Low frequency of asymptomatic dengue virus-infected donors in blood donor centers during the largest dengue outbreak in Taiwan

• Published in: PLOS ONE Vol. 13; no. 10; p. e0205248
• Main Authors: Tsai, Jih-Jin, Lin, Ping-Chang, Tsai, Ching-Yi, Wang, Ying-Hui, Liu, Li-Teh
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science (PLoS) 08.10.2018; Public Library of Science
• Subjects: Accreditation; Adult; Antibodies, Viral; Antibodies, Viral - blood; Antibodies, Viral - isolation & purification; Antigens; Asymptomatic Infections; Asymptomatic Infections - epidemiology; Biology and life sciences; Blood; Blood & organ donations; Blood Donors; Blood Transfusion; Blood transfusions; Care and treatment; Dengue; Dengue - blood; Dengue - epidemiology; Dengue - immunology; Dengue - transmission; Dengue fever; Dengue Virus; Dengue Virus - immunology; Dengue Virus - isolation & purification; Diagnosis; Disease control; Disease Outbreaks; Disease Outbreaks - prevention & control; Disease transmission; Enzyme-linked immunosorbent assay; Epidemics; Female; Fever; Genomes; Health aspects; Hospitals; Humans; Immunoglobulin G; Immunoglobulin M; Infections; Infectious diseases; Male; Medical laboratories; Medical technology; Medicine; Medicine and Health Sciences; Middle Aged; Mosquitoes; Outbreaks; People and Places; Plaque assay; Polymerase chain reaction; Prevalence; Q; R; Real time; Real-Time Polymerase Chain Reaction; Research and Analysis Methods; Research Article; Reverse transcription; Ribonucleic acid; Risk factors; RNA; RNA, Viral; RNA, Viral - isolation & purification; Science; Serogroup; Serologic Tests; Serologic Tests - methods; Taiwan; Taiwan - epidemiology; Tissue donors; Transfusion; Vector-borne diseases; Viral diseases; Viral Nonstructural Proteins; Viral Nonstructural Proteins - immunology; Viral Nonstructural Proteins - isolation & purification; Viruses; Young Adult; Taiwan; Saudi Arabia; Australia; China

To determine the prevalence of asymptomatic dengue virus-infected blood donors during the largest dengue outbreak in Taiwan history occurred in 2015, we examined the evidence of dengue virus (DENV) infection by the detection of DENV RNA genome using real-time reverse transcription-polymerase chain r...