2023.101633 10.1038/s41467-020-19926-z 10.1007/s10895-024-04001-3 10.1126/science.ads0901 10.1002/anie.201600995 10.1039/D3SC06133G 10.1021/acs.langmuir.3c00256 10.1038/s41563-021-01054-8 10.1016/j.crgsc.2021.100179 10.1002/adma.202201502 10.1002/anie.202413395 10.1002/anie.200701595 10.1002/adfm.201200591 10.1002/adma.202002780 10.1021/acs.accounts.1c00654 10.1016/j.chempr.2022.01.012 10.1039/C2CS35244C 10.1021/ja3055639 10.1021/acscombsci.5b00049 10.1039/C2CS35251F 10.3390/ma7043198 10.1021/jacsau.2c00389 10.1016/j.matpr.2023.03.716 10.1038/s41586-022-05310-y 10.1021/jacs.5b00838 |
| ContentType | Journal Article |
| DBID | AAYXX CITATION |
| DOI | 10.1002/ange.202510400 |
| DatabaseName | CrossRef |
| DatabaseTitle | CrossRef |
| DatabaseTitleList | CrossRef |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EISSN | 1521-3757 |
| ExternalDocumentID | 10_1002_ange_202510400 |
| GroupedDBID | -~X .3N .GA 05W 0R~ 10A 1L6 1OB 1OC 1ZS 33P 3SF 3WU 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 5VS 66C 6P2 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHQN AAMMB AAMNL AANLZ AAONW AAXRX AAYCA AAYXX AAZKR ABCQN ABCUV ABDBF ABEML ABIJN ABJNI ABLJU ABPVW ACAHQ ACCUC ACCZN ACGFS ACIWK ACNCT ACPOU ACPRK ACSCC ACXBN ACXQS ADBBV ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN AEFGJ AEIGN AEIMD AEUYR AEYWJ AFBPY AFFPM AFGKR AFRAH AFWVQ AGHNM AGXDD AGYGG AHBTC AIDQK AIDYY AITYG AIURR AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ATUGU AUFTA AZBYB AZVAB BAFTC BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BY8 CITATION CS3 D-E D-F DCZOG DPXWK DR2 DRFUL DRSTM EBS F00 F01 F04 F5P G-S G.N GNP GODZA H.T H.X HGLYW HHY HHZ HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LITHE LOXES LP6 LP7 LUTES LYRES MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ O66 O9- OIG P2W P2X P4D Q.N Q11 QB0 QRW R.K ROL RX1 RYL SUPJJ TN5 UB1 UPT V2E W8V W99 WBFHL WBKPD WIH WIK WJL WOHZO WQJ WXSBR WYISQ XG1 XV2 Y6R ZZTAW ~IA ~WT |
| ID | FETCH-LOGICAL-c790-f51ebb214daa694d08b56faa9b05fedceb7357bec4fad740e91d51efc5b84f9b3 |
| ISSN | 0044-8249 |
| IngestDate | Wed Aug 27 16:27:01 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c790-f51ebb214daa694d08b56faa9b05fedceb7357bec4fad740e91d51efc5b84f9b3 |
| ORCID | 0009-0004-1990-0196 0009-0002-4686-2119 0000-0001-8726-3062 0000-0003-0902-030X 0000-0003-0201-1021 0000-0002-1994-0591 |
| OpenAccessLink | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ange.202510400 |
| ParticipantIDs | crossref_primary_10_1002_ange_202510400 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-08-21 |
| PublicationDateYYYYMMDD | 2025-08-21 |
| PublicationDate_xml | – month: 08 year: 2025 text: 2025-08-21 day: 21 |
| PublicationDecade | 2020 |
