Fatal anaphylaxis in the United States, 1999-2010: Temporal patterns and demographic associations

• Published in: Journal of allergy and clinical immunology Vol. 134; no. 6; pp. 1318 - 1328.e7
• Main Authors: Jerschow, Elina, Lin, Robert Y., Scaperotti, Moira M., McGinn, Aileen P.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.2014; Elsevier; Elsevier Limited
• Subjects: Adult; African Americans; Age; Aged; Allergies; Allergy and Immunology; Anaphylaxis - etiology; Anaphylaxis - mortality; Asthma; Biological and medical sciences; Census of Population; Codes; Continental Population Groups; Contrast Media - adverse effects; death certificate; Demography; drug; Drug-Related Side Effects and Adverse Reactions - mortality; epidemiology; Fatal anaphylaxis; Female; Food; Food - adverse effects; Food Hypersensitivity - mortality; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Hispanic people; Humans; Immunopathology; Insect bites; Male; Medical sciences; Middle Aged; Mortality; Race; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Serum; United States - epidemiology; Venom; Venoms - adverse effects; Vital statistics; Young Adult; United States; North America; America; United Kingdom > UK; Australia; United States > US; epidemiology; venom; death certificate; ICD-10; Fatal anaphylaxis; food; drug; International Classification of Diseases, 10th revision; Drug; Allergy; Immunopathology; Anaphylaxis; Association; Immunology; Venom; Death certificate; Epidemiology; Food

Anaphylaxis-related deaths in the United States have not been well characterized in recent years. We sought to define epidemiologic features and time trends of fatal anaphylaxis in the United States from 1999 to 2010. Anaphylaxis-related deaths were identified by using the 10th clinical modification...