Abstract 1257: A MYC-Aurka protein complex represents an actionable target in p53 altered liver cancer

• Published in: Cancer research (Chicago, Ill.) Vol. 76; no. 14_Supplement; p. 1257
• Main Authors: Daniel, Dauch, Rudalska, Ramona, Cossa, Giacomo, Nault, Jean Charles, Imbeaud, Sandrine, Malek, Nisar P., Longerich, Thomas, Laufer, Stefan, Poso, Antti, Zucman-Rossi, Jessica, Eilers, Martin, Zender, Lars
• Format: Journal Article
• Language: English
• Published: 15.07.2016

Abstract Myc oncoproteins are causally involved in the genesis of a large fraction of human tumors. Three closely related Myc proteins, c-myc, N-myc and L-myc, have been implicated in cancer, whereas c-myc was identified as an important oncogenic driver in frequent solid tumors.Applying transposon-b...