| PublicationTitle | Angewandte Chemie |
| PublicationYear | 2025 |
| References | e_1_2_7_5_1 e_1_2_7_3_1 e_1_2_7_9_1 e_1_2_7_7_1 e_1_2_7_19_1 e_1_2_7_17_1 e_1_2_7_15_1 e_1_2_7_41_1 e_1_2_7_1_1 e_1_2_7_13_1 e_1_2_7_43_1 e_1_2_7_11_1 e_1_2_7_45_1 e_1_2_7_47_1 e_1_2_7_26_1 e_1_2_7_49_1 e_1_2_7_28_1 Berodier E. (e_1_2_7_31_1) 2016 e_1_2_7_50_1 e_1_2_7_25_1 e_1_2_7_52_1 e_1_2_7_23_1 e_1_2_7_33_1 e_1_2_7_54_1 e_1_2_7_21_1 e_1_2_7_35_1 e_1_2_7_56_1 e_1_2_7_37_1 e_1_2_7_39_1 e_1_2_7_6_1 e_1_2_7_4_1 e_1_2_7_8_1 e_1_2_7_18_1 e_1_2_7_16_1 e_1_2_7_40_1 e_1_2_7_2_1 e_1_2_7_14_1 e_1_2_7_42_1 e_1_2_7_12_1 e_1_2_7_44_1 e_1_2_7_10_1 e_1_2_7_46_1 e_1_2_7_48_1 e_1_2_7_27_1 e_1_2_7_29_1 e_1_2_7_51_1 e_1_2_7_30_1 e_1_2_7_53_1 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_55_1 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_20_1 e_1_2_7_36_1 e_1_2_7_38_1 |
| References_xml | – ident: e_1_2_7_13_1 doi: 10.3390/ma13081869 – ident: e_1_2_7_18_1 doi: 10.1039/D4DD00334A – ident: e_1_2_7_20_1 doi: 10.1039/D1SC04588A – ident: e_1_2_7_5_1 doi: 10.1038/s41467-024-47070-5 – ident: e_1_2_7_14_1 doi: 10.1021/acscatal.2c02743 – ident: e_1_2_7_12_1 doi: 10.1002/anie.200390303 – ident: e_1_2_7_10_1 doi: 10.1021/acs.oprd.3c00091 – ident: e_1_2_7_51_1 doi: 10.1126/science.1230444 – ident: e_1_2_7_24_1 doi: 10.1002/anie.202104318 – ident: e_1_2_7_45_1 doi: 10.1016/j.acthis.2024.152154 – ident: e_1_2_7_35_1 doi: 10.1016/j.egypro.2011.01.161 – ident: e_1_2_7_46_1 doi: 10.1039/D0TA00219D – ident: e_1_2_7_53_1 doi: 10.1021/ja500330a – ident: e_1_2_7_11_1 doi: 10.1039/D3SC06206F – ident: e_1_2_7_16_1 doi: 10.1177/24726303211047839 – ident: e_1_2_7_40_1 doi: 10.1016/j.micromeso.2017.06.001 – ident: e_1_2_7_43_1 doi: 10.1016/0143-7208(95)00067-4 – ident: e_1_2_7_37_1 doi: 10.1021/la000578m – ident: e_1_2_7_34_1 doi: 10.1002/xrs.560 – ident: e_1_2_7_30_1 doi: 10.1021/acs.chemmater.7b00441 – ident: e_1_2_7_7_1 doi: 10.1038/s44160-024-00494-9 – ident: e_1_2_7_38_1 doi: 10.3390/molecules26175419 – ident: e_1_2_7_41_1 doi: 10.3390/molecules28196951 – ident: e_1_2_7_54_1 doi: 10.1039/c3ta12497e – volume-title: A Practical Guide to Microstructural Analysis of Cementitious Materials year: 2016 ident: e_1_2_7_31_1 – ident: e_1_2_7_28_1 doi: 10.1039/C2CS35378D – ident: e_1_2_7_33_1 doi: 10.1615/JPorMedia.v16.i7.30 – ident: e_1_2_7_55_1 doi: 10.1126/science.aaa8075 – ident: e_1_2_7_3_1 doi: 10.1002/anie.202412045 – ident: e_1_2_7_49_1 doi: 10.1038/s41467-020-18639-7 – ident: e_1_2_7_4_1 doi: 10.1126/science.aav2211 – ident: e_1_2_7_6_1 doi: 10.1016/j.xcrp.2023.101633 – ident: e_1_2_7_17_1 doi: 10.1038/s41467-020-19926-z – ident: e_1_2_7_42_1 doi: 10.1007/s10895-024-04001-3 – ident: e_1_2_7_9_1 doi: 10.1126/science.ads0901 – ident: e_1_2_7_8_1 doi: 