Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice - Cao, Simon; Jurczak, Michael J.; Shuda, Yoko; Sun, Rui; Shuda, Masahiro; Chang, Yuan; Moore, Patrick S. (PLOS ONE, 2023)
Keywords: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Signal Transducing - genetics; Alanine; Amino acid substitution; Amino acids; Animals; Biology and Life Sciences; Bone marrow; CDC2 Protein Kinase; CDC2 Protein Kinase - metabolism; Cell Cycle Proteins; Cell Cycle Proteins - metabolism; Cycles; Cyclin B1; Cyclin-dependent kinases; Development and progression; Diabetes; Diabetes mellitus; Diet; Engineering and Technology; Glucose; Glucose Intolerance; Glucose metabolism; Glucose tolerance; Glycerol; Health aspects; High fat diet; Homeostasis; Humans; Immunological tolerance; Initiation factor eIF-4E; Insulin resistance; Intolerance; Kinases; Male; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 1 - metabolism; Medicine; Medicine and Health Sciences; Metabolism; Methods; Mice; Mitosis; Muscles; Mutation; Mutation (Biology); Phosphoproteins; Phosphoproteins - metabolism; Phosphorylation; Physical Sciences; Protein arrays; Protein kinases; Proteins; Q; R; Research Article; Science; Stem cell transplantation; Substitutes; Substrates; Synapsins; Synapsins - metabolism; Tissues; TOR protein; Transit; Transplantation; Transplants; Transplants & implants; United States