C ontinuous multilayered composite hydrogel as osteochondral substitute

• Published in: Journal of biomedical materials research. Part A Vol. 103; no. 8; pp. 2521 - 2530
• Main Authors: Leone, G., Volpato, M. D., Nelli, N., Lamponi, S., Boanini, E., Bigi, A., Magnani, A.
• Format: Journal Article
• Language: English
• Published: 01.08.2015

Abstract Cartilage is a highly organized avascular soft tissue that assembles from nano‐to macro‐scale to produce a complex structural network. To mimic cartilage tissue, we developed a stable multilayered composite material, characterized by a tailored gradient of mechanical properties. The optimiz...