10.1002/anie.201600995 – ident: e_1_2_7_2_1 doi: 10.1039/D3SC06133G – ident: e_1_2_7_47_1 doi: 10.1021/acs.langmuir.3c00256 – ident: e_1_2_7_25_1 doi: 10.1038/s41563-021-01054-8 – ident: e_1_2_7_44_1 doi: 10.1016/j.crgsc.2021.100179 – ident: e_1_2_7_48_1 doi: 10.1002/adma.202201502 – ident: e_1_2_7_19_1 doi: 10.1002/anie.202413395 – ident: e_1_2_7_50_1 doi: 10.1002/anie.200701595 – ident: e_1_2_7_23_1 doi: 10.1002/adfm.201200591 – ident: e_1_2_7_1_1 doi: 10.1002/adma.202002780 – ident: e_1_2_7_56_1 doi: 10.1021/acs.accounts.1c00654 – ident: e_1_2_7_21_1 doi: 10.1016/j.chempr.2022.01.012 – ident: e_1_2_7_27_1 doi: 10.1039/C2CS35244C – ident: e_1_2_7_29_1 doi: 10.1021/ja3055639 – ident: e_1_2_7_15_1 doi: 10.1021/acscombsci.5b00049 – ident: e_1_2_7_22_1 doi: 10.1039/C2CS35251F – ident: e_1_2_7_52_1 doi: 10.3390/ma7043198 – ident: e_1_2_7_39_1 doi: 10.1021/jacsau.2c00389 – ident: e_1_2_7_32_1 doi: 10.1016/j.matpr.2023.03.716 – ident: e_1_2_7_26_1 doi: 10.1038/s41586-022-05310-y – ident: e_1_2_7_36_1 doi: 10.1021/jacs.5b00838 |
| SSID | ssj0006279 |
| Score | 2.3010073 |
| Snippet | Porous materials are important for many technologies, but the measurement of porosity by gas adsorption isotherms is slow, taking around one day per sample... |
| SourceID | crossref |
| SourceType | Index Database |
| Title | Accelerated Porosity Screening Using a Multichannel Colorimetric Array |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8QwEA4-DnoRn_gmB8HD0rVNk7Y5ri9UUERX0NOSpIkuSCvrLoK_3knTl4-DegklJGnJl05mJjNfENoTnHEdpJEnE8U8KsLQE76MPZkmjBgqfG5s7vDlVXR2Ry_u2X11wXiZXTKWXfX-Y17Jf1CFOsDVZsn-Adl6UKiAZ8AXSkAYyl9h3FMKdg1L9pB2rvNRXsRX3CobSmM9AC4cQHSKJFub4ZvpwlOQW0p_y8zf6Y1G4tO5bi971G_Chvh3CiqBBnbnKH2YvD5NahM-L_2h569i2PiVjydjp5IeDl9gjdWnHM_5m5NJN7lsOxsIs95Tl8FcCVBKvYQ4ltGuLmUmCUBOOZ7pbxLZMbzaRImuHTCwQqPZe6rz9i9bUh0o6EiVycD2H9T9p9EsAavAXlhxfNOwhUXEUStW31hxdPrk4PP7WzpIS5noL6KF0grAPQfpEprS2TKaO6ou31tBpy1ocQUtrqHFBbRY4Da0uA0tLqBdRf3Tk_7RmVdeeeGpmPueYYGWkgQ0FSLiNPUTySIjBJc-MzZeV8Yhi-G3o0akMfU1D1LoYhSTCTVchmtoJsszvY4wD6lvJDSRSlMNirwByySVmrJECZC8G2i_moPBiyM2Gfw825u_brmF5ptFs41mxqOJ3gGdbSx3C6Q-AMH0Qlo |
| linkProvider | Wiley-Blackwell |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Accelerated+Porosity+Screening+Using+a+Multichannel+Colorimetric+Array&rft.jtitle=Angewandte+Chemie&rft.au=Han%2C+Yushu&rft.au=Borne%2C+Isaiah&rft.au=Dutta%2C+Biplab&rft.au=Clowes%2C+Rob&rft.date=2025-08-21&rft.issn=0044-8249&rft.eissn=1521-3757&rft_id=info:doi/10.1002%2Fange.202510400&rft.externalDBID=n%2Fa&rft.externalDocID=10_1002_ange_202510400 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0044-8249&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0044-8249&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0044-8249&client=summon |